c-Kit
Les inhibiteurs de c-Kit sont des composés qui bloquent l'activité du Récepteur du Facteur de Cellules Souches (c-Kit), une tyrosine kinase jouant un rôle crucial dans la survie, la prolifération et la différenciation cellulaires, en particulier dans les cellules hématopoïétiques. Les mutations de c-Kit sont liées à divers cancers, notamment les tumeurs stromales gastro-intestinales (GIST) et la leucémie. Chez CymitQuimica, nous proposons des inhibiteurs de c-Kit pour soutenir vos recherches en oncologie, hématologie et biologie des cellules souches.
Produits appartenant à la catégorie "c-Kit"
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BLU-263
CAS :BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.Formule :C27H29FN10ODegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :528.58Ki20227
CAS :Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formule :C24H24N4O5SDegré de pureté :97.16% - 99.37%Couleur et forme :SolidMasse moléculaire :480.54Ref: TM-T4315
1mg47,00€5mg96,00€10mg154,00€25mg283,00€50mg464,00€100mg740,00€200mg1.008,00€1mL*10mM (DMSO)96,00€Anti-C-Kit Antibody (3F840)
Anti-C-Kit Antibody (3F840) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3F840) can be used in ELISA,IHC-P.Couleur et forme :Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.Couleur et forme :Odour Liquidc-Kit Protein, Human, Recombinant (hFc)
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Degré de pureté :97.1%Couleur et forme :Lyophilized PowderMasse moléculaire :82 kDa (predicted); 93-115 kDa (reducing conditions)Anti-C-Kit Antibody (3N57)
Anti-C-Kit Antibody (3N57) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3N57) can be used in ELISA(Cap).Couleur et forme :Odour LiquidBezuclastinib
CAS :Bezuclastinib (CGT9486) is a novel, potent and highly selective tyrosine kinase and c-kit D816V inhibitor for the study of advanced mastocytosis.Formule :C19H17N5ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :331.37AZD2932
CAS :AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formule :C24H25N5O4Degré de pureté :97.71% - 98.37%Couleur et forme :SolidMasse moléculaire :447.49Dovitinib
CAS :Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.Formule :C21H21FN6ODegré de pureté :99.66% - 99.78%Couleur et forme :SolidMasse moléculaire :392.43Ref: TM-T6289
5mg47,00€10mg70,00€25mg126,00€50mg202,00€100mg328,00€200mg490,00€500mg783,00€1mL*10mM (DMSO)50,00€KG5
CAS :KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).Formule :C20H16F3N7OSDegré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :459.45Ref: TM-T41003
1mg34,00€2mg47,00€5mg74,00€10mg105,00€25mg205,00€50mg313,00€100mg449,00€200mg628,00€1mL*10mM (DMSO)89,00€Pexidartinib
CAS :Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormule :C20H15ClF3N5Degré de pureté :98.34% - 99.51%Couleur et forme :SolidMasse moléculaire :417.81Ref: TM-T2115
5mg48,00€10mg62,00€25mg95,00€50mg120,00€100mg154,00€200mg202,00€500mg350,00€1mL*10mM (DMSO)52,00€Chiauranib
CAS :Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formule :C27H21N3O3Degré de pureté :96.25%Couleur et forme :SolidMasse moléculaire :435.47Ref: TM-T35570
1mg90,00€5mg187,00€10mg305,00€25mg520,00€50mg748,00€100mg1.026,00€1mL*10mM (DMSO)215,00€Anti-C-Kit Antibody-PE (1R766)
Anti-C-Kit Antibody-PE (1R766) is a PE-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-PE (1R766) can be used in FCM.Couleur et forme :Odour LiquidMulti-kinase inhibitor 1
CAS :Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formule :C20H17F3N4O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :418.37CHMFL-ABL/KIT-155
CAS :CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).Formule :C33H38F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :609.68CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Couleur et forme :Lyophilized PowderMasse moléculaire :56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.c-Kit Protein, Mouse, Recombinant (His)
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :98.2%Couleur et forme :Lyophilized PowderMasse moléculaire :57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)Anti-C-Kit Antibody-APC (8E724)
Anti-C-Kit Antibody-APC (8E724) is a APC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-APC (8E724) can be used in FCM.Couleur et forme :Odour LiquidDovitinib lactate hydrate
CAS :Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51ISCK03
CAS :ISCK03 is a selective SCF/c-Kit inhibitor.Formule :C19H21N3O2SDegré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :355.45
