CXCR
Los CXCR son una subfamilia de GPCR que se unen a quimiocinas, pequeñas proteínas de señalización que guían el movimiento de las células inmunitarias hacia los sitios de inflamación, infección o lesión. Los CXCR desempeñan roles cruciales en las respuestas inmunitarias, la metástasis del cáncer y las enfermedades inflamatorias. Los moduladores de CXCR se están investigando por su potencial en el tratamiento de enfermedades autoinmunes, cáncer y afecciones inflamatorias crónicas. En CymitQuimica, ofrecemos una gama de moduladores de CXCR de alta calidad para apoyar su investigación en inmunología, oncología e inflamación.
Productos de "CXCR"
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AZD-5069
CAS:AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).Fórmula:C18H22F2N4O5S2Pureza:98.38% - 98.63%Forma y color:SolidPeso molecular:476.52Ref: TM-T7681
1mg50,00€2mg65,00€5mg85,00€10mg124,00€25mg227,00€50mg350,00€100mg522,00€500mg1.130,00€1mL*10mM (DMSO)88,00€AZD8797
CAS:AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents nociceptive hypersensitivity in rats.Fórmula:C19H25N5OS2Pureza:98.73% - 99.68%Forma y color:SolidPeso molecular:403.56Ref: TM-T14384
1mg90,00€5mg188,00€10mg354,00€25mg748,00€50mg938,00€100mg1.359,00€1mL*10mM (DMSO)216,00€ML339
CAS:ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.Fórmula:C26H32ClN3O5Pureza:99.46%Forma y color:SolidPeso molecular:502SCH 546738
CAS:SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development of autoimmune diseases and delays graft rejection.Fórmula:C23H31Cl2N7OPureza:98.67%Forma y color:SolidPeso molecular:492.45Danirixin
CAS:Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).Fórmula:C19H21ClFN3O4SPureza:100.00% - 99.78%Forma y color:SolidPeso molecular:441.9SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Fórmula:C18H23F2N5O4S2Pureza:99.65% - 99.92%Forma y color:SolidPeso molecular:475.53USL311
CAS:USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Fórmula:C24H34N6OPureza:98.46% - 99.56%Forma y color:SolidPeso molecular:422.57Ref: TM-T17208
1mg42,00€5mg88,00€10mg127,00€25mg250,00€50mg393,00€100mg628,00€500mg1.304,00€1mL*10mM (DMSO)87,00€UNBS5162
CAS:UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.Fórmula:C17H18N4O3Pureza:98.37% - 99.97%Forma y color:SolidPeso molecular:326.35Ref: TM-T2477
1mg39,00€5mg81,00€10mg116,00€25mg215,00€50mg340,00€100mg540,00€200mg787,00€1mL*10mM (DMSO)89,00€ATI-2341
CAS:ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.Fórmula:C104H178N26O25S2Forma y color:SolidPeso molecular:2256.82Nicotinamide N-oxide
CAS:Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme xanthine oxidase.Fórmula:C6H6N2O2Pureza:99.61% - 99.9%Forma y color:SolidPeso molecular:138.12WZ811
CAS:WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).Fórmula:C18H18N4Pureza:99.42% - ≥95%Forma y color:SolidPeso molecular:290.36Plerixafor octahydrochloride
CAS:Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.Fórmula:C28H62Cl8N8Pureza:98.01% - 99.79%Forma y color:SolidPeso molecular:794.46AMD-070 hydrochloride
CAS:AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.Fórmula:C21H28ClN5Pureza:98.38% - 98.57%Forma y color:SolidPeso molecular:385.93(R)-SCH 546738
CAS:(R)-SCH 546738, the R-isomer of SCH 546738, is a non-competitive, orally active antagonist targeting the CXCR3 receptor, exhibiting a K_i of 0.4 nM for the human CXCR3 receptor.Fórmula:C23H31Cl2N7OForma y color:SolidPeso molecular:492.45CCX662
CAS:CCX662 is a CXCR7 antagonist. It inhibits the binding of 125I-CXCL12 to CXCR7 with an IC50 of 9 nM. This compound is suitable for use in cancer research.Fórmula:C28H37N5O4SForma y color:SolidPeso molecular:539.69JMS-17-2
CAS:JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).Fórmula:C25H26ClN3OPureza:98.70% - 99.44%Forma y color:SolidPeso molecular:419.95Ref: TM-T5849
1mg40,00€2mg52,00€5mg87,00€10mg131,00€25mg221,00€50mg344,00€100mg512,00€1mL*10mM (DMSO)96,00€Mavorixafor
CAS:Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding.Fórmula:C21H27N5Pureza:98.56%Forma y color:SolidPeso molecular:349.47Ref: TM-TQ0174
1mg70,00€2mg92,00€5mg153,00€10mg220,00€25mg396,00€50mg588,00€100mg835,00€1mL*10mM (DMSO)249,00€Burixafor hydrobromide
CAS:Burixafor hydrobromide is an oral CXCR4 blocker with anti-angiogenic properties, potentially treating choroid neovascularization.Fórmula:C27H52BrN8O3PPureza:98%Forma y color:SolidPeso molecular:647.644MSX-130
CAS:MSX-130 is CXCR4 Antagonist.Fórmula:C36H26N4Pureza:99.19%Forma y color:SolidPeso molecular:514.62Delmetacin
CAS:Delmetacin: a non-steroidal anti-inflammatory drug with analgesic properties, inhibits CXCR1.Fórmula:C18H15NO3Pureza:99.42%Forma y color:SolidPeso molecular:293.32
