Sugars

Phenethyl glucosinolate potassium salt is a compound found in plants belonging to the Brassicaceae family. It has been shown to be highly toxic to larvae of the cabbage butterfly and other insects that feed on brassica plants. Phenethyl glucosinolate potassium salt has been shown to inhibit the development of these insects, probably by inhibiting protein synthesis in the insect's gut. The major sulfur-containing compound in this product is gluconasturtiin, which has been shown to inhibit growth of pekinensis at high temperatures. This compound also inhibits radiation-induced DNA damage and does not show significant effects on nonsignificant organisms such as yeast and mold.

Applications Labelled L-Glucose is the enantiomer of D-Glucose (G595000), a naturally occurring carbohydrate used in an abundance of cellular processes. L-Glucose is a synthetic sugar used in the formation of L-Glucose Pentaacetate (G596510), a potential therapeutic agent regarding type II diabetes. In addition, L-glucose can be used as a colon cleansing agent for before a colonoscopy procedure. References Malaisse, W. et al.: Int. J. Mol. Med., 2, 383 (1998); Raymer, G. et al.: Gastrointest. Endosc., 58, 30 (2003); Wang, R., et al.: J. Mol. Catal. B. Enz., 56, 131 (2009),

Applications beta-D-Glucopyranosylamine

Laricitrin-3,5'-di-O-glucoside is an organic compound that can be used as a research chemical. Laricitrin-3,5'-di-O-glucoside is a building block for the synthesis of other compounds and has been used in the synthesis of novel antibiotics. This compound is also a useful intermediate in the production of 3,6-dihydroxychalcone.

5-Fluorouridine Diphosphate Glucose (5-FdG-Glc) is a fluorinated analogue of uridine 5'-monophosphate. It is used as an analytical tool to study tumor metastases and to analyze the effects of different substances on the cell's metabolism. The enzyme activities of phosphatase and anabolic enzymes are potentiated by 5-FdG-Glc, which has been shown to be effective in inhibiting cancer cells and microorganisms. 5-FdG-Glc can also be used for the detection of p-nitrophenyl phosphate, which is a product of lipid peroxidation in cells.

Guanosine-2-Deoxy-2-Fluoro-D-Glucose Diphosphate Ester is a cell-free extract that inhibits the glycosylation of proteins. It is an analog of guanosine, which is a nucleotide and vitamin. The mechanism of action is through inhibition of the enzyme protein glycosylation, which prevents mannose from being converted to mannose phosphate. This inhibits the cycle that creates more sugar phosphates, which are needed for protein glycosylation. Guanosine-2-Deoxy-2-Fluoro-D-Glucose Diphosphate Ester has been shown to inhibit growth in cell culture at concentrations of 0.1 mM.

Applications N-Methoxy-N-methyl-β-D-glucopyranosylamine is used in the synthesis of 6-α-D-Glucopyranosyl Maltotriose (G419100), which is the sugar composition of sake. References Giri, N.Y., et al.: Arch. Biochem. Biophysics, 145, 505 (1971)