Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
Produits appartenant à la catégorie "Signalisation du cytosquelette"
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PKCθ pseudosubstrate peptide inhibitor,myristoylated
Myristoylated PKCθ pseudosubstrate peptide inhibitor is a synthetic peptide utilized to investigate the mechanism of action of protein kinase C theta (PKCθ) [1Formule :C105H184N36O21SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2318.88Miransertib
CAS :Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.Formule :C27H24N6Degré de pureté :98.83% - ≥95%Couleur et forme :SolidMasse moléculaire :432.52Ref: TM-T3467
1mg52,00€5mg97,00€10mg169,00€25mg344,00€50mg567,00€100mg908,00€500mg1.795,00€1mL*10mM (DMSO)114,00€Defactinib hydrochloride
CAS :Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.Formule :C20H22ClF3N8O3SDegré de pureté :98.06% - 98.78%Couleur et forme :SolidMasse moléculaire :546.95Midostaurin
CAS :PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formule :C35H30N4O4Degré de pureté :100% - 99.47%Couleur et forme :SolidMasse moléculaire :570.64Ref: TM-T3211
1mg51,00€5mg88,00€10mg126,00€25mg216,00€50mg328,00€100mg487,00€500mg1.093,00€1mL*10mM (DMSO)96,00€LY3372689
CAS :LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.Formule :C16H22FN5O3SDegré de pureté :99.27% - 99.45%Couleur et forme :SolidMasse moléculaire :383.44Ref: TM-T61661
1mg99,00€5mg235,00€10mg354,00€25mg635,00€50mg935,00€100mg1.415,00€1mL*10mM (DMSO)259,00€Multi-kinase inhibitor 1
CAS :Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formule :C20H17F3N4O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :418.37FRAX597
CAS :FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).Formule :C29H28ClN7OSDegré de pureté :97.34% - 99.85%Couleur et forme :SolidMasse moléculaire :558.1Ansamitocin P 3'
CAS :Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.Formule :C32H43ClN2O9Degré de pureté :98.16% - 99.16%Couleur et forme :SolidMasse moléculaire :635.14Ref: TM-T1910
2mg34,00€5mg50,00€10mg84,00€25mg145,00€50mg229,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)70,00€Ifebemtinib
CAS :Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.Formule :C28H28F4N6O4Degré de pureté :98.07% - 99.82%Couleur et forme :SolidMasse moléculaire :588.55Ionomycin calcium
CAS :Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.Formule :C41H70CaO9Degré de pureté :98% - 98.11%Couleur et forme :SolidMasse moléculaire :747.07NAMI-A
CAS :NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.Formule :C8H15Cl4N4ORuSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.18Ipfencarbazone
CAS :Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.Formule :C18H14Cl2F2N4O2Couleur et forme :SolidMasse moléculaire :427.23Dynapyrazole A
CAS :Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).Formule :C20H12ClIN4ODegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :486.69RWJ 50271
CAS :RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formule :C18H17F3N4O2SDegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :410.41Ref: TM-T12783
1mg127,00€5mg311,00€10mg472,00€25mg747,00€50mg1.017,00€100mg1.311,00€200mg1.786,00€1mL*10mM (DMSO)344,00€AMP-945
CAS :AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.Formule :C28H32F3N5O2Degré de pureté :99.60%Couleur et forme :SolidMasse moléculaire :527.58Ref: TM-T9576
1mg97,00€5mg188,00€10mg311,00€25mg533,00€50mg755,00€100mg1.035,00€1mL*10mM (DMSO)254,00€Etrolizumab
CAS :MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.Degré de pureté :95% - 95%Couleur et forme :LiquidAdhesamine diTFA
CAS :Adhesamine diTFA, a dumbbell-shaped molecule, activates the MAPK/FAK pathway. It promotes adhesion and growth in mammalian cells and accelerates differentiation and enhances the survival rate of primary cultured mouse hippocampal neurons.Formule :C28H32Cl2F6N8O6S2Couleur et forme :SolidMasse moléculaire :825.63BX-2819
CAS :BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .Formule :C21H24N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.51αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Formule :C28H35F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.67Hydroxy-Dynasore
