AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Productos de "AChR"
Ordenar por
Terodiline hydrochloride
CAS:Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),Fórmula:C20H28ClNPureza:98%Forma y color:SolidPeso molecular:317.9Nitenpyram
CAS:Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.Fórmula:C11H15ClN4O2Pureza:98.42%Forma y color:Light-Yellow CrystalPeso molecular:270.72nAChR agonist 1
CAS:nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.Fórmula:C20H18ClNO3S2Pureza:97.59%Forma y color:SolidPeso molecular:419.94Ref: TM-T12165
1mg94,00€5mg170,00€10mg259,00€25mg424,00€50mg562,00€100mg775,00€200mg1.026,00€1mL*10mM (DMSO)192,00€Pancuronium dibromide
CAS:Pancuronium dibromide (Pavulon), a competitive AChR antagonist, acts as a skeletal muscle relaxant. Pancuronium dibromide blocks neuromuscular transmission.Fórmula:C35H60Br2N2O4Pureza:99.86%Forma y color:solidPeso molecular:732.67Ref: TM-T0166
5mg38,00€10mg55,00€25mg82,00€50mg115,00€100mg188,00€200mg235,00€500mg394,00€1mL*10mM (DMSO)63,00€Darifenacin hydrobromide
CAS:Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Fórmula:C28H31BrN2O2Pureza:100% - 99.75%Forma y color:SolidPeso molecular:505.45VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.Fórmula:C18H20N6O3S2Pureza:96.53% - 98.26%Forma y color:SolidPeso molecular:432.52Adiphenine hydrochloride
CAS:Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.Fórmula:C20H25NO2·HClPureza:97.76% - 99.13%Forma y color:White Or Almost White PowderPeso molecular:347.88Methacholine Chloride
CAS:Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of acetylcholine.Fórmula:C8H18ClNO2Pureza:99.37% - 99.74%Forma y color:White Hygroscopic Crystals With Slight Odor Of Dead FishPeso molecular:195.69Ispronicline
CAS:Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitiveFórmula:C14H22N2OPureza:96.49% - 99.16%Forma y color:SolidPeso molecular:234.348-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Fórmula:C5H6N6Pureza:98.34%Forma y color:SolidPeso molecular:150.14PNU-120596
CAS:PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.Fórmula:C13H14ClN3O4Pureza:98.34%Forma y color:SolidPeso molecular:311.72suvn-911
CAS:suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.Fórmula:C11H14Cl2N2OPureza:98.88%Forma y color:SolidPeso molecular:261.15Ref: TM-T9787
1mg71,00€5mg140,00€10mg215,00€25mg359,00€50mg510,00€100mg695,00€200mg937,00€1mL*10mM (DMSO)182,00€MHP 133
CAS:MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).Fórmula:C17H20ClN5O3Pureza:98%Forma y color:SolidPeso molecular:377.83Ipratropium Bromide
CAS:Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.Fórmula:C20H30BrNO3Pureza:99.91%Forma y color:SolidPeso molecular:412.37Varenicline Tartrate
CAS:Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.Fórmula:C13H13N3·C4H6O6Pureza:98.23% - 98.32%Forma y color:Tan SolidPeso molecular:361.35GSK233705
CAS:GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.Fórmula:C24H29BrN2Pureza:99.67% - 99.76%Forma y color:SolidPeso molecular:425.4DMAB-anabaseine dihydrochloride
CAS:DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containingFórmula:C19H23Cl2N3Pureza:99.86%Forma y color:SolidPeso molecular:364.31A-867744
CAS:A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).Fórmula:C20H19ClN2O3SPureza:95.66%Forma y color:SolidPeso molecular:402.89MK-7622
CAS:MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.Fórmula:C25H25N3O2Pureza:99.77% - 99.8%Forma y color:SolidPeso molecular:399.48JHU37152
CAS:JHU37152 is a DREADD agonist; Ki: 1.8 nM at hM3Dq, 8.7 nM at hM4Di; EC50: 5 nM (hM3Dq), 0.5 nM (hM4Di) in HEK-293 cell assays.Fórmula:C19H20ClFN4Pureza:99.72%Forma y color:SolidPeso molecular:358.84Ref: TM-T9019
2mg35,00€5mg52,00€10mg90,00€25mg170,00€50mg255,00€100mg375,00€200mg533,00€1mL*10mM (DMSO)58,00€
