Flavonoids

2'-Hydroxyflavonol is a flavonoid derivative, which is a polyphenolic compound commonly found in plants. This compound is derived from natural sources, particularly various fruits, vegetables, and roots. Its mode of action is primarily through its role as an antioxidant, where it scavenges free radicals, thereby reducing oxidative stress. Furthermore, it can modulate multiple signaling pathways, contributing to its various bioactivities. 2'-Hydroxyflavonol has been studied extensively for its potential applications in the fields of pharmacology and biochemistry. It has exhibited properties such as anti-inflammatory, antimicrobial, and anticancer activities in different experimental models. Researchers are interested in its potential as a therapeutic agent due to its ability to interact with and modulate biological processes. Additionally, it serves as a valuable compound in the study of flavonoid activity and their mechanisms of action in living systems, offering insights into its possible roles in disease prevention and health promotion.

Prunetin-4'-glucoside is a specialized flavonoid compound, categorized as a glucoside, which is derived from natural plant sources. This glycosylated form of prunetin is found in various plants and serves as part of the plant's defense mechanism. Its mode of action involves antioxidative properties that neutralize free radicals, thus protecting cellular structures from oxidative damage. This mechanism is crucial as oxidative stress is implicated in numerous diseases. Scientific studies are exploring the potential applications of Prunetin-4'-glucoside in the field of medicine and nutrition due to its antioxidative capabilities. It is being investigated for its role in modulating inflammatory pathways and its potential therapeutic effects in cardiovascular diseases, metabolic disorders, and neurodegenerative conditions. Additionally, the compound's ability to act as a signaling molecule makes it an interesting candidate for further biochemical and pharmacological studies. As our understanding deepens, Prunetin-4'-glucoside may become a significant component in the development of novel therapeutic agents.

Isorhamnetin-3-O-galactoside analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Eriodictyol-7-O-glucoside, a flavonoid in pistachio skin, activates Nrf2 and protects against Cisplatin toxicity.

5,6,7-Trimethoxyflavone is a specialized flavonoid compound, which is derived from natural plant sources. This compound exists primarily in certain species of the plant kingdom, such as citrus fruits, where it is part of a group of polyphenolic compounds known for their diverse biological activities. Its structure is characterized by the presence of three methoxy groups at positions 5, 6, and 7 on the flavone backbone, contributing to its distinct biochemical properties. The mode of action of 5,6,7-Trimethoxyflavone involves interaction with various cellular pathways, including enzyme modulation and receptor activity. It has been shown to influence pathways related to anti-inflammatory, antioxidant, and anti-cancer activities, although the precise mechanisms underpinning these actions are complex and multifaceted. Its ability to interfere with and modulate intricate signaling cascades makes it a compound of great interest in pharmacological research. The applications of 5,6,7-Trimethoxyflavone are broad, encompassing potential therapeutic uses in areas such as oncology, neurology, and cardiovascular health. Research and clinical studies are ongoing to explore its full spectrum of benefits and to better understand its physiological impacts and therapeutic potential.

Oxygen-heterocyclic compound

Quercetin 3-b-D-galactoside is a flavonoid glycoside, which is a type of polyphenolic compound. It is derived primarily from various fruits and vegetables, as it is a naturally occurring plant metabolite. This compound acts as an antioxidant, scavenging free radicals and reducing oxidative stress. Quercetin 3-b-D-galactoside is studied for its potential anti-inflammatory and antihypertensive effects. Its antioxidative properties make it a candidate for research into neuroprotective and cardioprotective applications. Additionally, it may play roles in modulating immune responses and protecting cells against various forms of damage. This compound is of interest in the field of natural product research and biochemistry for its potential therapeutic applications, as well as its role in plant biology. Scientists investigate it to understand better the mechanisms by which flavonoids can contribute to health and disease prevention. Its ability to interact with multiple cellular pathways positions it as a valuable compound for further exploration in medicinal chemistry and nutrition science.

Apigenin-7-glucoside is a naturally occurring flavonoid glycoside, which is derived primarily from various plant sources, including parsley, celery, chamomile, and some fruits. This compound is formed when apigenin, a flavonoid, is conjugated with a glucose molecule. The interaction with glucose enhances its solubility and bioavailability in biological systems. The mode of action of Apigenin-7-glucoside involves modulation of various biological pathways. It exhibits antioxidant properties by scavenging free radicals and inhibiting oxidative stress. Additionally, it may interact with cellular signaling pathways involved in inflammation and cell cycle regulation, potentially exerting anti-inflammatory and anti-cancer effects. Apigenin-7-glucoside is utilized in research for its potential therapeutic applications. It is studied for its role in preventing oxidative damage and managing inflammatory conditions. Its effects on cellular proliferation and apoptosis make it a candidate for cancer research. Understanding its bioactivity may contribute to the development of pharmaceuticals or nutraceuticals aimed at improving health outcomes related to oxidative stress and inflammation.

