NF-κB
Le facteur nucléaire kappa B (NF-κB) est un facteur de transcription qui régule l'expression des gènes impliqués dans les réponses immunitaires, l'inflammation, la survie cellulaire et la prolifération. Le NF-κB est activé en réponse à divers stimuli, y compris les cytokines, les agents pathogènes et les signaux de stress. La dérégulation de la signalisation du NF-κB est associée à des maladies inflammatoires chroniques, au cancer et aux troubles auto-immuns. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de la voie NF-κB pour soutenir vos recherches en inflammation, oncologie et régulation immunitaire.
Produits appartenant à la catégorie "NF-κB"
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PROTAC IRAK4 ligand-4
CAS :PROTAC IRAK4 ligand-4, a Ligand for Target Protein for PROTAC (Ligand for Target Protein for PROTAC), exhibits anti-tumor activity and is utilized in synthesizing PROTAC IRAK4 degrader-12. This compound serves as a targeted ligand with specific applications in the development of cancer therapeutics.Formule :C24H26F2N6O3Couleur et forme :SolidMasse moléculaire :484.5INF 195
CAS :INF 195 is an inflammasome NLRP3 inhibitor that can be used to study myocardial ischemia and myocardial infarction.Formule :C17H22ClNO3Degré de pureté :99.78%Couleur et forme :SoildMasse moléculaire :323.81Stachydrine Hydrochloride
CAS :Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.Formule :C7H14ClNO2Degré de pureté :99.53% - 99.71%Couleur et forme :Light Yellow PasteMasse moléculaire :179.64Vanillic Acid
CAS :Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.Formule :C8H8O4Degré de pureté :99.82%Couleur et forme :White Odourless Crystals Or PowderMasse moléculaire :168.15Indacaterol maleate
CAS :Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.Formule :C28H32N2O7Degré de pureté :99.03% - 99.67%Couleur et forme :SolidMasse moléculaire :508.56Anti-inflammatory agent 51
CAS :Anti-inflammatory agent 51 amide/sulfonamide anti-inflammatory and anti-tumor activity inhibition of NF-κB activation acute lung injury and ulcerative colitis.Formule :C22H22N6O6SDegré de pureté :99.46%Couleur et forme :SoildMasse moléculaire :498.512-Hydroxychalcone
CAS :2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Formule :C15H12O2Degré de pureté :99.60%Couleur et forme :SolidMasse moléculaire :224.25Maslinic acid
CAS :Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.Formule :C30H48O4Degré de pureté :98.1% - 99.98%Couleur et forme :SolidMasse moléculaire :472.7Guaiacol
CAS :Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.Formule :C7H8O2Degré de pureté :99.83%Couleur et forme :Colourless To Pale Yellow Solid CrystallineMasse moléculaire :124.14ZB-R-55
CAS :ZB-R-55 is an oral and highly potent bimodal RIPK1 inhibitor with excellent kinase selectivity in lps-induced sepsis models for the study of SIRS and sepsis.Formule :C25H23N5O3Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :441.48Sinomenine
CAS :Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.Formule :C19H23NO4Degré de pureté :99.02% - 99.89%Couleur et forme :White PowderMasse moléculaire :329.39Karacoline
CAS :Karacolinem: natural compound, inhibits ECM breakdown in IDD through NF-κB pathway.Formule :C22H35NO4Degré de pureté :99.64% - 99.75%Couleur et forme :SolidMasse moléculaire :377.52Urolithin B
CAS :Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFormule :C13H8O3Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :212.2Selnoflast
CAS :Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of coronary arteries and ulcerative colitis.Formule :C20H29N3O3SDegré de pureté :100% - 99.82%Couleur et forme :SolidMasse moléculaire :391.53Neferine
CAS :Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formule :C38H44N2O6Degré de pureté :98.81% - 99.18%Couleur et forme :SolidMasse moléculaire :624.77anemarsaponin B
CAS :Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activityFormule :C45H74O18Degré de pureté :99.06% - 99.81%Couleur et forme :SolidMasse moléculaire :903.06(S)-(+)-Ibuprofen
CAS :(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).Formule :C13H18O2Degré de pureté :99.51% - 99.86%Couleur et forme :Colourless Crystalline SolidMasse moléculaire :206.28GSK2982772
CAS :GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.Formule :C20H19N5O3Degré de pureté :99.27% - 99.31%Couleur et forme :SolidMasse moléculaire :377.4Bay 65-1942 free base
CAS :Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.Formule :C22H25N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.45HOMOPLANTAGININ
CAS :Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and showsFormule :C22H22O11Degré de pureté :97.63% - 99.66%Couleur et forme :SolidMasse moléculaire :462.4Ref: TM-T4S0217
5mg50,00€10mg74,00€25mg140,00€50mg226,00€100mg324,00€200mg464,00€1mL*10mM (DMSO)52,00€