CAS :Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,Formule :C18H14N2O5Degré de pureté :100% - 97.60%Couleur et forme :SolidMasse moléculaire :338.31Ref: TM-T6822
5mg50,00€10mg84,00€25mg137,00€50mg221,00€100mg329,00€200mg490,00€500mg783,00€1mL*10mM (DMSO)55,00€αvβ6-IN-1
αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.Formule :C25H32F2N4O3Couleur et forme :SolidMasse moléculaire :474.5416-38-Thymosin β4 (cattle) (TFA)
Thymosin β4 (cattle) TFA is a high-affinity activator of MLCK that operates independently of Ca2+ [1].Formule :C120H205F3N32O43Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2841.1K858 (Racemic)
CAS :K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formule :C13H15N3O2SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :277.34AZ13705339
CAS :AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM.Formule :C33H36FN7O3SDegré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :629.75FAK-IN-7
CAS :FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.Formule :C16H13N3OSDegré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :295.36AJH-836
CAS :AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation ofFormule :C22H38O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.5310-Deacetyltaxol
CAS :10-Deacetyltaxol (10-DAT) is extracted from Taxus brevifolia barks.Formule :C45H49NO13Degré de pureté :94.63% - 99.93%Couleur et forme :SolidMasse moléculaire :811.87Tadocizumab
CAS :Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.Couleur et forme :LiquidKNK437
CAS :KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).Formule :C13H11NO4Degré de pureté :98.90%Couleur et forme :SolidMasse moléculaire :245.23PKC-IN-1
CAS :PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,Formule :C25H37FN8O2Degré de pureté :98% - 98.79%Couleur et forme :SolidMasse moléculaire :500.61Gamitrinib TPP
CAS :Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.Formule :C52H65N3O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :891.078API-1
CAS :API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .Formule :C13H15N5O6Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :337.29Ref: TM-T8969
1mg59,00€5mg125,00€10mg207,00€25mg376,00€50mg562,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)133,00€AKT-IN-1
CAS :AKT-IN-1 (AZD-26) is an allosteric AKT inhibitor (IC50: 1.04 μM).Formule :C22H21N3ODegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :343.42Ref: TM-T4489
1mg113,00€2mg158,00€5mg235,00€10mg400,00€25mg652,00€50mg909,00€100mg1.225,00€1mL*10mM (DMSO)188,00€HSP70/SIRT2-IN-2
CAS :HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].Formule :C17H13N3S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.5LXH254
CAS :LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formule :C25H25F3N4O4Degré de pureté :98.3% - 99.92%Couleur et forme :SolidMasse moléculaire :502.49Ref: TM-T11898
1mg52,00€5mg122,00€10mg185,00€25mg363,00€50mg567,00€100mg690,00€200mg948,00€500mg1.444,00€1mL*10mM (DMSO)135,00€Debio 0932
CAS :Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.Formule :C22H30N6O2SDegré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :442.58AT9283
CAS :AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43Ref: TM-T3068
1mg47,00€2mg60,00€5mg95,00€10mg170,00€25mg299,00€50mg499,00€100mg723,00€1mL*10mM (DMSO)97,00€Bisindolylmaleimide III
CAS :Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6Formule :C23H20N4O2Degré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :384.43Pifithrin-μ
CAS :Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Formule :C8H7NO2SDegré de pureté :99.33% - 99.79%Couleur et forme :SolidMasse moléculaire :181.21KP-23172
CAS :KP-23172 is a inhibitor of PI3-K/Akt pathway.Formule :C10H4N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :224.18ML346
CAS :ML346 is a novel activator of Hsp70.Formule :C14H12N2O4Degré de pureté :99.25% - 99.29%Couleur et forme :SolidMasse moléculaire :272.26Ref: TM-T3594
1mg40,00€2mg52,00€5mg85,00€10mg115,00€25mg172,00€50mg274,00€100mg427,00€500mg938,00€1mL*10mM (DMSO)85,00€Degrasyn
CAS :Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.Formule :C19H18BrN3ODegré de pureté :98.32% - 99.98%Couleur et forme :SolidMasse moléculaire :384.27Ref: TM-T6300
