Antifungals

Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against

1-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7-quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is a fluoroquinolone antibiotic, engineered through synthetic chemistry. It is derived from chemical sources involving complex organic synthesis, highlighting its intricate molecular architecture. Its mode of action is distinctive, as it inhibits bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. This interference with bacterial DNA processes results in bactericidal effects, effectively eliminating susceptible bacterial strains. This compound serves primarily in the treatment of various bacterial infections, demonstrating utility against a range of gram-positive and gram-negative bacteria. Its application extends to clinical settings where resistant bacterial strains pose significant challenges, making it a critical tool in antimicrobial therapy. The structural sophistication of this compound allows it to maintain efficacy where other antibiotics may fail, due to its enhanced binding affinity and resistance to common resistance mechanisms.

Thifluzamide is a fungicide widely used to control crop diseases.

Anti-fungal; glucan synthase inhibitor

Myclobutanil (Systhane) is a triazole chemical used as a fungicide.

Fenticonazole nitrate is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal infections like vaginal thrush and athlete's foot.

Triticonazole is a triazole pesticide and fungicide. Triticonazole shows endocrine disrupting activities.

Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.

Activator of the two-pore domain potassium channel TASK3

Prodigiosin is a secondary metabolite of Symbiotic bacteria. It also has anti-fungal and anti-cancer activity.

Chlormidazole hydrochloride (Clomidazole hydrochloride) has inhibitory activity against many fungi and some gram-positive cocci.

Atovaquone is an antimicrobial drug that is used for the treatment of Pneumocystis jirovecii pneumonia. This drug is an analog of ubiquinone and has good in vitro activity against Toxoplasma gondii. Atovaquone is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Xanthoxylin (Brevifolin) is a borneol and camphor tasting compound and can be found in a number of food items such as fats and oils, herbs and spices,