Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Productos de "Cromatina / Epigenética"
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MZ 1
CAS:MZ 1 is a BRD4 protein degrader based on PROTAC technology.Fórmula:C49H60ClN9O8S2Pureza:99.31%Forma y color:SolidPeso molecular:1002.64Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Fórmula:C23H25ClFN7OPureza:99.33% - 99.86%Forma y color:SolidPeso molecular:469.94Ref: TM-T2638
5mg51,00€10mg88,00€25mg160,00€50mg296,00€100mg469,00€500mg1.035,00€1mL*10mM (DMSO)57,00€JAK2-IN-7
CAS:JAK2-IN-7 selectively inhibits JAK2 (IC50: 3 nM), shows 14-fold selectivity over JAK1/3, FLT3, induces G0/G1 arrest, apoptosis, and has antitumor effects.Fórmula:C26H33N7OPureza:98.71%Forma y color:SolidPeso molecular:459.59Ref: TM-T35900
1mg145,00€5mg354,00€10mg630,00€25mg1.301,00€50mg1.738,00€100mg2.357,00€1mL*10mM (DMSO)358,00€AZ-3
CAS:AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).Fórmula:C20H28FN7Pureza:98%Forma y color:SolidPeso molecular:385.48JAK-IN-28
CAS:JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].Fórmula:C20H18ClN7OPureza:98%Forma y color:SolidPeso molecular:407.86AMI-1
CAS:AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).Fórmula:C21H14N2Na2O9S2Pureza:97.53% - 99.9%Forma y color:DrypowderPeso molecular:548.45Eicosapentaenoic Acid
CAS:Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms.Fórmula:C20H30O2Pureza:96.20%Forma y color:LiquidPeso molecular:302.45Menin-MLL inhibitor MI-2
CAS:Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.Fórmula:C18H25N5S2Pureza:97.46%Forma y color:SolidPeso molecular:375.55Ref: TM-T2649
2mg42,00€5mg62,00€10mg88,00€25mg169,00€50mg243,00€100mg376,00€200mg550,00€1mL*10mM (DMSO)67,00€MS436
CAS:MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.Fórmula:C18H17N5O3SPureza:97.95% - 98.92%Forma y color:SolidPeso molecular:383.42Ref: TM-T1854
2mg44,00€5mg65,00€10mg103,00€25mg192,00€50mg344,00€100mg505,00€500mg1.093,00€1mL*10mM (DMSO)72,00€MBM-17S
CAS:MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest andFórmula:C36H40N6O10Pureza:98%Forma y color:SolidPeso molecular:716.74SF2523
CAS:SF2523 is a highly selective and potent inhibitor.Fórmula:C19H17NO5SPureza:97.78% - 98.06%Forma y color:SolidPeso molecular:371.41Ref: TM-T3986
1mg37,00€5mg79,00€10mg119,00€25mg274,00€50mg432,00€100mg638,00€500mg1.359,00€1mL*10mM (DMSO)87,00€MI-2-2
CAS:MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.Fórmula:C17H20F3N5S2Pureza:99.56%Forma y color:SolidPeso molecular:415.5BCI-121
CAS:BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.Fórmula:C14H18BrN3O2Pureza:99.67%Forma y color:SolidPeso molecular:340.22Belzutifan
CAS:"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."Fórmula:C17H12F3NO4SPureza:99.34% - 99.41%Forma y color:SolidPeso molecular:383.34Ref: TM-T16679
1mg70,00€5mg153,00€10mg216,00€25mg411,00€50mg660,00€100mg938,00€200mg1.264,00€1mL*10mM (DMSO)166,00€ACBI1
CAS:ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50sFórmula:C49H58FN9O7SPureza:97.54% - 98.15%Forma y color:SolidPeso molecular:936.1SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Fórmula:C20H27ClN8OSPureza:98.29%Forma y color:SolidPeso molecular:463Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Fórmula:C26H30N4O5SPureza:99.09%Forma y color:SolidPeso molecular:510.61Ref: TM-T9497
5mg60,00€10mg87,00€25mg117,00€50mg144,00€100mg216,00€200mg325,00€500mg545,00€1mL*10mM (DMSO)77,00€HIF-2α agonist 2
CAS:HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α.Fórmula:C13H8Br2N2O2SPureza:98.32%Forma y color:SoildPeso molecular:416.09NCD38 TFA
NCD38 TFA serves as a selective inhibitor of LSD1 [1] [2].Fórmula:C37H37ClF3N3O4Pureza:98%Forma y color:SolidPeso molecular:680.16L002
CAS:L002 is a potent inhibitor of acetyltransferase p300 with an IC50 of 1.98 μM, blocking histone and p53 acetylation, and may treat cardiac hypertrophy.Fórmula:C15H15NO5SPureza:98.59%Forma y color:SolidPeso molecular:321.35
