AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Productos de "AChR"
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Oxotremorine M iodide
CAS:Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.Fórmula:C11H19IN2OPureza:98.75%Forma y color:SolidPeso molecular:322.19LY2119620
CAS:LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.Fórmula:C19H24ClN5O3SPureza:99.7%Forma y color:SolidPeso molecular:437.94UP202-56
CAS:UP202-56 is an adenosinergic agonist and is an adenosine analog.Fórmula:C33H37N7O4Pureza:98%Forma y color:SolidPeso molecular:595.69NBTGR
CAS:NBTGR is a potent nucleoside transport inhibitor(adenosine uptake ,Ki of 70 nM).Fórmula:C17H18N6O6SPureza:98%Forma y color:SolidPeso molecular:434.43mAChr-in-1
CAS:mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).Fórmula:C23H25IN2O2Pureza:98%Forma y color:SolidPeso molecular:488.36VU0467154
CAS:VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.Fórmula:C17H15F3N4O3S2Pureza:98.05% - 98.28%Forma y color:SolidPeso molecular:444.45Ref: TM-T17244
1mg52,00€5mg97,00€10mg139,00€25mg263,00€50mg444,00€100mg772,00€200mg1.026,00€1mL*10mM (DMSO)111,00€CHF5407
CAS:CHF5407(SVT-47060) is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect onFórmula:C27H25BrF4N2O3SPureza:100%Forma y color:SolidPeso molecular:613.46V-11-0711 HCl
V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.Fórmula:C27H36ClNO3Pureza:100%Forma y color:SolidPeso molecular:458.03Varenicline
CAS:Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.Fórmula:C13H13N3Pureza:99.76%Forma y color:SolidPeso molecular:211.26Ref: TM-T4246L
2mg35,00€5mg52,00€10mg80,00€25mg144,00€50mg210,00€100mg329,00€200mg490,00€1mL*10mM (DMSO)58,00€CCMI
CAS:CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.Fórmula:C19H15Cl2N3O2Pureza:100%Forma y color:SolidPeso molecular:388.25M4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Fórmula:C14H18N4OSPureza:98.25%Forma y color:SolidPeso molecular:290.38SIB-1553A hydrochloride
CAS:SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligandFórmula:C13H20ClNOSPureza:99.47% - 99.71%Forma y color:SolidPeso molecular:273.82Tacrine hydrochloride (hydrate)
CAS:Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier.Fórmula:C13H14N2·XHCl·XH2OPureza:99.01% - 99.89%Forma y color:SolidPeso molecular:234.72PNU-282987
CAS:PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).Fórmula:C14H18Cl2N2OPureza:100% - 99.92%Forma y color:SolidPeso molecular:301.21PF-03635659
CAS:PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.Fórmula:C28H32N2O3Pureza:98.05% - 99.83%Forma y color:SolidPeso molecular:444.57Xanomeline oxalate
CAS:Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.Fórmula:C16H25N3O5SPureza:98.22%Forma y color:SolidPeso molecular:371.45Ref: TM-T13353
5mg38,00€10mg58,00€25mg105,00€50mg168,00€100mg259,00€200mg373,00€1mL*10mM (DMSO)42,00€SEN12333
CAS:SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonistFórmula:C20H25N3O2Pureza:99.02%Forma y color:SolidPeso molecular:339.43Ref: TM-T23348
2mg39,00€5mg57,00€10mg95,00€25mg167,00€50mg269,00€100mg432,00€200mg622,00€1mL*10mM (DMSO)63,00€AChE/BChE-IN-10
CAS:AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.Fórmula:C26H30N2O2Pureza:99.55% - 99.75%Forma y color:SoildPeso molecular:402.53Ref: TM-T61969
5mg44,00€10mg67,00€25mg126,00€50mg188,00€100mg306,00€200mg454,00€1mL*10mM (DMSO)54,00€N-0861 racemate
CAS:N-0861 racemate is the racemate of N-0861.Fórmula:C13H17N5Pureza:98%Forma y color:SolidPeso molecular:243.31Trospium chloride
CAS:Trospium chloride treats urinary incontinence without causing liver damage.Fórmula:C25H30ClNO3Pureza:100% - 99.92%Forma y color:White To Off-White PowderPeso molecular:427.964
