Caspasa
Los inhibidores de caspasas son compuestos que bloquean la actividad de las caspasas, una familia de proteasas que son ejecutores centrales de la apoptosis. Las caspasas escinden sustratos específicos dentro de la célula para desencadenar el proceso apoptótico, lo que conduce a la muerte celular programada. Los inhibidores de caspasas se utilizan para estudiar los mecanismos de la apoptosis, así como para prevenir la muerte celular no deseada en varios modelos de investigación. Estos inhibidores también se exploran en contextos terapéuticos para proteger las células de la apoptosis en enfermedades como la neurodegeneración. En CymitQuimica, ofrecemos una amplia gama de inhibidores de caspasas de alta calidad para apoyar su investigación en apoptosis, muerte celular y campos relacionados.
Productos de "Caspasa"
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Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Fórmula:C19H24O5Pureza:96.66%Forma y color:SolidPeso molecular:332.39Diclofenac Potassium
CAS:Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.Fórmula:C14H10Cl2KNO2Pureza:99.51%Forma y color:White To Yellowish Crystalline PowderPeso molecular:334.24Diclofenac diethylamine
CAS:Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).Fórmula:C18H22Cl2N2O2Pureza:99.81% - 99.87%Forma y color:SolidPeso molecular:369.29Z-IETD-FMK
CAS:Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.Fórmula:C30H43FN4O11Pureza:95% - 99.81%Forma y color:SolidPeso molecular:654.68Ref: TM-T7019
1mg125,00€2mg182,00€5mg263,00€10mg420,00€25mg682,00€50mgA consultar1mL*10mM (DMSO)408,00€(2R,3S)-Emricasan
CAS:(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan. This compound acts as an orally effective irreversible pan-caspase inhibitor. (2R,3S)-Emricasan inhibits the increase in caspase-3 activity induced by Zika virus (ZIKV) and protects human cortical neural progenitor cells.Fórmula:C26H27F4N3O7Forma y color:SolidPeso molecular:569.5Boc-Asp(OMe)-fluoromethyl ketone
CAS:Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.Fórmula:C11H18FNO5Pureza:≥98%Forma y color:SolidPeso molecular:263.26M190S
CAS:M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Fórmula:C21H21N5O2Pureza:98%Forma y color:SolidPeso molecular:375.42Ivachtin
CAS:Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remainingFórmula:C20H21N3O7SPureza:98.17%Forma y color:SolidPeso molecular:447.46Anisperimus
CAS:Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.Fórmula:C18H39N7O3Pureza:98.10%Forma y color:SolidPeso molecular:401.55ML-9
CAS:ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Fórmula:C15H18Cl2N2O2SPureza:99.69%Forma y color:Crystalline SolidPeso molecular:361.29Cystamine
CAS:Cystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM.Fórmula:C4H12N2S2Pureza:99.41%Forma y color:SolidPeso molecular:152.28Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Fórmula:C16H10O7Pureza:98.07% - 99.76%Forma y color:SolidPeso molecular:314.25Ref: TM-T3384
1mg35,00€5mg74,00€10mg115,00€25mg185,00€50mg331,00€100mg437,00€500mg1.008,00€1mL*10mM (DMSO)52,00€Z-VEID-AFC
CAS:Z-VEID-AFC is a caspase-6 fluorescent substrate [1].Fórmula:C38H44F3N5O12Pureza:98%Forma y color:SolidPeso molecular:819.78TC11
CAS:TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosisFórmula:C20H22N2O2Pureza:97.86%Forma y color:SolidPeso molecular:322.4Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Fórmula:C8H12BrNO3Pureza:98.1% - 99.88%Forma y color:Beige To Brown Fine Crystalline PowderPeso molecular:250.09Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14Aristolactam I
CAS:Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.Fórmula:C17H11NO4Pureza:98.98% - 99.63%Forma y color:SolidPeso molecular:293.27Ref: TM-T3S1227
1mg60,00€5mg140,00€10mg216,00€25mg369,00€50mg545,00€100mg775,00€1mL*10mM (DMSO)175,00€AKN-028
CAS:AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.Fórmula:C17H14N6Pureza:97.3%Forma y color:SolidPeso molecular:302.33CIL62
CAS:CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].Fórmula:C23H26O5Pureza:97.07%Forma y color:SolidPeso molecular:382.45Ref: TM-T8468
1mg52,00€5mg116,00€10mg170,00€25mg335,00€50mg562,00€100mg758,00€200mg1.017,00€1mL*10mM (DMSO)128,00€