Natural glycoside

Flavanone hydrazone (FH) is a natural compound that has been found to have antiviral activity against a number of viruses, including the papilloma virus and picornavirus. The antiviral activity of FH is due to its ability to inhibit the shikimate pathway, which is required for the synthesis of aromatic amino acids from chorismate. This inhibition prevents the production of viral proteins, leading to cell death. FH also has an inhibitory effect on hepatitis C virus and leukoplakia by inhibiting fatty acid synthesis. It may also be used in the treatment of inflammatory diseases such as rheumatoid arthritis and ulcerative colitis.

Applications rac-Hesperetin 7-O-Sulfate Sodium Salt is a metabolite of rac-Hesperetin (H289501); a derivative of Hesperidine (H281185) with potential antihyperglycemic activity. References Zhang, B., et al.: Bioorg. Med. Chem. Lett., 22, 7194 (2012)

4',7-Dimethoxyisoflavone is a synthetic isoflavone, which is structurally related to compounds naturally found in certain plants, particularly legumes. This compound is engineered to mimic the bioactive properties of naturally occurring isoflavones, which have been studied for their potential health benefits. The mode of action of 4',7-Dimethoxyisoflavone involves modulating signaling pathways that are related to cellular growth and hormonal activity. It may influence pathways such as estrogen receptor signaling, although it possesses distinct properties compared to phytoestrogens found in soy products. Research into 4',7-Dimethoxyisoflavone explores its potential applications in sports science and medicine, primarily focusing on its ability to support muscle growth and recovery, as well as its potential anti-inflammatory and antioxidant effects. Scientists investigate this compound for its role in modulating metabolic processes, which could have implications for overall health and well-being. Studies continue to examine its precise biological effects, safety profile, and efficacy in various models to fully understand its utility in scientific and medical contexts.

Gallocatechin gallate is a flavonoid compound that can be isolated from the plant Gelsemium elegans and has antiviral activity.

Oxygen-heterocyclic compound

5-Methoxyflavanone is a synthetic flavonoid compound, which is derived from chemical modifications of naturally occurring flavonoids. These modifications often enhance bioavailability and activity compared to their natural counterparts. This compound functions primarily through its antioxidant activity, scavenging free radicals and reducing oxidative stress within biological systems. This mode of action is vital in cellular protection against damage caused by oxidative agents. 5-Methoxyflavanone has been widely studied for its potential applications in various scientific fields, particularly in pharmacology and biochemistry. Its abilities to modulate oxidative pathways make it a candidate for research into therapeutic interventions for diseases associated with oxidative stress, such as neurodegenerative disorders and chronic inflammatory conditions. Further exploration of its cellular interactions and efficacy in vivo can provide deeper insights into its role within biological systems and potential translational applications. Scientists are particularly interested in the compound's interactions at the molecular level to potentially develop novel therapeutic agents.

Isosinensetin is a polymethoxyflavone, which is a type of flavonoid compound. It is primarily sourced from citrus fruits, particularly those belonging to the genus Citrus, such as oranges and tangerines. The compound's mode of action is largely attributed to its various biochemical interactions, such as modulation of signaling pathways, antioxidant activity, and potential anti-inflammatory effects. These actions may influence cellular processes, contributing to its health-promoting properties. In scientific studies, isosinensetin has shown potential applications in a range of therapeutic areas. Its anti-inflammatory and antioxidant properties make it a candidate for research in chronic disease prevention and management. Moreover, its ability to modulate cellular signaling could provide insights into cancer research, where it might affect tumor growth and metastasis. While further studies are necessary to fully understand its mechanisms and efficacy, isosinensetin continues to be a compound of interest for researchers exploring natural products with health benefits.

Loureirin B is a natural polyphenolic compound, which is derived from the resin of Dracaena cochinchinensis, commonly known as Dragon's Blood. This compound exhibits its mode of action primarily through the inhibition of key inflammatory pathways, including the suppression of cyclooxygenase-2 (COX-2) and the reduction of pro-inflammatory cytokines. Such mechanisms suggest its potential in modulating inflammatory responses effectively. Loureirin B is utilized in various scientific investigations focused on its pharmacological potentials, particularly in the realms of anti-inflammatory and antioxidant research. Its applications extend to exploring therapeutic strategies for inflammatory diseases and conditions characterized by excessive oxidative stress. This compound is also of interest for its potential roles in vascular biology, including the modulation of platelet aggregation, thus presenting opportunities for the development of novel medical interventions.

Keracyanin chloride (Cyanidin 3-rutinoside chloride), an anthocyanin compound, exhibits antioxidant properties.