Antibiotics

A broad-spectrum antibiotic of macrolide class, which targets 50S ribosomal subunit and inhibits protein synthesis. Erythromycin is widely used in molecular biology and biotechnology as a selection marker. Erythromycin is also an agonist of the motilin receptor, and it has prokinetic activity on the gut.

Stability Hygroscopic Applications Piperacilloic Acid-Piperacillin Dimer Disodium Salt is Piperacillin (P479950) impurity and can be obtained from it. Piperacillin (P479950) is broad spectrum semi-synthetic antibiotic related to Penicillin. Antibacterial. References Takai, A., et al.: Chemotherapy, 25, 816 (1977); Bodey, G.P., et al.: Antimicrob. Agents Chemother., 14, 78 (1978); Kuck, N.A., et al.: J. Antibiot., 31, 1175 (1978);

Cefpiramide acid (Cefpiramidum) is a third-generation cephalosporin antibiotic.

Tunicamycin, inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells. Also available as a 25 mM solution in DMSO. Antibacterial and antifungal. Blocks the formation of protein N-glycosidic linkages This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Vulgamycin is a novel antibiotic, which is derived from a specific strain of soil bacteria belonging to the genus *Streptomyces*. This microorganism is known for its prolific secondary metabolite production, enabling the development of unique compounds with therapeutic potential. Vulgamycin operates by inhibiting bacterial cell wall synthesis, a mechanism of action that targets key enzymatic pathways, resulting in effective bactericidal activity against a wide range of Gram-positive bacteria. The compound's applications are primarily in the treatment of resistant bacterial infections. Due to its unique mode of action, Vulgamycin is effective in combating strains that have developed resistance to traditional antibiotics. Its use is particularly significant in clinical settings where antibiotic resistance poses a substantial challenge, particularly with pathogens like *Staphylococcus aureus* and *Enterococcus* species. Ongoing research is focused on understanding its full spectrum of activity, optimizing its pharmacokinetics, and evaluating its use in combination therapy to broaden its therapeutic potential.