Flavonoids

Natural glycoside

Hesperidin is a bioflavonoid compound, which is derived from citrus fruits such as oranges and lemons. It acts primarily as an antioxidant and anti-inflammatory agent. Hesperidin functions by scavenging free radicals and enhancing the activity of antioxidant enzymes, thereby reducing oxidative stress within cells. Additionally, it modulates various signaling pathways involved in inflammation, leading to decreased expression of pro-inflammatory cytokines. Hesperidin is utilized in a variety of scientific and medical applications. It is often studied for its potential role in cardiovascular health, where it may improve vascular function and reduce blood pressure. Its anti-inflammatory properties make it a candidate for conditions characterized by chronic inflammation, such as arthritis. Moreover, hesperidin's impact on the immune system has been explored in contexts ranging from allergy management to viral infections. Researchers are also investigating its potential neuroprotective effects, which could have implications for neurodegenerative diseases. As such, hesperidin presents a promising avenue for future therapeutic development across multiple domains of health and disease.

Kwakhurin is a natural compound, characterized as an isoflavone, which is derived from the plant Pueraria mirifica. This plant is traditionally found in Southeast Asia and has been used in traditional medicine for various health benefits. Kwakhurin acts primarily as a phytoestrogen, meaning it can mimic the activity of estrogen in the body by binding to estrogen receptors. This behavior enables it to potentially modulate hormonal balances and exert estrogenic effects. The applications of Kwakhurin are diverse, particularly in the field of medical research. It is investigated for its potential benefits in managing menopausal symptoms, supporting bone health, and serving as an antioxidant. Current studies are also exploring its role in cardiovascular health and its efficacy in other hormone-related conditions. Its bioactivity may offer insights into developing therapeutic agents targeted at estrogen-related disorders.

5,7,2',4'-Tetrahydroxy-8,3'-di(gamma,gamma-dimethylallyl)-isoflavanone is a prenylated isoflavanone, which is a type of flavonoid compound extensively studied in natural product chemistry. It is primarily sourced from specific plant species known for their rich secondary metabolite profiles, often within the Fabaceae family. The mode of action of this compound involves its interaction at the molecular level with various biological targets, potentially leading to antioxidant, anti-inflammatory, or antimicrobial effects. These actions are mediated through the compound’s ability to modulate enzyme activities, interact with cellular membranes, and influence signaling pathways. Researchers are particularly interested in its applications within pharmacological studies, where it is explored for its therapeutic potential in disease prevention and treatment. In addition to its direct bioactivities, it may serve as a lead compound in drug discovery due to its unique structural attributes that can be optimized for improved efficacy and safety. This compound exemplifies the continuing interest in plant-derived compounds for medical and biotechnological advancements.

6-Prenylpinocembrin is a prenylated flavonoid compound, which is derived from various natural sources, particularly plants such as those found in the Leguminosae family. This compound is characterized by the addition of a prenyl group to the flavonoid pinocembrin, enhancing its lipophilicity and potential biological activity. The compound's mode of action is largely attributed to its ability to modulate various cellular pathways, including antioxidant, anti-inflammatory, and antimicrobial activities. It interacts with cellular signaling pathways to exert its effects, potentially impacting processes such as apoptosis, cell proliferation, and oxidative stress responses. The prenyl group is believed to facilitate cell membrane interaction, which may contribute to its enhanced bioactivity compared to non-prenylated flavonoids. 6-Prenylpinocembrin has garnered attention in scientific research due to its promising pharmacological properties. It is being investigated for various applications, including its potential as an anti-cancer agent, a neuroprotective compound, and its role in preventing or treating metabolic disorders. Continued research is warranted to fully elucidate its mechanism of action and therapeutic potential in these areas.

Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase.

Tamarixetin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Neobavaisoflavone, exhibits inhibitory activity against DNA polymerase and platelet aggregation, it also has striking anti-inflammatory and anti-cancer effects, Neobavaisoflavone can significantly inhibit the production of reactive oxygen species (ROS), reactive nitrogen species (RNS) and cytokines: IL-1β, IL-6, IL-12p40, IL-12p70, TNF-α in LPS+IFN-γ- or PMA- stimulated RAW264.7 macrophages.

Ketone with other oxygen functions

Chrysoeriol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Induces cell death in human prostate cancer by disrupting mitochondria function