c-Kit
Les inhibiteurs de c-Kit sont des composés qui bloquent l'activité du Récepteur du Facteur de Cellules Souches (c-Kit), une tyrosine kinase jouant un rôle crucial dans la survie, la prolifération et la différenciation cellulaires, en particulier dans les cellules hématopoïétiques. Les mutations de c-Kit sont liées à divers cancers, notamment les tumeurs stromales gastro-intestinales (GIST) et la leucémie. Chez CymitQuimica, nous proposons des inhibiteurs de c-Kit pour soutenir vos recherches en oncologie, hématologie et biologie des cellules souches.
Produits appartenant à la catégorie "c-Kit"
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Linifanib
CAS :Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormule :C21H18FN5ODegré de pureté :98% - 98.24%Couleur et forme :SolidMasse moléculaire :375.4Ref: TM-T2514
5mg50,00€10mg85,00€25mg126,00€50mg188,00€100mg274,00€200mg505,00€500mg815,00€1mL*10mM (DMSO)52,00€Anti-C-Kit Antibody (7P530)
Anti-C-Kit Antibody (7P530) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (7P530) can be used in FCM.Couleur et forme :Odour Liquidc-Kit-IN-1
CAS :c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).Formule :C26H21F2N5O3Degré de pureté :98.16% - 98.72%Couleur et forme :SolidMasse moléculaire :489.47Ref: TM-T4332
1mg46,00€2mg59,00€5mg87,00€10mg144,00€25mg304,00€50mg542,00€100mg778,00€500mg1.605,00€1mL*10mM (DMSO)94,00€Protein kinase inhibitor 10
CAS :Protein kinase inhibitor 10 is a protein kinase inhibitor with IC50 values of 28.9 μM, 13.6 μM, and 2.41 μM for TAM receptors, FAK, and KIT, respectively. It can inhibit abnormal and excessive cell proliferation, showing potential for research in the field of cancer treatment.Formule :C14H9FN6S2Couleur et forme :SolidMasse moléculaire :344.39Toceranib Phosphate
CAS :Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formule :C22H28FN4O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :494.45c-Kit-IN-8
CAS :C-Kit-IN-8 (Compound 53) acts as an inhibitor of c-Kit kinase, hampering uKIT kinase activity with an IC50 greater than 1 μM. Additionally, it inhibits the proliferation of both wild-type and mutant GIST430 and BaF3 cancer cells, exhibiting an IC50 greater than 0.1 μM.Formule :C24H26FN5O4Couleur et forme :SolidMasse moléculaire :467.49Masitinib mesylate
CAS :Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Formule :C29H34N6O4S2Degré de pureté :100% - 97.67%Couleur et forme :SolidMasse moléculaire :594.75Ref: TM-T8544
5mg35,00€10mg51,00€25mg77,00€50mg95,00€100mg144,00€200mg225,00€500mg373,00€1mL*10mM (DMSO)49,00€Ripretinib
CAS :Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formule :C24H21BrFN5O2Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :510.36Ref: TM-T8482
1mg80,00€5mg167,00€10mg281,00€25mg500,00€50mg727,00€100mg1.198,00€200mg1.596,00€1mL*10mM (DMSO)213,00€Cabozantinib hydrochloride
CAS :Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formule :C28H25ClFN3O5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :537.96Ref: TM-T5164
1mg44,00€2mg55,00€5mg69,00€10mg97,00€25mg169,00€50mg248,00€100mg349,00€200mg568,00€500mg908,00€c-Kit-IN-2
CAS :c-Kit-IN-2 is a c-KIT inhibitor (IC50: 82 nM), shows superior antiproliferative activities against all the three GIST cell lines, GIST430, GIST882, and GIST48 (Formule :C25H29N9O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.62c-Kit Protein, Human, Recombinant (His)
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :99.4%Couleur et forme :Lyophilized PowderMasse moléculaire :56.7 kDa (predicted); 86 kDa (reducing condition, due to glycosylation)Telatinib
CAS :Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Formule :C20H16ClN5O3Degré de pureté :97.61% - 99.81%Couleur et forme :SolidMasse moléculaire :409.83JNJ-38158471
CAS :JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formule :C15H17ClN6O3Degré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :364.79Ref: TM-T22349
1mg52,00€2mg74,00€5mg105,00€10mg156,00€25mg259,00€50mg378,00€100mg509,00€200mg698,00€1mL*10mM (DMSO)113,00€M4205
CAS :M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Formule :C29H32N8ODegré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :508.62Ref: TM-T9689
1mg52,00€5mg116,00€10mg178,00€25mg306,00€50mg437,00€100mg605,00€200mg815,00€1mL*10mM (DMSO)129,00€Motesanib Diphosphate
CAS :Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFormule :C22H23N5O·2H3PO4Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :569.44Anti-C-Kit Antibody (2T761)
Anti-C-Kit Antibody (2T761) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (2T761) can be used in ELISA(Det).Couleur et forme :Odour LiquidPLX647
CAS :PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Formule :C21H17F3N4Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :382.38Ref: TM-T1925
2mg42,00€5mg60,00€10mg90,00€25mg134,00€50mg188,00€100mg279,00€200mg411,00€1mL*10mM (DMSO)64,00€AST 487
CAS :AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formule :C26H30F3N7O2Degré de pureté :98.17% - 99.56%Couleur et forme :SolidMasse moléculaire :529.56Ref: TM-T4053
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg187,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)92,00€Pazopanib
CAS :Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formule :C21H23N7O2SDegré de pureté :98.78% - 99.72%Couleur et forme :White PowderMasse moléculaire :437.52Ref: TM-T0097L
10mg49,00€25mg73,00€50mg96,00€100mg145,00€200mg236,00€500mg331,00€1mL*10mM (DMSO)59,00€Anti-C-Kit Antibody (3B930)
Anti-C-Kit Antibody (3B930) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3B930) can be used in WB,ELISA,IP.Couleur et forme :Odour Liquid