2mg44,00€5mg64,00€10mg97,00€25mg198,00€50mg340,00€100mg532,00€200mg747,00€1mL*10mM (DMSO)69,00€Phorbol 12,13-dibutyrate
CAS :Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formule :C28H40O8Degré de pureté :100% - 99.32%Couleur et forme :SolidMasse moléculaire :504.61Ref: TM-T16526
1mg62,00€5mg169,00€10mg283,00€25mg557,00€50mg795,00€100mg1.074,00€1mL*10mM (DMSO)180,00€Akt3 degrader 1
CAS :Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.Formule :C53H72N8O4Degré de pureté :98.18% - 99.14%Couleur et forme :SolidMasse moléculaire :885.19VTX-27
CAS :VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).Formule :C20H24ClFN6ODegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :418.9Ref: TM-T13314
1mg93,00€2mg125,00€5mg244,00€10mg364,00€25mg562,00€50mg780,00€100mg1.035,00€1mL*10mM (DMSO)225,00€Ruboxistaurin hydrochloride
CAS :Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.Formule :C28H28N4O3·HClDegré de pureté :98.44% - 99.22%Couleur et forme :SolidMasse moléculaire :505.01Ref: TM-T3689
1mg71,00€2mg93,00€5mg157,00€10mg256,00€25mg513,00€50mg740,00€100mg1.035,00€500mg2.072,00€1mL*10mM (DMSO)202,00€Imatinib
CAS :Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormule :C29H31N7ODegré de pureté :100% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.6Tetradecyltrimethylammonium bromide
CAS :Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.Formule :C17H38BrNDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :336.39K-252b
CAS :K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor.Formule :C26H19N3O5Degré de pureté :98%Couleur et forme :Ready-To-Use SolutionMasse moléculaire :453.45Larazotide acetate
CAS :Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Formule :C34H59N9O12Degré de pureté :95.53%Couleur et forme :SolidMasse moléculaire :785.89para-Nitroblebbistatin
CAS :para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.Cost-effective and quality-assured.Formule :C18H15N3O4Degré de pureté :100% - 99.92%Couleur et forme :SolidMasse moléculaire :337.33Ref: TM-T12360
1mg87,00€5mg212,00€10mg316,00€25mg512,00€50mg695,00€100mg940,00€200mg1.264,00€1mL*10mM (DMSO)215,00€Chromeceptin
CAS :Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.Formule :C19H16F3N3ODegré de pureté :99.72%Couleur et forme :SoildMasse moléculaire :359.35Ref: TM-T60055
5mg50,00€10mg74,00€25mg140,00€50mg197,00€100mg306,00€200mg442,00€1mL*10mM (DMSO)51,00€PU-H71
CAS :PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.Formule :C18H21IN6O2SDegré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :512.37Delcasertib
CAS :Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Formule :C120H199N45O34S2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :2880.28Ref: TM-T11740
1mg202,00€5mg512,00€10mg740,00€25mg1.121,00€50mg1.539,00€100mg2.072,00€1mL*10mM (DMSO)1.691,00€1-Oleoyl-2-acetyl-sn-glycerol
CAS :1-Oleoyl-2-acetyl-sn-glycerol (1-oleoyl-2-acetyl-glycerol) is a PKC activator that induces superoxide production.Formule :C23H42O5Couleur et forme :SolidMasse moléculaire :398.58Nilotinib hydrochloride
CAS :Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.Formule :C28H23ClF3N7ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :565.98Hispidin
CAS :Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective propertiesFormule :C13H10O5Degré de pureté :98.27%Couleur et forme :White Crystalline PowderMasse moléculaire :246.22Ref: TM-T7792
1mg88,00€5mg187,00€10mg298,00€25mg533,00€50mg747,00€100mg1.017,00€1mL*10mM (DMSO)207,00€SB-743921 hydrochloride
CAS :SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).Formule :C31H34Cl2N2O3Degré de pureté :95.58% - 99.70%Couleur et forme :SolidMasse moléculaire :553.52Ref: TM-T2255
1mg42,00€5mg106,00€10mg163,00€25mg278,00€50mg429,00€100mg657,00€500mg1.501,00€1mL*10mM (DMSO)130,00€PPY A
CAS :PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl gene-transformed cellsFormule :C22H20N4O2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :372.42ILK-IN-2
CAS :ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.Formule :C30H30F3N5ODegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :533.59Ref: TM-T5488
1mg48,00€5mg97,00€10mg128,00€25mg162,00€50mg192,00€100mg281,00€200mg408,00€1mL*10mM (DMSO)137,00€Rosabulin
