Fosfolipasa
Las fosfolipasas son un grupo de enzimas que hidrolizan fosfolípidos en ácidos grasos y otras sustancias lipofílicas, desempeñando un papel crítico en la biología de las membranas y la generación de moléculas de señalización. Los inhibidores de fosfolipasas se utilizan para estudiar su papel en enfermedades inflamatorias, trastornos cardiovasculares y neurodegeneración. Estos inhibidores también son valiosos para explorar las vías de señalización de lípidos y sus implicaciones en los mecanismos de enfermedades. En CymitQuimica, ofrecemos una variedad de inhibidores de fosfolipasas para apoyar su investigación en inflamación, metabolismo de lípidos y señalización celular.
Productos de "Fosfolipasa"
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trans-Benzylideneacetone
CAS:trans-Benzylideneacetone (Acetocinnamone) is used in various synthetic preparations.Fórmula:C10H10OPureza:97.48%Forma y color:Light Yellow Low Melting Crystalline MassPeso molecular:146.19Aristolochic acid C
CAS:Aristolochic acid C is a derivative of Aristolochic acid which is a phospholipase A2 inhibitor.Fórmula:C16H9NO7Pureza:98.14%Forma y color:White PowderPeso molecular:327.25Carbazochrome
CAS:Carbazochrome (Adchnon) is an antihemorrhagic that promotes platelet aggregation to stop bleeding, possibly for surgeries and hemorrhoids treatment.Fórmula:C10H12N4O3Pureza:98.36%Forma y color:Nacarat Crystalline PowderPeso molecular:236.23Fuzapladib
CAS:Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.Fórmula:C15H20F3N3O3SPureza:99.65%Forma y color:SoildPeso molecular:379.4Tris(2,4-di-tert-butylphenyl)phosphate
CAS:Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.Fórmula:C42H63O4PPureza:99.73%Forma y color:SolidPeso molecular:662.92ML299
CAS:ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 nM, respectively).Fórmula:C23H26BrFN4O2Pureza:98%Forma y color:SolidPeso molecular:489.38ML-211
CAS:ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)Fórmula:C25H30N4O2Pureza:97.07%Forma y color:SolidPeso molecular:418.53BAPTA
CAS:BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.Fórmula:C22H24N2O10Pureza:96.28% - ≥95%Forma y color:White SolidPeso molecular:476.43LCL521
CAS:LCL521 inhibits lysosomal acid sphingomyelinase (ASMase).LCL521 is an acid ceramidase (ACDase) inhibitor.Fórmula:C31H52N4O7Pureza:98%Forma y color:SolidPeso molecular:592.77ML348
CAS:ML348 (GNF-Pf-1127) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).Fórmula:C18H17ClF3N3O3Pureza:99% - 99.88%Forma y color:SolidPeso molecular:415.79Ref: TM-T3439
2mg47,00€5mg69,00€10mg97,00€25mg227,00€50mg354,00€100mg567,00€200mg792,00€500mg1.198,00€AACOCF3
CAS:AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.Fórmula:C21H31F3OPureza:99% - 99%Forma y color:Yellow LiquidPeso molecular:356.473-Nitrocoumarin
CAS:3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) is a potent and selective Phospholipase C-γ (PLCγ) inhibitor.Fórmula:C9H5NO4Pureza:97.28%Forma y color:SolidPeso molecular:191.14U-73343
CAS:U-73343 is an inactive analog of U-73122 and can be used as a negative control. U-73122 dose-dependently inhibits acid secretion irrespective of the stimulant.Fórmula:C29H42N2O3Pureza:99.06%Forma y color:SolidPeso molecular:466.66GK187
CAS:GK187 is a selective and potent Group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor, used in the study of neurological disorders.Fórmula:C14H15F5O2Forma y color:SolidPeso molecular:310.26Ref: TM-T37221
1mg87,00€5mg183,00€10mg296,00€25mg565,00€50mg909,00€100mg1.444,00€200mg1.882,00€1mL*10mM (DMSO)202,00€Lp-PLA2-IN-16
CAS:Lp-PLA2-IN-16 (Example 1) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential applications in Alzheimer's disease research [1].Fórmula:C22H17F5N4O3Pureza:98%Forma y color:SolidPeso molecular:480.39Columbin
CAS:Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.Fórmula:C20H22O6Pureza:99.34% - 99.74%Forma y color:SolidPeso molecular:358.39Lp-PLA2-IN-12
CAS:Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease (AD), glaucoma, age-Fórmula:C24H23F2N5O3Pureza:98%Forma y color:SolidPeso molecular:467.47Rhamnetin
CAS:Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities.Fórmula:C16H12O7Pureza:97.6%Forma y color:SolidPeso molecular:316.26Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Fórmula:C17H19N3O3SPureza:98.43% - 98.48%Forma y color:White SolidPeso molecular:345.42LEI110
CAS:LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.Fórmula:C25H23F3N2O3Pureza:97.56% - 98.8%Forma y color:SolidPeso molecular:456.46
