Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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FRAX486
CAS:FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.Fórmula:C25H23Cl2FN6OPureza:98.81%Forma y color:SolidPeso molecular:513.39AKT-IN-26
CAS:AKT-IN-26 (Compound 453) is an AKT inhibitor that binds to the Pleckstrin Homology (PH) domain of AKT. It is useful for research related to cell proliferation and cancer involving the AKT pathway.Fórmula:C21H17N5O4SForma y color:SolidPeso molecular:435.456JG-231
CAS:JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.Fórmula:C22H18BrCl2N3OS4Pureza:99.21%Forma y color:SolidPeso molecular:619.47TN-16
CAS:TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)Fórmula:C19H18N2O2Pureza:99.54%Forma y color:SolidPeso molecular:306.36LXW7
CAS:LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Fórmula:C29H48N12O12S2Pureza:100%Forma y color:SolidPeso molecular:820.89Batatasin III
CAS:Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancerFórmula:C15H16O3Pureza:99.16%Forma y color:SolidPeso molecular:244.29HM03
CAS:HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.Fórmula:C26H27ClN4O2Pureza:97.15%Forma y color:SolidPeso molecular:462.97AT7867
CAS:AT7867 inhibits Akt1/2/3 & p70S6K/PKA (IC50: 32/17/47 nM & 85/20 nM), minimal effect beyond AGC kinases.Fórmula:C20H20ClN3Pureza:99.63%Forma y color:SolidPeso molecular:337.85Ref: TM-T6304
2mg44,00€5mg65,00€10mg86,00€25mg135,00€50mg210,00€100mg313,00€200mg452,00€1mL*10mM (DMSO)65,00€2-Methylbutyrylcarnitine chloride
2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.Fórmula:C12H24ClNO4Forma y color:SolidPeso molecular:281.78Arginine-glycine-aspartic acid
CAS:RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Fórmula:C12H22N6O6Pureza:99.11%Forma y color:SolidPeso molecular:346.34Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Fórmula:C30H33Cl4N3O4Pureza:98%Forma y color:SolidPeso molecular:641.41Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFórmula:C18H16O8Pureza:99.50% - 99.85%Forma y color:SolidPeso molecular:360.31Afuresertib hydrochloride
CAS:Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)Fórmula:C18H18Cl3FN4OSPureza:99.96%Forma y color:SolidPeso molecular:463.8Ref: TM-T7885
2mg52,00€5mg74,00€10mg95,00€25mg163,00€50mg253,00€100mg437,00€200mg568,00€1mL*10mM (DMSO)86,00€Bersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:144.22 kDaDolastatin 10
CAS:Dolastatin 10 (DLS 10) is a powerful peptide with antimitotic properties, effectively inhibiting tubulin polymerization.Fórmula:C42H68N6O6SPureza:99.55%Forma y color:SolidPeso molecular:785.09Shepherdin 79-87 acetate
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.Fórmula:C43H68N12O14SPureza:98.08%Forma y color:SolidPeso molecular:1009.14G-5555
CAS:G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).Fórmula:C25H25ClN6O3Pureza:99.76% - 99.87%Forma y color:SolidPeso molecular:492.96Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Fórmula:C29H29F3N8OPureza:99.52% - 99.95%Forma y color:SolidPeso molecular:562.59Ref: TM-T4320
1mg35,00€5mg66,00€10mg87,00€25mg127,00€50mg163,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)87,00€Betamethasone 17-benzoate
CAS:Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).Fórmula:C29H33FO6Pureza:98%Forma y color:SolidPeso molecular:496.57EC 144
CAS:EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.Fórmula:C21H24ClN5O2Forma y color:SolidPeso molecular:413.9