CAS :v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency.Formule :C22H16N4O2SDegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :400.45Ref: TM-T16788
1mg97,00€5mg243,00€10mg364,00€25mg658,00€50mg938,00€100mg1.415,00€1mL*10mM (DMSO)265,00€Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Formule :C17H31N7O10Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :493.47Hsp90-IN-34
CAS :Hsp90-IN-34 (compound HAM-1) is a chemical inhibitor that targets the Aha1-Hsp90 chaperone complex with high affinity (KDapp=23.5 µM). It modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1.Formule :C22H14F2N6OCouleur et forme :SolidMasse moléculaire :416.38Mivobulin
CAS :Mivobulin is an inhibitor of tubulin .Formule :C17H19N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.37FPA-124
CAS :FPA-124 is a cell-permeable copper complex that acts as a selective Akt (protein kinase B) inhibitor to induce apoptosis in a variety of cancer cell lines.Formule :C11H9Cl2CuN3O2SDegré de pureté :95.04%Couleur et forme :SolidMasse moléculaire :381.73ZLY06
CAS :ZLY06 is a dual agonist of peroxisome proliferator-activated receptors (PPAR) δ and γ with oral activity (PPAR δ: EC50=341 nM; PPARγ: EC50=237 nM). It mediates the upregulation of CD36 and induces hepatic lipid accumulation by inhibiting the phosphorylation of AKT1. Moreover, ZLY06 significantly improves glucose and lipid metabolism without increasing body weight, primarily by enhancing the β-oxidation of fatty acids and reducing hepatic lipid synthesis, thereby alleviating fatty liver disease.Formule :C25H26O6Couleur et forme :SolidMasse moléculaire :422.47ATN-161 trifluoroacetate salt
CAS :ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formule :C25H36F3N9O10SDegré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :711.67PND-1186
CAS :PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formule :C25H26F3N5O3Degré de pureté :99.14% - 99.75%Couleur et forme :SolidMasse moléculaire :501.5Catumaxomab
CAS :Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.Degré de pureté :95%Couleur et forme :LiquidCK-869
CAS :CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.Formule :C17H16BrNO3SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :394.28Zelavespib hydrochloride
Zelavespib (PU-H71) hydrochloride is a potent inhibitor of Hsp90, exhibiting an IC50 value of 51 nM in MDA-MB-468 cells.Degré de pureté :98%Couleur et forme :Odour SolidSC79
CAS :SC79 is an AKT agonist with specificity and blood-brain barrier permeability.Formule :C17H17ClN2O5Degré de pureté :98% - 99.93%Couleur et forme :SolidMasse moléculaire :364.78β-glycosidase-IN-1
CAS :β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.Formule :C13H23NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :273.33A-3 hydrochloride
CAS :A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formule :C12H14Cl2N2O2SDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :321.22Ref: TM-T14069
1mg35,00€5mg66,00€10mg96,00€25mg170,00€50mg274,00€100mg439,00€500mg938,00€1mL*10mM (DMSO)90,00€(8R)-8-Hydroxyepoxyboetirane A
(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.Couleur et forme :Odour SolidTASP0415914
CAS :TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). TFormule :C13H17N5O3SDegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :323.37Ref: TM-T7879
1mg55,00€5mg117,00€10mg187,00€25mg315,00€50mg449,00€100mg620,00€200mg835,00€1mL*10mM (DMSO)134,00€Orbofiban TFA
CAS :Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormule :C19H24F3N5O6Degré de pureté :97.45% - 98.43%Couleur et forme :SolidMasse moléculaire :475.42HSP27 inhibitor J2
CAS :HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function ofFormule :C13H12O4SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :264.3Ref: TM-T7265
1mg130,00€2mg185,00€5mg311,00€10mg472,00€25mg753,00€50mg1.064,00€100mg1.415,00€1mL*10mM (DMSO)455,00€Firategrast
CAS :Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFormule :C27H27F2NO6Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :499.5Ref: TM-TQ0291
1mg47,00€5mg87,00€10mg140,00€25mg283,00€50mg464,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)97,00€Vevorisertib trihydrochloride
