NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Productos de "NF-κB"
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PROTAC IRAK4 ligand-4
CAS:PROTAC IRAK4 ligand-4, a Ligand for Target Protein for PROTAC (Ligand for Target Protein for PROTAC), exhibits anti-tumor activity and is utilized in synthesizing PROTAC IRAK4 degrader-12. This compound serves as a targeted ligand with specific applications in the development of cancer therapeutics.Fórmula:C24H26F2N6O3Forma y color:SolidPeso molecular:484.5INF 195
CAS:INF 195 is an inflammasome NLRP3 inhibitor that can be used to study myocardial ischemia and myocardial infarction.Fórmula:C17H22ClNO3Pureza:99.78%Forma y color:SoildPeso molecular:323.81Stachydrine Hydrochloride
CAS:Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.Fórmula:C7H14ClNO2Pureza:99.53% - 99.71%Forma y color:Light Yellow PastePeso molecular:179.64Vanillic Acid
CAS:Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.Fórmula:C8H8O4Pureza:99.82%Forma y color:White Odourless Crystals Or PowderPeso molecular:168.15Indacaterol maleate
CAS:Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.Fórmula:C28H32N2O7Pureza:99.03% - 99.67%Forma y color:SolidPeso molecular:508.56Anti-inflammatory agent 51
CAS:Anti-inflammatory agent 51 amide/sulfonamide anti-inflammatory and anti-tumor activity inhibition of NF-κB activation acute lung injury and ulcerative colitis.Fórmula:C22H22N6O6SPureza:99.46%Forma y color:SoildPeso molecular:498.512-Hydroxychalcone
CAS:2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Fórmula:C15H12O2Pureza:99.60%Forma y color:SolidPeso molecular:224.25Maslinic acid
CAS:Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.Fórmula:C30H48O4Pureza:98.1% - 99.98%Forma y color:SolidPeso molecular:472.7Guaiacol
CAS:Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.Fórmula:C7H8O2Pureza:99.83%Forma y color:Colourless To Pale Yellow Solid CrystallinePeso molecular:124.14ZB-R-55
CAS:ZB-R-55 is an oral and highly potent bimodal RIPK1 inhibitor with excellent kinase selectivity in lps-induced sepsis models for the study of SIRS and sepsis.Fórmula:C25H23N5O3Pureza:98.26%Forma y color:SolidPeso molecular:441.48Sinomenine
CAS:Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.Fórmula:C19H23NO4Pureza:99.02% - 99.89%Forma y color:White PowderPeso molecular:329.39Karacoline
CAS:Karacolinem: natural compound, inhibits ECM breakdown in IDD through NF-κB pathway.Fórmula:C22H35NO4Pureza:99.64% - 99.75%Forma y color:SolidPeso molecular:377.52Urolithin B
CAS:Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFórmula:C13H8O3Pureza:99.45%Forma y color:SolidPeso molecular:212.2Selnoflast
CAS:Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of coronary arteries and ulcerative colitis.Fórmula:C20H29N3O3SPureza:100% - 99.82%Forma y color:SolidPeso molecular:391.53Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Fórmula:C38H44N2O6Pureza:98.81% - 99.18%Forma y color:SolidPeso molecular:624.77anemarsaponin B
CAS:Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activityFórmula:C45H74O18Pureza:99.06% - 99.81%Forma y color:SolidPeso molecular:903.06(S)-(+)-Ibuprofen
CAS:(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).Fórmula:C13H18O2Pureza:99.51% - 99.86%Forma y color:Colourless Crystalline SolidPeso molecular:206.28GSK2982772
CAS:GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.Fórmula:C20H19N5O3Pureza:99.27% - 99.31%Forma y color:SolidPeso molecular:377.4Bay 65-1942 free base
CAS:Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.Fórmula:C22H25N3O4Pureza:98%Forma y color:SolidPeso molecular:395.45HOMOPLANTAGININ
CAS:Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and showsFórmula:C22H22O11Pureza:97.63% - 99.66%Forma y color:SolidPeso molecular:462.4Ref: TM-T4S0217
5mg50,00€10mg74,00€25mg140,00€50mg226,00€100mg324,00€200mg464,00€1mL*10mM (DMSO)52,00€
