Fosfolipasa
Las fosfolipasas son un grupo de enzimas que hidrolizan fosfolípidos en ácidos grasos y otras sustancias lipofílicas, desempeñando un papel crítico en la biología de las membranas y la generación de moléculas de señalización. Los inhibidores de fosfolipasas se utilizan para estudiar su papel en enfermedades inflamatorias, trastornos cardiovasculares y neurodegeneración. Estos inhibidores también son valiosos para explorar las vías de señalización de lípidos y sus implicaciones en los mecanismos de enfermedades. En CymitQuimica, ofrecemos una variedad de inhibidores de fosfolipasas para apoyar su investigación en inflamación, metabolismo de lípidos y señalización celular.
Productos de "Fosfolipasa"
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GW4869
CAS:GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM).Fórmula:C30H30Cl2N6O2Pureza:98.47% - 99.66%Forma y color:SolidPeso molecular:577.51-Myristoyl-2-Linoleoyl-sn-glycero-3-PC
CAS:1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.Fórmula:C40H76NO8PForma y color:SolidPeso molecular:730.01VU0155069
CAS:VU0155069, a selective PLD1 inhibitor (IC50: 46 nM), halts cancer cell migration in transwell assays.Fórmula:C26H27ClN4O2Pureza:98.32%Forma y color:SolidPeso molecular:462.97N-(p-amylcinnamoyl) Anthranilic Acid
CAS:N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker.Fórmula:C21H23NO3Pureza:99.35% - 99.67%Forma y color:SolidPeso molecular:337.41Lp-PLA2-IN-3
CAS:Lp-PLA2-IN-3: Potent oral inhibitor of human Lp-PLA2 with a 14 nM IC50.Fórmula:C20H13ClF3N3O3SPureza:99.49%Forma y color:SolidPeso molecular:467.85Ref: TM-T11874
1mg96,00€2mg139,00€5mg227,00€10mg359,00€25mg595,00€50mg842,00€100mg1.121,00€500mg2.262,00€1mL*10mM (DMSO)233,00€nSMase2-IN-1
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.Fórmula:C12H17N5OPureza:98%Forma y color:SolidPeso molecular:247.3U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Fórmula:C29H40N2O3Pureza:97.50%Forma y color:Solid Off-WhitePeso molecular:464.64ML-298
CAS:ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM).Fórmula:C22H23F3N4O2Pureza:99.35%Forma y color:SolidPeso molecular:432.44FIPI
CAS:FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.Fórmula:C23H24FN5O2Pureza:98.01% - 99.08%Forma y color:SolidPeso molecular:421.47Atg4B-IN-2
CAS:Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists the anticancer activity of resistant prostate cancer drugs.Fórmula:C21H30O3Pureza:98.86%Forma y color:SolidPeso molecular:330.46Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Fórmula:C17H18N3NaO3SPureza:99.57%Forma y color:Clear In WaterPeso molecular:367.4Lp-PLA2-IN-15
CAS:Lp-PLA2-IN-15 (example 2) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential application in Alzheimer's disease research [1].Fórmula:C22H17F5N4O3Pureza:98%Forma y color:SolidPeso molecular:480.39Lp-PLA2-IN-1
CAS:Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.Fórmula:C21H17F5N4O3Pureza:99.25%Forma y color:SolidPeso molecular:468.38Neomycin sulfate
CAS:Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exertFórmula:C23H46N6O13·3H2SO4Pureza:98.79% - 99.87%Forma y color:Tan PowderPeso molecular:908.87Lp-PLA2-IN-13
CAS:Lp-PLA2-IN-13 (compound 15), a potent Lp-PLA2 inhibitor, holds potential for research in neurodegenerative-related diseases [1].Fórmula:C22H17F5N4O4Pureza:98%Forma y color:SolidPeso molecular:496.39DPTIP hydrochloride
CAS:DPTIP hydrochloride is a potent inhibitor of neutral sphingomyelinase (N-SMase 2) that can cross the blood-brain barrier. It acts as an exosome inhibitor with an IC50 value of 30 nM.Fórmula:C21H19ClN2O3SForma y color:SolidPeso molecular:414.91Halopemide
CAS:Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2).Fórmula:C21H22ClFN4O2Pureza:96.29%Forma y color:SolidPeso molecular:416.88Niflumic acid
CAS:Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.Fórmula:C13H9F3N2O2Pureza:99.47%Forma y color:SolidPeso molecular:282.22BIRM 271
CAS:BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.Fórmula:C21H25N3OPureza:99.38%Forma y color:SoildPeso molecular:335.44VU0155056
CAS:VU0155056 is a dual PLD1/2 inhibitor with IC50 < 1 µM in cellular assays, inhibits breast cancer cell invasion.Fórmula:C25H26N4O2Pureza:98.6%Forma y color:SolidPeso molecular:414.5
