p53
Los inhibidores de p53 se dirigen a la proteína p53, un supresor tumoral que desempeña un papel crucial en la regulación del ciclo celular, la reparación del ADN y la apoptosis. Aunque p53 a menudo está mutado o inactivado en células cancerosas, su inhibición a veces es necesaria para proteger a las células sanas de la apoptosis durante ciertos tratamientos. Por otro lado, restaurar la función de p53 en los tumores puede conducir a la apoptosis de las células cancerosas. La investigación sobre inhibidores de p53 es compleja y significativa tanto para comprender los mecanismos del cáncer como para desarrollar nuevas terapias. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de p53 de alta calidad para apoyar su investigación en biología del cáncer, apoptosis y desarrollo terapéutico.
Productos de "p53"
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Anti-p53 Antibody (8M251)
Anti-p53 Antibody (8M251) is an antibody targeting p53. Anti-p53 Antibody (8M251) can be used in ELISA, WB, IHC, IF.Forma y color:Odour LiquidUNC0224
CAS:UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.Fórmula:C26H43N7O2Pureza:99.58%Forma y color:SolidPeso molecular:485.67Ref: TM-T17203
1mg51,00€2mg73,00€5mg97,00€10mg159,00€25mg354,00€50mg558,00€100mg797,00€500mg1.634,00€1mL*10mM (DMSO)107,00€HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Forma y color:Odour Lyophilized PowderXL177A
CAS:XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.Fórmula:C48H57ClN8O5Pureza:98.75%Forma y color:SolidPeso molecular:861.47Ref: TM-T9122
1mg96,00€5mg187,00€10mg298,00€25mg507,00€50mg730,00€100mg1.026,00€1mL*10mM (DMSO)283,00€Anti-Phospho-TP53 (Ser392) Antibody (7W136)
Anti-Phospho-TP53 (Ser392) Antibody (7W136) is an antibody targeting Phospho-TP53 (Ser392). Anti-Phospho-TP53 (Ser392) Antibody (7W136) can be used in ELISA, WB.Forma y color:Odour LiquidAnti-p53 Antibody (2H232)
Anti-p53 Antibody (2H232) is an antibody targeting p53. Anti-p53 Antibody (2H232) can be used in ELISA, IHC.Forma y color:Odour LiquidRezatapopt
CAS:Rezatapopt (PC14586) is a p53 reactivator with antitumor activity for the study of locally advanced or metastatic solid tumors.Fórmula:C28H31F4N5O2Pureza:98.12%Forma y color:SolidPeso molecular:545.57MT 63-78
CAS:MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).Fórmula:C21H14N2O2Pureza:97.11%Forma y color:SolidPeso molecular:326.35Anti-p53 Antibody (3K688)
Anti-p53 Antibody (3K688) is a Rabbit antibody targeting p53. Anti-p53 Antibody (3K688) can be used in WB,ELISA,IP.Forma y color:Odour LiquidAnti-p53 Antibody (8C308)
Anti-p53 Antibody (8C308) is an antibody targeting p53. Anti-p53 Antibody (8C308) can be used in ELISA, WB, IF, FCM.Forma y color:Odour LiquidNSC59984
CAS:NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.Fórmula:C12H15N3O4Pureza:99.18% - 99.59%Forma y color:SolidPeso molecular:265.27Ref: TM-T6910
5mg70,00€10mg107,00€25mg216,00€50mg354,00€100mg567,00€500mg1.198,00€1mL*10mM (DMSO)77,00€Anti-p53 Antibody (1J151)
Anti-p53 Antibody (1J151) is a Mouse antibody targeting p53. Anti-p53 Antibody (1J151) can be used in ELISA(Cap).Forma y color:Odour LiquidNSC-87877
CAS:NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.Fórmula:C19H13N3O7S2Pureza:97.35%Forma y color:SolidPeso molecular:459.45p53 (17-26)
CAS:Peptide is p53's amino acids 17-26, contacts Mdm-2 binding domain, also called p53N.Fórmula:C60H90N12O17Pureza:98%Forma y color:SolidPeso molecular:1251.43Anti-Phospho-TP53 (Thr55) Antibody (8C690)
Anti-Phospho-TP53 (Thr55) Antibody (8C690) is an antibody targeting Phospho-TP53 (Thr55). Anti-Phospho-TP53 (Thr55) Antibody (8C690) can be used in ELISA, WB, IF.Forma y color:Odour LiquidNutlin-3a
CAS:Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.Fórmula:C30H30Cl2N4O4Pureza:95.62% - 99.71%Forma y color:SolidPeso molecular:581.49Ref: TM-T6023
1mg49,00€2mg70,00€5mg96,00€10mg164,00€25mg268,00€50mg398,00€100mg587,00€1mL*10mM (DMSO)135,00€Chlorambucil
CAS:Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.Fórmula:C14H19Cl2NO2Pureza:97.37% - 98.45%Forma y color:Off-White Slightly Granular Powder Melting Point 65-69°CPeso molecular:304.21C16 Ceramide
CAS:C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it.Fórmula:C34H67NO3Pureza:99.00% - 99.92%Forma y color:White Crystalline SolidPeso molecular:537.9p53 Protein, Cynomolgus, Recombinant
p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family.Forma y color:Lyophilized PowderPeso molecular:43.7 kDa (predicted); 48 kDa (reducing conditions)Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Fórmula:C5H15N2O3PSPureza:99.88%Forma y color:White SolidPeso molecular:214.22
