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p53

p53

Los inhibidores de p53 se dirigen a la proteína p53, un supresor tumoral que desempeña un papel crucial en la regulación del ciclo celular, la reparación del ADN y la apoptosis. Aunque p53 a menudo está mutado o inactivado en células cancerosas, su inhibición a veces es necesaria para proteger a las células sanas de la apoptosis durante ciertos tratamientos. Por otro lado, restaurar la función de p53 en los tumores puede conducir a la apoptosis de las células cancerosas. La investigación sobre inhibidores de p53 es compleja y significativa tanto para comprender los mecanismos del cáncer como para desarrollar nuevas terapias. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de p53 de alta calidad para apoyar su investigación en biología del cáncer, apoptosis y desarrollo terapéutico.

Productos de "p53"

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productos por página.Hay 75 productos en esta categoría.
  • BIX-01294

    CAS:
    BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
    Fórmula:C28H38N6O2
    Pureza:99.31% - 99.64%
    Forma y color:Solid
    Peso molecular:490.64

    Ref: TM-T7697

    1mg
    40,00€
    2mg
    51,00€
    5mg
    85,00€
    10mg
    117,00€
    25mg
    207,00€
    50mg
    350,00€
    100mg
    518,00€
    200mg
    740,00€
    1mL*10mM (DMSO)
    131,00€
  • Anti-p53 Antibody (9G129)


    Anti-p53 Antibody (9G129) is a Rabbit antibody targeting p53. Anti-p53 Antibody (9G129) can be used in IHC-P,ICC/IF.
    Forma y color:Odour Liquid

    Ref: TM-TMAY-03856

    100µl
    277,00€
  • HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled


    p53 is a tumor suppressor protein.
    Forma y color:Odour Lyophilized Powder

    Ref: TM-TMPK-01437

    1mg
    17.643,00€
    100µg
    2.647,00€
  • SCH529074

    CAS:
    SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma.
    Fórmula:C31H36Cl2N6
    Pureza:98.71%
    Forma y color:Solid
    Peso molecular:563.56

    Ref: TM-T37042

    1mg
    35,00€
    2mg
    46,00€
    5mg
    64,00€
    10mg
    104,00€
    25mg
    220,00€
    50mg
    328,00€
    100mg
    469,00€
    1mL*10mM (DMSO)
    75,00€
  • Schisandrol B

    CAS:
    Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.
    Fórmula:C23H28O7
    Pureza:99.14% - 99.32%
    Forma y color:Solid
    Peso molecular:416.46

    Ref: TM-T6S1917

    5mg
    71,00€
    10mg
    96,00€
    25mg
    202,00€
    50mg
    303,00€
    100mg
    452,00€
    500mg
    1.035,00€
    1mL*10mM (DMSO)
    79,00€
  • CTX1

    CAS:
    CTX1 is a small molecule activator of p53.
    Fórmula:C14H10N4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:234.26

    Ref: TM-T15016

    25mg
    582,00€
    50mg
    757,00€
    100mg
    1.159,00€
  • PDK4-IN-1 hydrochloride

    CAS:
    PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).
    Fórmula:C22H20ClN3O2
    Pureza:99.54%
    Forma y color:Solid
    Peso molecular:393.87

    Ref: TM-T12412L

    1mg
    127,00€
    5mg
    300,00€
    10mg
    457,00€
    25mg
    750,00€
    50mg
    1.026,00€
    100mg
    1.406,00€
    500mg
    2.822,00€
    1mL*10mM (DMSO)
    329,00€
  • Etoposide

    CAS:
    Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).
    Fórmula:C29H32O13
    Pureza:99.19% - 99.94%
    Forma y color:Crystals From Methanol Solid
    Peso molecular:588.56

    Ref: TM-T0132

    50mg
    39,00€
    100mg
    52,00€
    500mg
    106,00€
    1mL*10mM (DMSO)
    55,00€
  • Anti-p53 Antibody (9G324)


    Anti-p53 Antibody (9G324) is an antibody targeting p53. Anti-p53 Antibody (9G324) can be used in ELISA, IF.
    Forma y color:Odour Liquid

