p53
Los inhibidores de p53 se dirigen a la proteína p53, un supresor tumoral que desempeña un papel crucial en la regulación del ciclo celular, la reparación del ADN y la apoptosis. Aunque p53 a menudo está mutado o inactivado en células cancerosas, su inhibición a veces es necesaria para proteger a las células sanas de la apoptosis durante ciertos tratamientos. Por otro lado, restaurar la función de p53 en los tumores puede conducir a la apoptosis de las células cancerosas. La investigación sobre inhibidores de p53 es compleja y significativa tanto para comprender los mecanismos del cáncer como para desarrollar nuevas terapias. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de p53 de alta calidad para apoyar su investigación en biología del cáncer, apoptosis y desarrollo terapéutico.
Productos de "p53"
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UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Fórmula:C27H45N7O3Pureza:99.25%Forma y color:SolidPeso molecular:515.69O6-Benzylguanine
CAS:O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.Fórmula:C12H11N5OPureza:98.90%Forma y color:Solid CrystallinePeso molecular:241.25BMH-7 HCl
BMH-7 HCl is a p53 activator, showing anti-cancer activity by activating the p53 pathway.Fórmula:C20H22ClN5OForma y color:SolidPeso molecular:383.88BAY 1892005
CAS:BAY 1892005 is a p53 protein modulator that targets the p53 condenser for the study of diseases associated with misfolded p53 proteinFórmula:C11H8ClFN2OSPureza:99.62%Forma y color:SoildPeso molecular:270.71BMH-7
CAS:BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.Fórmula:C20H21N5OPureza:99.71%Forma y color:SolidPeso molecular:347.41HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Forma y color:Odour Lyophilized PowderPifithrin-α, p-Nitro, Cyclic
CAS:Pifithrin-α, p-Nitro, Cyclic (PFN-α) (PFN-α) is cell-permeable and active-form inhibitor of p53.Fórmula:C15H13N3O2SPureza:99.43%Forma y color:SolidPeso molecular:299.35Ref: TM-T12472
1mg40,00€2mg52,00€5mg88,00€10mg126,00€25mg250,00€50mg406,00€100mg607,00€1mL*10mM (DMSO)87,00€Theaflavin 3,3'-digallate
CAS:Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancerFórmula:C43H32O20Pureza:98.71% - 99.86%Forma y color:SolidPeso molecular:868.7BIX-01294 trihydrochloride
CAS:BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Fórmula:C28H38N6O2·3HClPureza:99.41% - 99.95%Forma y color:SolidPeso molecular:600.02Ref: TM-T1959
1mg44,00€2mg55,00€5mg71,00€10mg107,00€25mg192,00€50mg274,00€100mg492,00€500mg1.103,00€1mL*10mM (DMSO)139,00€Anti-Phospho-TP53 (Ser9) Antibody (4M602)
Anti-Phospho-TP53 (Ser9) Antibody (4M602) is an antibody targeting Phospho-TP53 (Ser9). Anti-Phospho-TP53 (Ser9) Antibody (4M602) can be used in ELISA, IF.Forma y color:Odour LiquidMethylstat
CAS:Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability.Fórmula:C28H31N3O6Pureza:98.34% - 98.34%Forma y color:SolidPeso molecular:505.56Anti-Phospho-TP53 (Ser33) Antibody (4K787)
Anti-Phospho-TP53 (Ser33) Antibody (4K787) is an antibody targeting Phospho-TP53 (Ser33). Anti-Phospho-TP53 (Ser33) Antibody (4K787) can be used in ELISA, IHC, IF.Forma y color:Odour LiquidZMC1
CAS:NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).Fórmula:C11H14N4SPureza:97.48% - 98.97%Forma y color:SolidPeso molecular:234.32HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
p53 is a tumor suppressor protein.Forma y color:Odour Lyophilized PowderHLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
p53 is a tumor suppressor protein.Forma y color:Odour Lyophilized Powder
