Caspasa
Los inhibidores de caspasas son compuestos que bloquean la actividad de las caspasas, una familia de proteasas que son ejecutores centrales de la apoptosis. Las caspasas escinden sustratos específicos dentro de la célula para desencadenar el proceso apoptótico, lo que conduce a la muerte celular programada. Los inhibidores de caspasas se utilizan para estudiar los mecanismos de la apoptosis, así como para prevenir la muerte celular no deseada en varios modelos de investigación. Estos inhibidores también se exploran en contextos terapéuticos para proteger las células de la apoptosis en enfermedades como la neurodegeneración. En CymitQuimica, ofrecemos una amplia gama de inhibidores de caspasas de alta calidad para apoyar su investigación en apoptosis, muerte celular y campos relacionados.
Productos de "Caspasa"
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Sarglaroids F
Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+Fórmula:C38H44O12Pureza:98%Forma y color:SolidPeso molecular:692.75Z-VAD(OMe)-FMK
CAS:View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.Fórmula:C22H30FN3O7Pureza:95.92% - 99.44%Forma y color:SolidPeso molecular:467.49Ref: TM-T6013
1mg57,00€2mg88,00€5mg144,00€10mg235,00€25mg349,00€50mg472,00€100mg658,00€200mg933,00€1mL*10mM (DMSO)145,00€KEA1-97
CAS:Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).Fórmula:C15H9Cl2FN4Pureza:98.7%Forma y color:SolidPeso molecular:335.16Q-VD-OPH
CAS:Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.Fórmula:C26H25F2N3O6Pureza:97.8% - 98.95%Forma y color:SolidPeso molecular:513.5Licochalcone A
CAS:Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects.Fórmula:C21H22O4Pureza:98.11% - 98.96%Forma y color:White Crystalline PowderPeso molecular:338.4Dihydrocapsaicin
CAS:Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Fórmula:C18H29NO3Pureza:99.61% - ≥95%Forma y color:White CrystalPeso molecular:307.43Z-FA-FMK
CAS:Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.Fórmula:C21H23FN2O4Pureza:99.43% - 99.68%Forma y color:SolidPeso molecular:386.42Ac-DEVD-CHO acetate
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.Fórmula:C22H34N4O13Pureza:98.54%Forma y color:SolidPeso molecular:562.52PHYTOSPHINGOSINE
CAS:Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.Fórmula:C18H39NO3Pureza:99.53%Forma y color:SolidPeso molecular:317.51Z-VAD-FMK
CAS:Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does notFórmula:C21H28FN3O7Pureza:98.24% - 99.79%Forma y color:SolidPeso molecular:453.46Ref: TM-T7020
1mg118,00€5mg245,00€10mg416,00€25mg662,00€50mg939,00€100mg1.264,00€200mg1.691,00€1mL*10mM (DMSO)269,00€Z-DEVD-FMK
CAS:Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,Fórmula:C30H41FN4O12Pureza:96.19% - 99.69%Forma y color:SolidPeso molecular:668.66Almorexant
CAS:Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Fórmula:C29H31F3N2O3Pureza:97.75% - 98.02%Forma y color:SolidPeso molecular:512.56Ac-DEVD-AMC
CAS:Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .Fórmula:C30H37N5O13Pureza:98.20%Forma y color:White PowderPeso molecular:675.6415-Acetoxyscirpenol
CAS:15-acetoxyscirpenol: ASM that induces apoptosis, inhibits Jurkat T cell growth dose-dependently, and activates caspases other than caspase-3.Fórmula:C17H24O6Pureza:98%Forma y color:SolidPeso molecular:324.373ZYZ-488
CAS:ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.Fórmula:C20H29N3O11Pureza:99.04%Forma y color:SolidPeso molecular:487.46Ac-VAD-CHO
CAS:Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release ofFórmula:C14H23N3O6Pureza:98%Forma y color:SolidPeso molecular:329.35Emricasan
CAS:Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.Fórmula:C26H27F4N3O7Pureza:98.13% - 99%Forma y color:SolidPeso molecular:569.5Ref: TM-T6826
1mg44,00€2mg58,00€5mg95,00€10mg144,00€25mg254,00€50mg419,00€100mg617,00€1mL*10mM (DMSO)107,00€Duocarmycin A
CAS:Duocarmycin A: an antitumor DNA alkylator targeting adenine; induces apoptosis in HLC-2 cells.Fórmula:C26H25N3O8Pureza:98%Forma y color:SolidPeso molecular:507.49Z-YVAD-FMK
CAS:AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.Fórmula:C31H39FN4O9Pureza:98.00%Forma y color:SolidPeso molecular:630.66Ac-VEID-AFC
Ac-VEID-AFC is a fluorogenic substrate for caspase-6, utilized in caspase-6 activity assays [1].Fórmula:C32H39F3N4O12Pureza:98%Forma y color:SolidPeso molecular:728.67