    Ref: TM-TMAH-01203

    50µl
    213,00€
    100µl
    357,00€
  • Amifostine thiol dihydrochloride

    CAS:
    Amifostine (WR 1065) activates p53 via JNK and shields tissues from cancer drug toxicity.
    Fórmula:C5H16Cl2N2S
    Pureza:100%
    Forma y color:Solid
    Peso molecular:207.165

    Ref: TM-TQ0133

    5mg
    35,00€
    10mg
    52,00€
    25mg
    81,00€
    50mg
    A consultar
    1mL*10mM (DMSO)
    46,00€
  • BML-259

    CAS:
    BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.
    Fórmula:C14H16N2OS
    Pureza:99.68%
    Forma y color:Solid
    Peso molecular:260.35

    Ref: TM-T36964

    5mg
    50,00€
    10mg
    85,00€
    25mg
    169,00€
    50mg
    279,00€
    100mg
    487,00€
    500mg
    1.035,00€
    1mL*10mM (DMSO)
    52,00€
  • CT-1

    CAS:
    CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.
    Fórmula:C29H23F3N4O
    Pureza:99.24%
    Forma y color:Solid
    Peso molecular:500.51

    Ref: TM-T27093

    1mg
    115,00€
    5mg
    249,00€
    10mg
    368,00€
    25mg
    562,00€
    50mg
    787,00€
    100mg
    1.054,00€
    500mg
    A consultar
  • LLY-507

    CAS:
    LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.
    Fórmula:C36H42N6O
    Pureza:99.56% - 99.93%
    Forma y color:Solid
    Peso molecular:574.76

    Ref: TM-T6879

    1mg
    44,00€
    2mg
    55,00€
    5mg
    85,00€
    10mg
    138,00€
    25mg
    304,00€
    50mg
    552,00€
    100mg
    787,00€
    1mL*10mM (DMSO)
    110,00€
  • HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated


    p53 is a tumor suppressor protein.
    Forma y color:Odour Lyophilized Powder

    Ref: TM-TMPK-01552

    1mg
    5.293,00€
    100µg
    820,00€
  • (S)-10-Hydroxycamptothecin

    CAS:
    (S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
    Fórmula:C20H16N2O5
    Pureza:99.09% - 99.81%
    Forma y color:Solid
    Peso molecular:364.35

    Ref: TM-T2764

    25mg
    52,00€
    50mg
    66,00€
    100mg
    92,00€
    500mg
    187,00€
    1mL*10mM (DMSO)
    63,00€
  • HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)


    p53 is a tumor suppressor protein.
    Forma y color:Odour Lyophilized Powder

    Ref: TM-TMPK-01532

    1mg
    3.529,00€
    100µg
    547,00€
  • Leptomycin B

    CAS:
    Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.
    Fórmula:C33H48O6
    Pureza:99.04% - 99.71%
    Forma y color:White Crystalline Solid
    Peso molecular:540.73

    Ref: TM-T15735

    1mg
    202,00€
    2mg
    341,00€
    5mg
    620,00€
    10mg
    882,00€
    25mg
    1.320,00€
    50mg
    1.776,00€
    100mg
    2.403,00€
    1mL*10mM (DMSO)
    283,00€
  • SLMP53-1

    CAS:
    SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migration
    Fórmula:C20H18N2O2
    Pureza:99.64%
    Forma y color:Solid
    Peso molecular:318.37

    Ref: TM-T60839

    1mg
    126,00€
    5mg
    298,00€
    10mg
    487,00€
    25mg
    938,00€
    50mg
    1.568,00€
    100mg
    2.517,00€
    1mL*10mM (DMSO)
    35,00€
  • NSC 66811

    CAS:
    NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.
    Fórmula:C23H20N2O
    Pureza:96.94%
    Forma y color:Solid
    Peso molecular:340.42

    Ref: TM-T21578

    5mg
    46,00€
    10mg
    62,00€
    25mg
    90,00€
    50mg
    135,00€
    100mg
    195,00€
    200mg
    284,00€
    1mL*10mM (DMSO)
    49,00€
  • NSC 146109 hydrochloride

    CAS:
    NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.
    Fórmula:C17H17ClN2S
    Pureza:97.03%
    Forma y color:Solid
    Peso molecular:316.85

    Ref: TM-T12257

    5mg
    40,00€
    10mg
    59,00€
    1mL*10mM (DMSO)
    46,00€