CAS :Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is ainhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3.Formule :C35H41Cl3N8ODegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :696.12Ref: TM-T38846
1mg70,00€5mg149,00€10mg230,00€25mg393,00€50mg552,00€100mg740,00€200mg1.130,00€1mL*10mM (DMSO)212,00€Teprenone
CAS :Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).Formule :C23H38ODegré de pureté :99.76% - 99.96%Couleur et forme :SolidMasse moléculaire :330.55FAK-IN-14
CAS :FAK-IN-14 is a FAK inhibitor that induces apoptosis and cell cycle arrest. FAK-IN-14 has a more significant inhibitory effect on FAK, FGFR1 and Pyk2.Formule :C21H24BrN7OSDegré de pureté :99.7%Couleur et forme :SoildMasse moléculaire :502.43BNC105
CAS :BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formule :C20H20O7Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :372.37Ref: TM-T14694
1mg84,00€5mg160,00€10mg226,00€25mg371,00€50mg520,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)170,00€Teclistamab
CAS :Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.Degré de pureté :95%Couleur et forme :LiquidPentachloropseudilin
CAS :Pentachloropseudilin inhibits Myosin-1 and speeds up TGF-β receptor turnover, suppressing TGF-β activity.Formule :C10H4Cl5NODegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :331.41PF-562271
CAS :PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).Formule :C21H20F3N7O3SDegré de pureté :100% - 97.65%Couleur et forme :SolidMasse moléculaire :507.49Ref: TM-T2465
1mg59,00€5mg127,00€10mg159,00€25mg240,00€50mg378,00€100mg567,00€200mg793,00€1mL*10mM (DMSO)140,00€Akt1 and Akt2-IN-1
CAS :Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.Formule :C33H29N7OCouleur et forme :SolidMasse moléculaire :539.63cSRC/BCR-ABL-IN-1
cSRC/BCR-ABL-IN-1 (compound 21b) is a potent inhibitor of Bcr-Abl and C-Src, with IC50 values of 56.2 nM and 101 nM, respectively. It exhibits cytotoxicity.Formule :C29H31Cl2N5O4Masse moléculaire :584.494ε-V1-2, Cys-conjugated
Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor.Formule :C40H70N10O14SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :947.11Miltefosine
CAS :Miltefosine (HePC), effective oral drug for both visceral and cutaneous leishmaniasis, in clinical trials worldwide.Formule :C21H46NO4PDegré de pureté :98% - 99.87%Couleur et forme :White To Off-White PowderMasse moléculaire :407.57SMTIN-T140
CAS :SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Formule :C36H34BrClFN5OPDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :718.02HA-100
CAS :HA-100 is an inhibitor of protein kinaseFormule :C13H15N3O2SDegré de pureté :99.44%Couleur et forme :Pale Yellow Crystalline SolidMasse moléculaire :277.3420-HETE
CAS :20-HETE is a CYP450 product, vasoconstrictor, modulates K+ channels, affects NADPH, ROS, NF-κB, NO synthase, and cell apoptosis/proliferation.Formule :C20H32O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :320.47Ref: TM-T14021
1mg (312.04μM*10mL in Ethanol)1.139,00€5mg (312.04μM*50mL in Ethanol)2.327,00€100μg (312.04μM*1mL in Ethanol)474,00€PKCiota-IN-2
CAS :PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).Formule :C24H21N5ODegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :395.46Ref: TM-T9863
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€1mL*10mM (DMSO)279,00€(E)-Akt inhibitor-IV
CAS :(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt.Formule :C31H29IN4SDegré de pureté :99.01% - 99.74%Couleur et forme :SolidMasse moléculaire :616.56Ref: TM-T9393
1mg55,00€5mg116,00€10mg180,00€25mg338,00€50mg469,00€100mg655,00€200mg924,00€1mL*10mM (DMSO)157,00€Eupalinolide A
CAS :Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.Formule :C24H30O9Degré de pureté :98.18% - 99.22%Couleur et forme :SolidMasse moléculaire :462.49Taurochenodeoxycholic acid sodium
CAS :Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formule :C26H44NNaO6SDegré de pureté :98.23% - 99.45%Couleur et forme :White To Off-White PowderMasse moléculaire :521.68Arimoclomol maleate
CAS :Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Formule :C18H24ClN3O7Degré de pureté :99.9% - 99.98%Couleur et forme :SolidMasse moléculaire :429.85Ombrabulin hydrochloride
