Deuterated Compounds

Applications Ethylene Glycol Dicaprate-d4 is a deuterated version of Ethylene Glycol Dicaprate (E917474), a plasticizer for chloroethylene polymers. References Van V. G. J., et al.: Kunststoffe, 57, 561 (1967); Van V. G. J., et al.: Plastica, 19, 175 (1966)

Sodium acetate-13C2 is a plant metabolite that is produced by the metabolism of acetate. It has been postulated to be involved in plant defense against pathogens and pests. The 13C label was used to track the metabolite through various metabolic pathways, including phytoalexins, detoxification, and degradation. The unlabelled form of the molecule was used for chromatographic techniques to detect its presence in plants. The high values obtained from these methods were quantified and compared with known concentrations of phytuberin, a phytoalexin found in tobacco plants. The results suggest that this metabolite may play a role in plant pathogen resistance.

Applications Glycine-13C2,15N p-Toluenesulfonate is a by-product of an intermediate during the synthesis of m-Hydroxyhippuric Acid-13C2, 15N (H943127), a labelled m-Hydroxyhippuric Acid (H943125) which is a metabolite of caffeic and chlorogenic acids in human. References Booth, A., et al.: J. Biol. Chem., 229, 51 (1957); Gonthier, M., et al.: Biomed. Pharmacother., 60, 536 (2006)

Applications N-Fmoc-(13C9,15N)-L-Tyrosine O-Tertbutyl Ether is the isotope labelled protected form of L-Tyrosine (T899975), an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones. References Gülçin, ?.: Amino Acids, 32, 431 (2007); Langen, K., et al.: Nuc. Med. Biol., 29, 625 (2002); Schallreuter, K., et al.: J. Invest. Derm., 104, 953 (1995); Zhang, W., et al.: Neuropharmacology, 47, 438 (2004)

Applications Benzyl-alpha,alpha-d2 Alcohol (CAS# 21175-64-4) is a useful isotopically labeled research compound.

Applications N,N-Dimethyldodecylamine-d6 is the isotope labelled analog of N,N-Dimethyldodecylamine. N,N-Dimethyldodecylamine is used as a reagent in the synthesis of epoxy quaternary ammonium salt surfactants which exhibit potential antibacterial activity. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Liu, Y., et al.: J. Disper. Sci. Technol., 35, 1460 (2014)

Applications Diethyl-2,2,2,2',2',2'-d6-amine HCl (CAS# 1219805-68-1) is a useful isotopically labeled research compound.

Applications Labelled N-Nitrosopiperidine (N545370). A carcinogenic nitrosocompound. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bos, J., et al.: Cancer Res., 49, 4682 (1989), Wong, H., et al.: Carcinogenesis, 24, 291 (2003), Gonzalez-Mancebo, S., et al.: Mutat. Res., 558, 45 (2004), Gonzalez, M., et al.: Bioorg. Med. Chem., 13, 601 (2005),

Applications 2,3,5-Trimethylphenol-d11 (CAS# 362049-46-5) is a useful isotopically labeled research compound.

Applications Labelled Maleic Anhydride. A heterocyclic compound used in the manufacture of unsaturated polyester resins. Maleic Anhydride has a wide range of other applications; it is used in synthetic tensides, insecticides, herbicides and fungicides. References Hanafi, W.Z.A. et al.: Plast. Rub. Comp. Proc. Appl., 19, 175 (1993); Noma, K. et al.: Shik. Kyok., 36, 225 (1963); Augustin, M. et al.: Wissen. Zeitsch., 25, 5 (1976); Jiang, Q. et al.: Nongyao, 49, 257 (2010);

Applications Labelled 2-Aminothiazoline-4-carboxylic acid (A630330). Used in the manufacturing of L-tryptophan by enzymic reaction. References Franke, L., et al.: J. Med. Chem., 48, 6997 (2005), Fox, T., et al.: Curr. Top Med. Chem., 6, 1579 (2006),