Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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TAT-SAMβA
TAT-SAMβA, an RNAENFDRF (SAMβA) peptide conjugated to the TAT 47-57 protein-derived cell-penetrating peptide, acts as a selective antagonist of the Mfn1-βIIPKCFórmula:C118H195N51O31Pureza:98%Forma y color:SolidPeso molecular:2824.13Hexapeptide-10 Acetate
Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.Fórmula:C30H57N7O10Pureza:98.84%Forma y color:SolidPeso molecular:675.81Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Fórmula:C22H15NO4S2Pureza:98% - 98.49%Forma y color:SolidPeso molecular:421.49PI3K-IN-48
PI3K-IN-48, a PI3K inhibitor, exhibits an IC50 of 1.55 ± 0.18 μM in A549 cells, demonstrating its potency in this context.Fórmula:C25H21FN2O4Pureza:98%Forma y color:SolidPeso molecular:432.44BAY1125976
CAS:BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)Fórmula:C23H21N5OPureza:98.87% - ≥98%Forma y color:SolidPeso molecular:383.45Ref: TM-T7315
1mg39,00€2mg51,00€5mg88,00€10mg137,00€25mg249,00€50mg439,00€100mg647,00€500mg1.359,00€1mL*10mM (DMSO)87,00€Paeoniflorin
CAS:Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.Fórmula:C23H28O11Pureza:96.9% - 97.16%Forma y color:White Fine PowderPeso molecular:480.46CpCDPK1/TgCDPK1-IN-1
CAS:CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.Fórmula:C18H17N5Pureza:98.71%Forma y color:SolidPeso molecular:303.36Cevipabulin
CAS:Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cellFórmula:C18H18ClF5N6OPureza:99.53%Forma y color:SolidPeso molecular:464.82S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Fórmula:C22H21NO2SPureza:97.02%Forma y color:Almost White To Light Yellow Granular PowderPeso molecular:363.47Litronesib
CAS:Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.Fórmula:C23H37N5O4S2Pureza:98%Forma y color:SolidPeso molecular:511.7Plinabulin
CAS:Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).Fórmula:C19H20N4O2Pureza:100% - 98.69%Forma y color:SolidPeso molecular:336.39Staurosporine
CAS:Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFórmula:C28H26N4O3Pureza:99.24% - 99.98%Forma y color:Off-White PowderPeso molecular:466.53Ref: TM-T6680
1mg62,00€2mg87,00€5mg97,00€10mg145,00€25mg246,00€50mg401,00€100mg597,00€500mg1.283,00€1mL*10mM (DMSO)109,00€Carbenoxolone disodium
CAS:Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.Fórmula:C34H48Na2O7Pureza:98.01%Forma y color:SolidPeso molecular:614.72Tubulin inhibitor 1
CAS:Tubulin inhibitor 1 blocks tubulin polymerization, with strong anti-tumor effects, induces apoptosis and G2/M mitotic arrest.Fórmula:C21H24N2O4Pureza:98%Forma y color:SolidPeso molecular:368.43Eribulin
CAS:Eribulin binds microtubules, halts cancer cell growth, treating metastatic breast cancer.Fórmula:C40H59NO11Pureza:99.96%Forma y color:SolidPeso molecular:729.90Hypocrellin A
CAS:Hypocrellin A is a natural PKC inhibitor with light-induced antitumor, antifungal and antiviral activities.Cost-effective and quality-assured.Fórmula:C30H26O10Pureza:98% - 99.81%Forma y color:SolidPeso molecular:546.52Conteltinib
CAS:Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.Fórmula:C32H45N9O3SPureza:98.12% - 99.54%Forma y color:SolidPeso molecular:635.82Ref: TM-T14997
1mg77,00€5mg167,00€10mg240,00€25mg409,00€50mg572,00€100mg800,00€1mL*10mM (DMSO)227,00€Hsp110-STAT3 interaction-IN-2
Hsp110-STAT3 interaction-IN-2 (compound 10b) is an inhibitor of the Hsp110-STAT3 interaction. It is utilized in research related to pulmonary arterial hypertension (PAH).Fórmula:C24H18F3N5O3Forma y color:SolidPeso molecular:481.43AKT-IN-25
CAS:AKT-IN-25 (Compound 14a) is an inhibitor of Akt that prevents the phosphorylation of Akt, thereby hindering the PI3K/Akt/mTOR signaling pathway. It arrests the cell cycle at the G1 phase, inhibits the migration of PANC-1 cells, and suppresses the proliferation of cancer cells PANC-1, PATU-T, and SUIT-2, with IC50 values of 3.05, 1.32, and 3.85 μM, respectively.Fórmula:C14H16N4OForma y color:SolidPeso molecular:256.3Tasidotin hydrochloride
CAS:Tasidotin hydrochloride, a dolastatin 15 analog, inhibits microtubule assembly and dynamics.Fórmula:C32H59ClN6O5Pureza:98%Forma y color:SolidPeso molecular:643.30