CAS :Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells andFormule :C21H27ClN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.9Roslin 2 bromide
CAS :Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5.Formule :C13H19BrN4Degré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :311.22FRAX486
CAS :FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.Formule :C25H23Cl2FN6ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :513.39AKT-IN-26
CAS :AKT-IN-26 (Compound 453) is an AKT inhibitor that binds to the Pleckstrin Homology (PH) domain of AKT. It is useful for research related to cell proliferation and cancer involving the AKT pathway.Formule :C21H17N5O4SCouleur et forme :SolidMasse moléculaire :435.456JG-231
CAS :JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.Formule :C22H18BrCl2N3OS4Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :619.47TN-16
CAS :TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)Formule :C19H18N2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :306.36LXW7
CAS :LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Formule :C29H48N12O12S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :820.89Batatasin III
CAS :Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancerFormule :C15H16O3Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :244.29HM03
CAS :HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.Formule :C26H27ClN4O2Degré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :462.97AT7867
CAS :AT7867 inhibits Akt1/2/3 & p70S6K/PKA (IC50: 32/17/47 nM & 85/20 nM), minimal effect beyond AGC kinases.Formule :C20H20ClN3Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :337.85Ref: TM-T6304
2mg44,00€5mg65,00€10mg86,00€25mg135,00€50mg210,00€100mg313,00€200mg452,00€1mL*10mM (DMSO)65,00€2-Methylbutyrylcarnitine chloride
2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.Formule :C12H24ClNO4Couleur et forme :SolidMasse moléculaire :281.78Arginine-glycine-aspartic acid
CAS :RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formule :C12H22N6O6Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :346.34Valategrast hydrochloride
CAS :Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formule :C30H33Cl4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.41Irigenin
CAS :Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormule :C18H16O8Degré de pureté :99.50% - 99.85%Couleur et forme :SolidMasse moléculaire :360.31Afuresertib hydrochloride
CAS :Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)Formule :C18H18Cl3FN4OSDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :463.8Ref: TM-T7885
2mg52,00€5mg74,00€10mg95,00€25mg163,00€50mg253,00€100mg437,00€200mg568,00€1mL*10mM (DMSO)86,00€Bersanlimab
CAS :Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.22 kDaDolastatin 10
CAS :Dolastatin 10 (DLS 10) is a powerful peptide with antimitotic properties, effectively inhibiting tubulin polymerization.Formule :C42H68N6O6SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :785.09Shepherdin 79-87 acetate
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.Formule :C43H68N12O14SDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :1009.14G-5555
CAS :G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).Formule :C25H25ClN6O3Degré de pureté :99.76% - 99.87%Couleur et forme :SolidMasse moléculaire :492.96Flumatinib
CAS :Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Formule :C29H29F3N8ODegré de pureté :99.52% - 99.95%Couleur et forme :SolidMasse moléculaire :562.59Ref: TM-T4320
1mg35,00€5mg66,00€10mg87,00€25mg127,00€50mg163,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)87,00€Betamethasone 17-benzoate
CAS :Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).Formule :C29H33FO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :496.57EC 144
CAS :EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.Formule :C21H24ClN5O2Couleur et forme :SolidMasse moléculaire :413.9BRD9876
CAS :BRD9876 is a selective inhibitor of MM1S growth.Formule :C16H14N2Degré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :234.3FAK-IN-15
FAK-IN-15 is a highly potent focal adhesion kinase (FAK) inhibitor with antitumor activity.Formule :C21H24ClN7OSDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :457.98Palmitic acid
