TLR
Los receptores tipo Toll (TLR) son una clase de proteínas que desempeñan un papel crítico en el sistema inmunitario innato al reconocer patrones moleculares asociados a patógenos (PAMP) e iniciar respuestas inmunitarias. Los TLR están involucrados en la detección de una amplia gama de patógenos, incluidos bacterias, virus y hongos, y son esenciales para la activación de las vías de señalización inflamatorias. La desregulación de la señalización de los TLR se asocia con enfermedades inflamatorias crónicas, trastornos autoinmunes y cáncer. En CymitQuimica, ofrecemos una variedad de moduladores de TLR de alta calidad para apoyar su investigación en inmunidad innata, inflamación y enfermedades infecciosas.
Productos de "TLR"
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MD2-TLR4-IN-1
CAS:MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.Fórmula:C22H14Cl2N4OPureza:97.74%Forma y color:SolidPeso molecular:421.28Ref: TM-T7672
1mg62,00€5mg135,00€10mg212,00€25mg363,00€50mg510,00€100mg672,00€200mg905,00€1mL*10mM (DMSO)149,00€TLR3-IN-1
CAS:TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor. It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the TNF-α and IL-1β.Fórmula:C18H13ClFNO3SPureza:98.56%Forma y color:SolidPeso molecular:377.82Ref: TM-T22698
1mg52,00€2mg74,00€5mg114,00€10mg187,00€25mg398,00€50mg593,00€100mg845,00€500mg1.700,00€1mL*10mM (DMSO)126,00€MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Conjugate
CAS:MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Conjugate is a conjugate formed by linking MC-Val-Cit-PAB-Amide and TLR7 agonist 4, useful for cancer research.Fórmula:C52H72N12O11Pureza:97.70%Forma y color:SolidPeso molecular:1041.2LHC-165
CAS:LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.Fórmula:C29H32F2N3O7PPureza:98%Forma y color:SolidPeso molecular:603.55Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Fórmula:C33H40O19Pureza:98.78% - 99.13%Forma y color:SolidPeso molecular:740.66Polyinosinic-polycytidylic acid
CAS:Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic double-stranded RNA (dsRNA) analog and an immunostimulant that acts as the most potent IFN inducer.Fórmula:(C10H13N4O8P)x·(C9H14N3O8P)xPureza:90%Forma y color:SolidPeso molecular:671.4CL264
CAS:CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.Fórmula:C19H23N7O4Pureza:97.14%Forma y color:SolidPeso molecular:413.43Ref: TM-T10833
1mg51,00€5mg116,00€10mg192,00€25mg304,00€50mg420,00€100mg560,00€200mg755,00€1mL*10mM (DMSO)128,00€3M-011
CAS:3M-011: potent TLR7/8 agonist, cytokine inducer, enhances radiotherapy, fights H3N2, and has anti-tumor effects.Fórmula:C18H25N5O3SPureza:98%Forma y color:SolidPeso molecular:391.49IAXO-102
CAS:IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling.Fórmula:C35H71NO5Pureza:98.17%Forma y color:SolidPeso molecular:585.94Bropirimine
CAS:Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.Fórmula:C10H8BrN3OPureza:99.01%Forma y color:SolidPeso molecular:266.09TL8-506
CAS:TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammatory and autoimmune diseases.Fórmula:C20H17N3O2Pureza:95%Forma y color:SolidPeso molecular:331.37MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA
MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA is the trifluoroacetate form of MC-Val-Cit-PAB-Amide-TLR7 agonist 4,a HER2-TLR7 and HER2- TLR8 immune agonist complexes.Fórmula:C54H73F3N12O13Pureza:99.67%Forma y color:SolidPeso molecular:1155.22Ref: TM-T74468L
1mg201,00€5mg497,00€10mg701,00€25mg1.094,00€50mg1.508,00€100mg1.931,00€200mg2.637,00€BBIQ
CAS:BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of 59.1Fórmula:C21H22N4Pureza:98.02%Forma y color:SolidPeso molecular:330.43Motolimod
CAS:Motolimod (VTX-378) (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.Fórmula:C28H34N4O2Pureza:97.43% - 99.27%Forma y color:SolidPeso molecular:458.6TLR7 agonist 3
CAS:TLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and is used in the study of diseases of the immune system.Fórmula:C18H24N4OPureza:99.27%Forma y color:SolidPeso molecular:312.41Ref: TM-T38614
1mg115,00€5mg274,00€10mg455,00€25mg748,00€50mg1.064,00€100mg1.415,00€1mL*10mM (DMSO)303,00€VB 201
CAS:VB 201 is a small molecule of oxidized phospholipids with anti-inflammatory activity that can be used to study atherosclerosis.Fórmula:C29H60NO8PPureza:100%Forma y color:SolidPeso molecular:581.76E6446 dihydrochloride
CAS:E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM.Fórmula:C27H37Cl2N3O3Pureza:98.44%Forma y color:SolidPeso molecular:522.51Ref: TM-T4068
1mg107,00€2mg169,00€5mg304,00€10mg376,00€25mg628,00€50mg895,00€100mg1.216,00€200mg1.634,00€1V209
CAS:1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.Fórmula:C16H17N5O5Pureza:99.61%Forma y color:SolidPeso molecular:359.34Ref: TM-T8316
1mg38,00€5mg79,00€10mg126,00€25mg271,00€50mg395,00€100mg560,00€200mg797,00€1mL*10mM (DMSO)87,00€CU-CPT9b
CAS:CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).Fórmula:C16H13NO2Pureza:98.10%Forma y color:SolidPeso molecular:251.28Chloranil
CAS:Chloranil (tetrachloro-p-benzoquinone) induces inflammation and neurological dysfunction and can be used to model inflammation in mice.Fórmula:C6Cl4O2Pureza:99.38%Forma y color:SolidPeso molecular:245.88
