Flavonoids

7-Hydroxy-2',5,8-trimethoxyflavanone is a flavonoid compound, which is a type of naturally occurring phenolic compound. It can be sourced primarily from certain plant species, where it plays a role in the plant's defense mechanism against environmental stressors. Flavonoids like this one often exhibit a variety of biological activities. The mode of action of 7-Hydroxy-2',5,8-trimethoxyflavanone involves the modulation of several cellular pathways, including those related to oxidative stress and inflammation. Its structure allows it to act as an antioxidant, scavenging free radicals and contributing to minimizing oxidative damage to cells. Additionally, it may interact with specific enzymes and receptors, influencing metabolic and signaling pathways. In scientific research, this compound is being explored for its potential therapeutic applications, which include anti-inflammatory, anticancer, and neuroprotective effects. Its antioxidant properties make it a subject of interest in studies focused on diseases where oxidative stress is a contributing factor. Further research is required to fully elucidate its biological effects and potential in clinical applications.

Sciadopitysin shows protective effects on antimycin A-induced toxicity in osteoblastic MC3T3-E1 cells, it may reduce or prevent osteoblasts degeneration; it also may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis. Sciadopitysin can inhibit the Aβ aggregation and reduce Aβ-induced toxicity in the primary cortical neurons.

Oxygen-heterocyclic compound

3',4',5'-Trimethoxyflavanone is a specialized flavonoid compound, which is synthesized from natural sources, such as plants belonging to the flavonoid family. This compound is characterized by its distinctive methoxy group modifications on the flavanone backbone, enhancing its bioactive potential. Its mode of action involves modulation of various biochemical pathways, including antioxidant systems and inflammatory mediators. By stabilizing free radicals and inhibiting pro-inflammatory enzymes, 3',4',5'-Trimethoxyflavanone plays a crucial role in cellular protection and homeostasis. In research settings, this compound is primarily utilized for its potential therapeutic effects, particularly in the study of oxidative stress and inflammation-related conditions. Its applications extend to investigations in pharmacology and biochemistry, where it serves as a model compound to understand the mechanistic pathways of flavonoids. Additionally, its effects on cellular signaling pathways make it a valuable tool for exploring novel drug targets. With ongoing studies, 3',4',5'-Trimethoxyflavanone continues to contribute to our understanding of flavonoid chemistry and its implications in health and disease.

4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Natural glycoside

3,5-Dihydroxyflavone is a flavonoid compound, which is a type of natural product commonly found in plants. This compound is derived from various plant sources, where it serves as a secondary metabolite involved in plant defense mechanisms. 3,5-Dihydroxyflavone exerts its effects through several mechanisms, including modulating oxidative stress and interacting with cellular signaling pathways. Its antioxidant properties allow it to scavenge free radicals, thereby protecting cells from oxidative damage. Additionally, it can influence various enzymes and receptors involved in cellular processes, leading to a range of biological effects. The applications of 3,5-Dihydroxyflavone are diverse, as it has been studied for its potential role in therapeutic settings. Research has explored its use in neuroprotection, given its ability to influence pathways involved in neuronal survival and plasticity. Moreover, its anti-inflammatory properties make it a compound of interest in conditions characterized by chronic inflammation. Ongoing studies continue to investigate its multifaceted roles, aiming to further elucidate its mechanisms and potential applications in health and disease contexts.

Natural glycoside

Oxygen-heterocyclic compound

3,7,8,4'-Tetrahydroxyflavone is a naturally occurring flavonoid, which is a type of secondary metabolite commonly found in various plants. It is derived from botanical sources like fruits, vegetables, and certain herbs. This compound has gained attention due to its potential biological activities linked to its structural properties, specifically the presence of multiple hydroxyl groups that contribute to its antioxidant capacity. The mode of action of 3,7,8,4'-Tetrahydroxyflavone involves scavenging reactive oxygen species (ROS), thereby reducing oxidative stress within biological systems. This antioxidative mechanism can protect cells from damage caused by free radicals, suggesting a potential role in counteracting certain degenerative diseases. The uses and applications of 3,7,8,4'-Tetrahydroxyflavone are primarily centered on research into its therapeutic potential. Studies are being conducted to understand its effectiveness in modulating pathways involved in inflammation, cancer, and cardiovascular diseases. This compound continues to be of significant interest for scientists exploring novel phytochemicals with beneficial health effects and therapeutic potential.

Irisflorentin prevents cell death, boosts proteasomes via rpn-3, reduces egl-1, and lowers iNOS/NO in LPS-stimulated macrophages.