PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Productos de "PPAR"
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CP-868388 free base
CAS:CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.Fórmula:C26H33NO5Pureza:99.84%Forma y color:SolidPeso molecular:439.54BAY-0069
CAS:BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can beFórmula:C22H16BrN3O4Pureza:99.41%Forma y color:SoildPeso molecular:466.28Bezafibrate
CAS:Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES.Fórmula:C19H20ClNO4Pureza:99.56% - 99.82%Forma y color:SolidPeso molecular:361.82MA-0204
CAS:MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human,Fórmula:C25H27F3N2O4Pureza:97.80%Forma y color:SolidPeso molecular:476.49Ref: TM-T15945
1mg96,00€5mg178,00€10mg301,00€25mg490,00€50mg677,00€100mg900,00€200mg1.206,00€1mL*10mM (DMSO)187,00€DG172 dihydrochloride
CAS:DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).Fórmula:C20H22BrCl2N3Pureza:99.87%Forma y color:SolidPeso molecular:455.2Norathyriol
CAS:Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.Fórmula:C13H8O6Pureza:98.90% - 98.93%Forma y color:SolidPeso molecular:260.2Ref: TM-TN1990
1mg149,00€5mg354,00€10mg528,00€25mg852,00€50mg1.159,00€100mg1.568,00€1mL*10mM (DMSO)522,00€T0070907
CAS:T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.Fórmula:C12H8ClN3O3Pureza:99.36% - 99.95%Forma y color:SolidPeso molecular:277.66Ref: TM-T6689
5mg49,00€10mg58,00€25mg92,00€50mg147,00€100mg197,00€200mg255,00€500mg430,00€1mL*10mM (DMSO)55,00€MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Fórmula:C27H34ClNO2SPureza:98.9% - 99.78%Forma y color:SolidPeso molecular:472.08Ref: TM-T6893
1mg35,00€2mg48,00€5mg70,00€10mg111,00€25mg216,00€50mg354,00€100mg567,00€500mg1.198,00€1mL*10mM (DMSO)72,00€Mavodelpar free acid hydrochloride
Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.Fórmula:C31H31ClFNO5Pureza:99.39%Forma y color:SoildPeso molecular:552.03Arhalofenate
CAS:Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.Fórmula:C19H17ClF3NO4Pureza:98.97%Forma y color:SolidPeso molecular:415.79Ref: TM-T16022
1mg131,00€5mg286,00€10mg430,00€25mg710,00€50mg998,00€100mg1.349,00€500mg2.688,00€1mL*10mM (DMSO)330,00€Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Forma y color:SolidPeso molecular:393.89Sulotroban
CAS:sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.Fórmula:C16H17NO5SPureza:98.35% - 99.29%Forma y color:SolidPeso molecular:335.37DSO-5a
CAS:DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.Fórmula:C23H24N2O7Pureza:98%Forma y color:SolidPeso molecular:440.45Clofibrate
CAS:Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.Fórmula:C12H15ClO3Pureza:98.77%Forma y color:Oil LiquidPeso molecular:242.7ARH-049020
CAS:ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.Fórmula:C24H31NO6Pureza:99.67% - 99.82%Forma y color:SolidPeso molecular:429.51FTX-6746
CAS:FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.Fórmula:C16H7ClF2N2OPureza:98.68%Forma y color:SolidPeso molecular:316.69Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Fórmula:C20H18O11Pureza:97.02% - 99.94%Forma y color:White PowderPeso molecular:434.35Ref: TM-T6S0117
1mg58,00€5mg97,00€10mg160,00€25mg283,00€50mg418,00€100mg615,00€200mg878,00€1mL*10mM (DMSO)111,00€GSK376501A
CAS:GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.Fórmula:C32H37NO6Pureza:100%Forma y color:SolidPeso molecular:531.64NSC-87877
CAS:NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.Fórmula:C19H13N3O7S2Pureza:97.35%Forma y color:SolidPeso molecular:459.45PPAR α/PPARA Protein, Human, Recombinant (His)
PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:31.36 kDa (predicted)