CAS :Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.Formule :C16H32O2Degré de pureté :99.17% - 99.67%Couleur et forme :White Crystalline Scales SolidMasse moléculaire :256.42Cyclo(RADfK)
CAS :Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Formule :C28H43N9O7Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :617.7Auristatin F
CAS :Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.Formule :C40H67N5O8Degré de pureté :98.41% - 99.25%Couleur et forme :SolidMasse moléculaire :745.99AM-5308
CAS :AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.Formule :C26H35N5O5SDegré de pureté :98.06% - 99.58%Couleur et forme :SolidMasse moléculaire :529.65MMAF
CAS :MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.Formule :C39H65N5O8Degré de pureté :97.00%Couleur et forme :SolidMasse moléculaire :731.96GRGDSPK
CAS :GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.Formule :C28H49N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :715.76Amiprofos methyl
CAS :Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.Formule :C11H17N2O4PSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :304.3Elarofiban
CAS :Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Formule :C22H32N4O4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :416.51cemadotin free base
CAS :Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocksFormule :C35H56N6O5Degré de pureté :99% - 99.69%Couleur et forme :SolidMasse moléculaire :640.86JH-VIII-157-02
CAS :JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.Formule :C28H27N5O2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :465.55Ref: TM-T15612
1mg116,00€5mg240,00€10mg358,00€25mg558,00€50mg753,00€100mg1.035,00€1mL*10mM (DMSO)246,00€N-Desmethyltamoxifen hydrochloride
CAS :N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Formule :C25H28ClNODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :393.95Ref: TM-T12148
2mg35,00€5mg52,00€10mg78,00€25mg139,00€50mg202,00€100mg305,00€200mg426,00€1mL*10mM (DMSO)52,00€Dasatinib monohydrate
CAS :Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formule :C22H28ClN7O3SDegré de pureté :100% - 99.68%Couleur et forme :SolidMasse moléculaire :506.03Bisindolylmaleimide I
CAS :Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formule :C25H24N4O2Degré de pureté :98.19% - 99.08%Couleur et forme :Orange SolidMasse moléculaire :412.48C086
CAS :C086 is a novel and potent Hsp90 inhibitor that suppresses cell cycle progression, induces apoptosis, and exhibits anti-metastatic properties by modulating various mechanisms in different cell types.Formule :C29H28O8Couleur et forme :SolidMasse moléculaire :504.53Mertansine
CAS :Mertansine is a tubulin inhibitor and an antibody-conjugable maytansinoid alkaloid. The IC50 of Mertansine against HCT-15 and A431 cells is 0.750 and 0.04nM.Cost-effective and quality-assured.Formule :C35H48ClN3O10SDegré de pureté :100% - 99.76%Couleur et forme :SolidMasse moléculaire :738.29SB273005
CAS :SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.Formule :C22H24F3N3O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :451.44Dynasore
CAS :Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Formule :C18H14N2O4Degré de pureté :95.85% - 99.22%Couleur et forme :SolidMasse moléculaire :322.31Ref: TM-T1848
5mg49,00€10mg79,00€25mg140,00€50mg259,00€100mg374,00€200mg560,00€500mg883,00€1mL*10mM (DMSO)87,00€c-ABL-IN-5
C-ABL-IN-5, a selective c-Abl inhibitor, exhibits neuroprotective properties and has favorable characteristics including blood-brain barrier permeability,Formule :C19H17F2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.35KIF18A-IN-14
CAS :KIF18A-IN-14 (Compound Example 81) is an inhibitor of KIF18A that exists in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit the viability of OVCAR-3 cells with IC50 values of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be utilized in tumor research, including studies on colon cancer, breast cancer, and lung cancer.Formule :C26H32F3N5O6SCouleur et forme :SolidMasse moléculaire :599.62REDV TFA
REDV TFA, the minimal active sequence of the CS5 site in the alternatively spliced type III connecting segment (IIICS) of fibronectin, mediates adhesion to theFormule :C20H35N7O9·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :517.53 (free acid)Lyn-IN-1
