Antifungals

MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal anti-inflammatory activity that acts through interaction with Glu396 study ulcerative colitis.

Camalexin: a phytoalexin from Camelina sativa with antifungal, antibacterial, anticancer properties and induces ROS.

Polygodial (Tadeonal) is an antifungal potentiator and an antibiotic, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana.

Fosetyl-aluminum is a systemic fungicide that controls downy mildews and Phytophthora diseases, used on a variety of crops including fruits and vegetables。

Inhibitor of glucan synthase; antifungal compound

Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain.

Triadimenol (UK 199) is a triazole fungicide that is cardiotoxic and promotes reactive oxygen species (ROS) production and apoptosis in zebrafish.

Miconazole is an antifungal drug that is used for the treatment of fungal infections. This drug has broad-spectrum activity and works by inhibiting fungal CYP450 14α-lanosterol demethylase activity. This leads to altered ergosterol production and an impaired cell membrane. Miconazole nitrate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Applications Methyl 2-Cyano-2-oximinoacetate is an intermediate in synthesizing 2-Cyano-2-(methoxyimino)acetic Acid (C989423), which is a cyano-oxime derivative used as a fungicide. References Tellier, F., et al.: Pestic Biochem Physiol., 78, 151-160 (2004)

4-Methylcinnamic acid is a cinnamic acid analog that can be used as an intervention catalyst to overcome antifungal tolerance.

Efinaconazole is a triazole antifungal agent with action on fungal 14α-demethylase to inhibit ergosterol synthesis and is used for treating onychomycosis (fungal nail infections).

Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections.

Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.

Curcumol ((-)-Curcumol), a pure monomer isolated extracted from Rhizoma Curcumaeis, has antitumor activities.

Latrunculin B: alkaloid, inhibits actin polymerization, antifungal, antiprotozoal, modulates heart rhythm, studied in glaucoma.

Propiconazole is a triazole fungicide with action on fungal cell membranes by inhibiting ergosterol biosynthesis and is used for controlling fungal diseases in crops and turf.

Dihydropenicillin F potassium is a novel antibiotic compound, which is semisynthetic in nature, derived from the penicillin family. It is sourced through the modification of natural penicillins, bringing about enhanced stability and efficacy against certain resistant bacterial strains. The mode of action involves the inhibition of bacterial cell wall synthesis, primarily targeting the penicillin-binding proteins (PBPs). This disruption consequently leads to cell lysis and the eventual bacterial death. The applications of Dihydropenicillin F potassium are primarily in the clinical management of bacterial infections that have developed resistance to earlier forms of penicillin. Its enhanced efficacy makes it particularly valuable in treating infections caused by Gram-positive bacteria. The incorporation of potassium aids in the solubility and bioavailability of the compound, facilitating its use in intravenous preparations. Ongoing research is exploring its potential synergy with other antimicrobial agents to broaden its effectiveness and counteract multidrug-resistant pathogens.