Caspasa
Los inhibidores de caspasas son compuestos que bloquean la actividad de las caspasas, una familia de proteasas que son ejecutores centrales de la apoptosis. Las caspasas escinden sustratos específicos dentro de la célula para desencadenar el proceso apoptótico, lo que conduce a la muerte celular programada. Los inhibidores de caspasas se utilizan para estudiar los mecanismos de la apoptosis, así como para prevenir la muerte celular no deseada en varios modelos de investigación. Estos inhibidores también se exploran en contextos terapéuticos para proteger las células de la apoptosis en enfermedades como la neurodegeneración. En CymitQuimica, ofrecemos una amplia gama de inhibidores de caspasas de alta calidad para apoyar su investigación en apoptosis, muerte celular y campos relacionados.
Productos de "Caspasa"
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PQ401
CAS:PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).Fórmula:C18H16ClN3O2Pureza:99.13%Forma y color:SolidPeso molecular:341.79Penicillic acid
CAS:Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.Fórmula:C8H10O4Pureza:98%Forma y color:Needles From Petroleum Ether Slight Yellow PowderPeso molecular:170.16Brazilein
CAS:Brazilein, a natural antioxidant, inhibits adipocyte differentiation by inhibiting PPAR γ induction, inhibits skin cancer cells through increasing caspase-3 .Fórmula:C16H12O5Forma y color:SolidPeso molecular:284.26Taurodeoxycholic acid sodium hydrate
CAS:Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.Fórmula:C26H46NNaO7SPureza:98.87%Forma y color:SolidPeso molecular:539.70Crustecdysone
CAS:Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.Fórmula:C27H44O7Pureza:96.31% - 99.06%Forma y color:Canary Yellow Fine PowderPeso molecular:480.63Raptinal
CAS:Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.Fórmula:C28H18O2Pureza:≥98%Forma y color:SolidPeso molecular:386.44Ref: TM-T38563
1mg40,00€5mg88,00€10mg113,00€25mg180,00€50mg265,00€100mg393,00€200mg585,00€1mL*10mM (DMSO)87,00€PAC-1
CAS:PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Fórmula:C23H28N4O2Pureza:96.78% - 99.77%Forma y color:SolidPeso molecular:392.49J22352
CAS:J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects inFórmula:C24H21N3O4Forma y color:SolidPeso molecular:415.44Caspase-3-IN-2
CAS:Caspase-3-IN-2 (Compound 4d) acts as an inhibitor of α-Chymotrypsin. It also exhibits inhibitory activity against HIV protease and caspase 3, with inhibition rates of 57% and 51% respectively at a concentration of 100 μM.Fórmula:C10H6ClNO5Forma y color:SolidPeso molecular:255.6115,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Fórmula:C18H16O5Pureza:97.53%Forma y color:SolidPeso molecular:312.32Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Fórmula:C26H45NO6SPureza:98.12% - 99.93%Forma y color:White SolidPeso molecular:499.7ZIF-8
CAS:ZIF-8 is an anticancer agent that can inherently trigger pyroptosis through a caspase-1/gasdermin D (GSDMD)-dependent pathway.Fórmula:C4H6N2ZnForma y color:SolidPeso molecular:147.5135,7-Dihydroxychromone
CAS:1.Fórmula:C9H6O4Pureza:99.73% - ≥95%Forma y color:SolidPeso molecular:178.14Ref: TM-T5S1805
1mg47,00€5mg88,00€10mg126,00€25mg208,00€50mg309,00€100mg462,00€500mg1.008,00€1mL*10mM (DMSO)80,00€Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Fórmula:C21H28O2Pureza:99.40% - 99.8%Forma y color:Light Yellow PowderPeso molecular:312.45Ref: TM-T5574
1mg35,00€5mg55,00€10mg93,00€25mg178,00€50mg245,00€100mg360,00€200mg532,00€1mL*10mM (DMSO)60,00€Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Fórmula:C8H12ClNO3Pureza:96.17% - 99.85%Forma y color:Physical Description Beige Solid (Ntp 1992)Peso molecular:205.64Belnacasan
CAS:Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Fórmula:C24H33ClN4O6Pureza:96.53% - 99.5%Forma y color:SolidPeso molecular:508.99Ref: TM-T6090
2mg37,00€5mg50,00€10mg86,00€25mg170,00€50mg235,00€100mg419,00€200mg617,00€1mL*10mM (DMSO)56,00€CZL55
CAS:CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Fórmula:C20H22N2O6Pureza:98.19%Forma y color:SolidPeso molecular:386.4Z-LEVD-FMK
CAS:Z-LEVD-FMK is a caspase-4 inhibitor with anti-cancer activity, capable of eliminating LPS-induced GCLC protein degradation.Fórmula:C31H45FN4O10Forma y color:SolidPeso molecular:652.71Lacidipine
CAS:Lacidipine (SN-305) is a slow-acting, long-duration lipophilic dihydropyridine calcium blocker that prevents reflex tachycardia and lowers blood pressure.Fórmula:C26H33NO6Pureza:99.98%Forma y color:White-To-Off-White Crystalline SolidPeso molecular:455.54Senkyunolide I
CAS:1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.Fórmula:C12H16O4Pureza:99.73% - 99.88%Forma y color:SolidPeso molecular:224.25Ref: TM-T5S2076
1mg48,00€5mg93,00€10mg123,00€25mg188,00€50mg283,00€100mg437,00€500mg938,00€1mL*10mM (DMSO)89,00€
