Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Products of "Antiparasitics"
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DHFR-IN-20
DHFR-IN-20 (Compound LA1) is an inhibitor of dihydrofolate reductase (DHFR) targeting the malignant strains of the malaria parasite. It exhibits inhibition constants (Kis) of 0.16 nM, 0.30 nM, and 6.6 nM for PfDHFR-WT, PfDHFR-QM, and HsDHFR, respectively. Additionally, DHFR-IN-20 demonstrates antimalarial activity, with IC50 values of 1.4 nM against parasites carrying the wild-type (TM4/8.2) PfDHFR enzyme and 1.6 μM against those with the quadruple mutation (V1/S)PfDHFR.Color and Shape:Odour SolidBenzeneacetonitrile, 2,6-dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-
CAS:Formula:C17H9Cl3N4O2Purity:98%Color and Shape:SolidMolecular weight:407.637967-Chloro-3-iodo Hydroxychloroquine
CAS:Controlled ProductFormula:C18H25ClIN3OColor and Shape:NeatMolecular weight:461.77DHFR-IN-3
CAS:DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.Formula:C8H7BrN4Purity:99.59% - 99.61%Color and Shape:SolidMolecular weight:239.07LN002
CAS:LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Formula:C22H15N7Color and Shape:SolidMolecular weight:377.40Antileishmanial agent-19
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L.Formula:C22H18N4O3Purity:98%Color and Shape:SolidMolecular weight:386.4DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Formula:C21H24Cl2N6O2SPurity:97.8% - 99.76%Color and Shape:SolidMolecular weight:495.43Ref: TM-T27135
1mg96.00€5mg279.00€10mg420.00€25mg682.00€50mg947.00€100mg1,301.00€200mg1,738.00€1mL*10mM (DMSO)305.00€Primaquine diphosphate
CAS:Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties.Formula:C15H21N3O·2H3PO4Purity:98.06% - 99.73%Color and Shape:Orange PowderMolecular weight:455.34Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Formula:C17H16F6N2OPurity:99.97%Color and Shape:SolidMolecular weight:378.31Ref: TM-T0860L
1mg70.00€5mg154.00€10mg225.00€25mg376.00€50mg538.00€100mg755.00€200mg1,017.00€1mL*10mM (DMSO)160.00€3-Chloro-N-(3-methoxyphenyl)propanamide
CAS:Controlled ProductApplications 3-Chloro-N-(3-methoxyphenyl)propanamide acts as an inhibitor towards DOXP-reductoisomerase (DXR), a primary target for antimalarial drugs. References Bodill, T. et al.: Bioorg. Med. Chem., 21, 4332 (2013);Formula:C10H12ClNO2Color and Shape:NeatMolecular weight:213.66Niclosamide
CAS:Formula:C13H8Cl2N2O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:327.12Rafoxanide, Vetranal
CAS:Formula:C19H11Cl2I2NO3Purity:99%Color and Shape:SolidMolecular weight:626.0105Metronidazole acetic acid
CAS:Metronidazole acetic acid, a mutagenic metabolite of an antibiotic, targets protozoa and anaerobic bacteria.Formula:C6H7N3O4Purity:98%Color and Shape:SolidMolecular weight:185.1375Didesethyl Chloroquine Hydroxyacetamide
CAS:Controlled ProductApplications An intermediate in the preparation of Cletoquine Oxalate It is a COVID19-related research product.Formula:C16H20ClN3O2Color and Shape:NeatMolecular weight:321.80SDZ285428
CAS:SDZ285428 is a CYP24A1 inhibitor.Formula:C24H20ClN3OPurity:97.51%Color and Shape:SolidMolecular weight:401.89Ref: TM-T4188
2mg37.00€5mg52.00€10mg90.00€25mg170.00€50mg255.00€100mg375.00€200mg533.00€1mL*10mM (DMSO)58.00€1-Piperazinecarboxamide, N,N-diethyl-4-methyl-
CAS:Formula:C10H21N3OPurity:97%Color and Shape:SolidMolecular weight:199.29324000000003Rafoxanide
CAS:Anthelmintic; anti-parasiticFormula:C19H11Cl2I2NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:626.01 g/molMorantel tartrate
CAS:Morantel tartrate (CP-12009-18 tartrate) is an antinematodal agent used mainly for livestock.Formula:C16H22N2O6SPurity:99.86%Color and Shape:White Or Pale Yellow Crystalline PowderMolecular weight:370.42Modoflaner
CAS:Modoflaner is an antiparasitic (veterinary use).Formula:C23H10F12IN3O2Purity:98.4%Color and Shape:SolidMolecular weight:715.23
