Flavonoids

3',4',5',5,7-Pentamethoxyflavone, a Rutaceae brassinosteroid, thwarts cancer by blocking Nrf2, aiding chemotherapy.

Oxygen-heterocyclic compound

Oxygen-heterocyclic compound

Gossypin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Apigenin - 94% is a purified form of apigenin, which is a naturally occurring flavonoid. It is primarily sourced from various plant species, including parsley, celery, and chamomile, where it is a prominent active component. The mode of action of apigenin involves multiple biochemical pathways: it acts as an anti-inflammatory agent, modulates enzyme activities, and exhibits antioxidant properties by scavenging free radicals. Additionally, apigenin interacts with cellular signaling pathways, such as the MAPK and PI3K/Akt, which contribute to its protective effects against oxidative stress and its potential in promoting apoptosis in cancerous cells. Apigenin - 94% is widely used in scientific research due to its diverse biological activities. It is under investigation for its potential therapeutic applications, including anti-cancer, anti-inflammatory, and neuroprotective effects. Researchers are also exploring its role in cardiovascular health and its ability to modulate anxiety and depression. This compound serves as an important tool in pharmacological studies aimed at understanding the molecular mechanisms underpinning these health benefits, and it is considered a promising candidate for the development of novel therapeutic agents.

Please enquire for more information about 5-Hydroxy-3',4'-dimethoxyflavone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Procyanidin C1 analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Natural glycoside

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Formononetin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

5,3',4'-Trihydroxyflavone is a natural flavonoid compound often found in a variety of plants. This compound is derived from numerous botanical sources, including fruits and vegetables known to contain flavonoids, which are secondary metabolites widely distributed in the plant kingdom. The mode of action of 5,3',4'-Trihydroxyflavone involves its ability to interact with diverse biological pathways, often exhibiting antioxidant, anti-inflammatory, and potential anti-cancer effects. This interaction occurs through the modulation of enzyme activity and signaling pathways, as well as the scavenging of free radicals, thereby protecting cells from oxidative stress and damage. In scientific applications, 5,3',4'-Trihydroxyflavone is studied for its promising therapeutic potential. Research efforts focus on its role in preventing or treating chronic diseases associated with oxidative stress, such as cardiovascular diseases, neurodegenerative disorders, and specific types of cancer. Additionally, its bioavailability and metabolism are of keen interest, as they determine the efficacy and therapeutic outcomes in potential medical applications. The use of 5,3',4'-Trihydroxyflavone in scientific research highlights its multifaceted role in health and disease, offering potential insights into novel therapeutic strategies.

(+)-Afzelechin (Afzelechin) can be isolated from Eysenhardtia subcoriacea and is an α-glucosidase inhibitor.

Applications 8,9-Di-O-methyl-urolithin D is a derivative of Urolithin D (U847020) which is used in biological studies to evaluate DNA gyrase inhibitory activity of ellagic acid derivatives. References Weidner-Weels, M. A., et al: Bioorg. Med. Chem. Lett., 8, 97 (1998)

Beta-Naphthoflavone is a synthetic polycyclic aromatic compound, which is a laboratory-created substance designed to mimic naturally occurring compounds. It is a model compound widely used in scientific research due to its ability to induce specific enzyme pathways. Beta-Naphthoflavone primarily affects the aryl hydrocarbon receptor (AhR) pathway. Upon binding to this receptor, it modulates the expression of genes involved in xenobiotic metabolism, particularly influencing the cytochrome P450 enzymes. These enzymes play a crucial role in the metabolism of various xenobiotics and endogenous compounds. The applications of beta-Naphthoflavone are extensive in the field of biochemical and toxicological research. It is often utilized in vitro to study the mechanisms of enzyme induction and to explore the effects of environmental toxins. Additionally, researchers use it as a tool to understand the molecular pathways associated with the detoxification processes in cells. Its role in altering gene expression also makes it valuable for studying carcinogenesis and assessing the regulatory mechanisms of gene-environment interactions.

3'-Hydroxy-3,5,7,8,4'-pentamethoxyflavone is a specialized flavonoid compound, which is typically derived from various plant sources. This compound is part of the flavone subclass of flavonoids, known for their wide presence in the plant kingdom, contributing to the plant's pigmentation and offering various physiological benefits. The mode of action for 3'-Hydroxy-3,5,7,8,4'-pentamethoxyflavone primarily involves antioxidant activity, where it functions to neutralize free radicals and reduce oxidative stress within biological systems. This property is crucial in mitigating cellular damage, thus playing a role in the prevention of various degenerative diseases. Due to its potent antioxidant activity, the uses and applications of 3'-Hydroxy-3,5,7,8,4'-pentamethoxyflavone are of significant interest in biomedical research. It is explored for its potential therapeutic applications in combating oxidative stress-related conditions and contributing to the understanding of natural antioxidant mechanisms. Researchers in phytochemistry and pharmacology are particularly interested in this compound for its prospective role in developing nutraceuticals and other health-promoting formulations.