NF-κB
Le facteur nucléaire kappa B (NF-κB) est un facteur de transcription qui régule l'expression des gènes impliqués dans les réponses immunitaires, l'inflammation, la survie cellulaire et la prolifération. Le NF-κB est activé en réponse à divers stimuli, y compris les cytokines, les agents pathogènes et les signaux de stress. La dérégulation de la signalisation du NF-κB est associée à des maladies inflammatoires chroniques, au cancer et aux troubles auto-immuns. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de la voie NF-κB pour soutenir vos recherches en inflammation, oncologie et régulation immunitaire.
Produits appartenant à la catégorie "NF-κB"
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NP3-146
CAS :NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.Formule :C20H27ClN2O5SDegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :442.96RIPK2-IN-5
CAS :RIPK2-IN-5 is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with potential anti-inflammatory activity for the study of diseases caused by immune dysfunctions.Formule :C21H14N4SDegré de pureté :98.85%Couleur et forme :SoildMasse moléculaire :354.43Sappanone A
CAS :Sappanone A is a high isoflavanone with anti-inflammatory properties.Sappanone A reduces allergic airway inflammation in ovalbumin-induced asthma.Formule :C16H12O5Degré de pureté :97.48% - 99.18%Couleur et forme :SolidMasse moléculaire :284.26Pinocembrin
CAS :Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Formule :C15H12O4Degré de pureté :100% - 99.61%Couleur et forme :SolidMasse moléculaire :256.25NF-κB/MAPK-IN-1
CAS :NF-κB/MAPK-IN-1 is an NF-κB and MAPK pathway inhibitor. NF-κB/MAPK-IN-1 is used to prevent rheumatoid arthritis (RA).Formule :C27H27NO7Degré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :477.51Ref: TM-T63119
1mg47,00€2mg60,00€5mg87,00€10mg154,00€25mg329,00€50mg492,00€100mg710,00€1mL*10mM (DMSO)93,00€CBL0137 hydrochloride
CAS :CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.Formule :C21H25ClN2O2Degré de pureté :98.59% - 99.35%Couleur et forme :SolidMasse moléculaire :372.88Nimbolide
CAS :Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.Formule :C27H30O7Degré de pureté :95.84% - 99.4%Couleur et forme :SolidMasse moléculaire :466.52Ref: TM-T16324
1mg88,00€5mg216,00€10mg376,00€25mg810,00€50mg1.074,00€100mg1.454,00€200mg1.882,00€1mL*10mM (DMSO)235,00€IRAK-1-4 Inhibitor I
CAS :IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.Formule :C20H21N5O4Degré de pureté :100% - 99.89%Couleur et forme :SolidMasse moléculaire :395.41Ref: TM-T2457
1mg44,00€5mg79,00€10mg110,00€25mg224,00€50mg376,00€100mg540,00€500mg1.130,00€1mL*10mM (DMSO)79,00€Stipuleanoside R2
CAS :Stipuleanoside R2 is a triterpenoid saponin that inhibits NF-κB activation and has potential applications in inflammation, immunology, and cancer research.Formule :C53H84O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1089.22Esculentoside H
CAS :Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.Formule :C48H76O21Degré de pureté :98.04% - 99.3%Couleur et forme :SolidMasse moléculaire :989.1Sootepin D
CAS :Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced NF-κB inhibitor(IC50 of 8.3μM),with anti-inflammatory activity.Formule :C31H48O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.71IMD-0560
CAS :IMD-0560 is a novel inhibitor of IκB kinase β.Formule :C15H8BrF6NO2Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :428.12Sulindac
CAS :Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Formule :C20H17FO3SDegré de pureté :99.09% - 99.15%Couleur et forme :Yellow SolidMasse moléculaire :356.41Goshonoside F5
CAS :Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.Formule :C32H54O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.771CID-2858522
CAS :CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).Formule :C28H39N3O3Degré de pureté :96.11%Couleur et forme :SolidMasse moléculaire :465.63Kuromanin chloride
CAS :Kuromanin chloride (Chrysontemin chloride) is potent antioxidants and free radical scavengers, may act as modulators of gene regulation and signal transductionFormule :C21H21ClO11Degré de pureté :97.27% - 98.69%Couleur et forme :SolidMasse moléculaire :484.84Ref: TM-T3406
1mg35,00€2mg50,00€5mg82,00€10mg110,00€25mg207,00€50mg306,00€100mg459,00€1mL*10mM (DMSO)88,00€IRAK4-IN-27
IRAK4-IN-27 (Compound 22) is a potent and selective IRAK4 inhibitor, demonstrating an IC50 of 8.7 nM.Formule :C23H22N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.46Cantleyoside
CAS :Cantleyoside, a natural cyclic enol ether terpene glycoside from Pterocephalus hookeri, can activate of the AMPK/Sirt1/NF-κB signaling pathway.Formule :C33H46O19Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :746.71TNFα activity modulator 3
CAS :TNFα Activity Modulator 3 (example 6) is a molecule that regulates TNF activity by inhibiting TNFα-induced NF-κB activation, making it applicable for related research.Formule :C27H24F2N6O2Couleur et forme :SolidMasse moléculaire :502.52BAL-0028
CAS :BAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for cancer research.Formule :C24H22FN3O2Degré de pureté :99.16%Couleur et forme :SoildMasse moléculaire :403.45
