p38 MAPK
Las p38 MAPK son un subgrupo de MAPK que responden a señales de estrés y están involucradas en la regulación de la inflamación, la diferenciación celular, la apoptosis y la autofagia. La señalización de p38 MAPK es crucial en las respuestas inmunitarias y está implicada en varias enfermedades, incluidas las condiciones inflamatorias crónicas, el cáncer y los trastornos neurodegenerativos. En CymitQuimica, ofrecemos una gama completa de inhibidores y moduladores de p38 MAPK para apoyar su investigación en inflamación, respuesta al estrés y desarrollo terapéutico.
Productos de "p38 MAPK"
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AKP-001
CAS:AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.Fórmula:C21H13ClF2N4O2Pureza:99.50% - 99.92%Forma y color:SolidPeso molecular:426.8Cristacarpin
CAS:Cristacarpin targets DNA repair-deficient yeast, induces ER stress and ROS, triggers senescence in pancreatic/breast cancer by halting G1 cell cycle.Fórmula:C21H22O5Pureza:98%Forma y color:SolidPeso molecular:354.402Bakuchiol
CAS:Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.Fórmula:C18H24OPureza:98.69% - 99.47%Forma y color:Brownish Yellow Liquid ViscousPeso molecular:256.38Pamapimod
CAS:Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Fórmula:C19H20F2N4O4Pureza:97.63% - 99.99%Forma y color:SolidPeso molecular:406.38Ref: TM-T6927
1mg56,00€5mg119,00€10mg187,00€25mg378,00€50mg605,00€100mg852,00€500mg1.700,00€1mL*10mM (DMSO)131,00€AL 8697
CAS:AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.Fórmula:C21H21F3N4OPureza:98.96% - 99.26%Forma y color:SolidPeso molecular:402.41Ref: TM-T10277
1mg70,00€5mg145,00€10mg207,00€25mg348,00€50mg495,00€100mg678,00€500mgA consultar1mL*10mM (DMSO)169,00€CK1-IN-1
CAS:CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.Fórmula:C24H15F2N3Pureza:98.79%Forma y color:SolidPeso molecular:383.39Ref: TM-T5393
1mg49,00€2mg65,00€5mg97,00€10mg160,00€25mg305,00€50mg472,00€100mg707,00€1mL*10mM (DMSO)106,00€SB 242235
CAS:SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.Fórmula:C19H20FN5OPureza:99.13% - 99.68%Forma y color:SolidPeso molecular:353.39Ref: TM-T5S2358
1mg57,00€2mg81,00€5mg111,00€10mg160,00€25mg263,00€50mg378,00€100mg558,00€200mg797,00€1mL*10mM (DMSO)123,00€Dilmapimod
CAS:Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Fórmula:C23H19F3N4O3Pureza:97.53%Forma y color:SolidPeso molecular:456.42Neflamapimod
CAS:Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.Fórmula:C19H9Cl2F2N3OSPureza:99.02% - ≥95%Forma y color:SolidPeso molecular:436.26Sesamolin
CAS:Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.Fórmula:C20H18O7Pureza:98.77% - 99.04%Forma y color:SolidPeso molecular:370.35Ref: TM-T5S2283
1mg40,00€5mg85,00€10mg135,00€25mg216,00€50mg324,00€100mg472,00€500mg1.026,00€1mL*10mM (DMSO)88,00€MW-150
CAS:MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Fórmula:C24H23N5Pureza:97.35% - 99.27%Forma y color:SolidPeso molecular:381.47Ref: TM-T5494
1mg39,00€5mg96,00€10mg153,00€25mg305,00€50mg454,00€100mg655,00€500mg1.406,00€1mL*10mM (DMSO)114,00€SJFα
CAS:SJFα (SJF alpha) degrades p38α and p38δ and can be used in cancer research.Fórmula:C59H67F2N7O11SPureza:95.25%Forma y color:SolidPeso molecular:1120.27Dihydrocaffeic acid
CAS:Dihydrocaffeic acid, a chlorogenic acid metabolite, has antioxidant, anti-Alzheimer's, neuroprotective, and lipid-lowering properties.Fórmula:C9H10O4Pureza:98.63%Forma y color:SolidPeso molecular:182.17SB 203580 hydrochloride
CAS:SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.Fórmula:C21H17ClFN3OSPureza:97.79%Forma y color:SolidPeso molecular:413.9Iroxanadine
CAS:Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation inFórmula:C14H20N4OPureza:100% - 97.92%Forma y color:SolidPeso molecular:260.33Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Fórmula:C24H21F2NO4Pureza:100% - 99.76%Forma y color:SolidPeso molecular:425.42Ref: TM-T6130
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg208,00€50mg313,00€100mg465,00€1mL*10mM (DMSO)87,00€LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Fórmula:C25H25F3N4O4Pureza:98.3% - 99.92%Forma y color:SolidPeso molecular:502.49Ref: TM-T11898
1mg52,00€5mg122,00€10mg185,00€25mg363,00€50mg567,00€100mg690,00€200mg948,00€500mg1.444,00€1mL*10mM (DMSO)135,00€Lucidenic acid F
CAS:Lucidenic acid F as a modulator of JNK and p38, it shows potent inhibitory effects on EBV-EA induction.Fórmula:C27H36O6Pureza:98%Forma y color:SolidPeso molecular:456.57