CAS :Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and LynFormule :C30H31F3N8ODegré de pureté :97% - 99.33%Couleur et forme :SolidMasse moléculaire :576.62Ref: TM-T11916
1mg47,00€2mg56,00€5mg84,00€10mg124,00€25mg250,00€50mg393,00€100mg560,00€200mg815,00€1mL*10mM (DMSO)97,00€PVZB1194
CAS :PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis throughFormule :C13H9F4NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.28Defactinib analogue-1
CAS :Defactinib analogue-1 (Compound 7) serves as a ligand for the target protein FAK, and is utilized in the synthesis of PROTAC FAK degrader 1.Formule :C20H20F3N5O3SCouleur et forme :SolidMasse moléculaire :467.47Tubulysin D
CAS :Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and displays potent antitumor activity.Formule :C43H65N5O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :828.07Triciribine
CAS :Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.Formule :C13H16N6O4Degré de pureté :99.01% - 99.87%Couleur et forme :SolidMasse moléculaire :320.3Ref: TM-T6065
1mg43,00€2mg57,00€5mg93,00€10mg135,00€25mg236,00€50mg394,00€100mg588,00€1mL*10mM (DMSO)93,00€S516
CAS :S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.Formule :C21H19N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.47Nic-15
CAS :Nic-15 (compound 4n) serves as an anti-constrictive agent targeting the low vascular characteristics of pancreatic tumors. These characteristics enable cancer cells to adapt to the nutrient-deficient tumor microenvironment and develop resistance to treatment. Nic-15 modulates the PI3K/Akt/mTOR pathway and alleviates ER stress induced by Gemcitabine. It significantly inhibits migration and colony formation in MIA PaCa-2 and PANC-1 pancreatic cancer cells. When used in combination with Gemcitabine, Nic-15 effectively addresses resistance issues in pancreatic tumors. In xenograft models in vivo, Nic-15 notably enhances the efficacy of Gemcitabine.Formule :C25H26F2O3Couleur et forme :SolidMasse moléculaire :412.47Dasatinib N-oxide
CAS :Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.Formule :C22H26ClN7O3SDegré de pureté :98.54% - 99.85%Couleur et forme :SolidMasse moléculaire :504Tubulin inhibitor 6
CAS :Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formule :C20H14ClNO2SDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :367.85Ref: TM-T13224
5mg50,00€10mg80,00€25mg117,00€50mg170,00€100mg259,00€200mg369,00€1mL*10mM (DMSO)51,00€PKC-θ inhibitor 1
CAS :PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)Formule :C17H15F3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.32FGFRs-IN-1
FGFRs-IN-1 (Compound A16) is an orally active inhibitor targeting FGFR1/2/3/4, with IC50 values of 2.3, 7, 11, and 163 nM respectively. It also inhibits VEGFR1/2/3, Abl, and Flt3, with IC50 values of 61, 176, 112, 26, and 353 nM. The compound shows weak inhibition of CYP enzymes. FGFRs-IN-1 reduces the expression of α-SMA and collagen I, and it inhibits epithelial-mesenchymal transition (EMT) in A549 cells stimulated by TGF-β1. Additionally, FGFRs-IN-1 demonstrates anti-inflammatory activity in mouse models of lung fibrosis induced by Bleomycin and liver fibrosis induced by CCl4.Formule :C28H26Cl2N4O3Couleur et forme :SolidMasse moléculaire :537.44HSP90-IN-27
CAS :HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].Formule :C18H21N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :343.44PF-431396
CAS :PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).Formule :C22H21F3N6O3SDegré de pureté :98.83% - 99.82%Couleur et forme :SolidMasse moléculaire :506.5Dynole 34-2
CAS :Dynole 34-2 is a non-competitive inhibitor of dynamin1 and dynamin2 GTPases that inhibits receptor-mediated endocytosis and synaptic vesicle endocytosis.Formule :C25H36N4ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :408.58Tonabersat
CAS :Tonabersat (SB-220453) is a novel and orally available gap-junction modulator and CSD (Cortical spreading depression) inhibitor that,migraine and epilepsy.Formule :C20H19ClFNO4Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :391.82Uprosertib
CAS :Uprosertib (GSK2141795) is a potent, selective Akt broad-spectrum inhibitor for Akt1/Akt2/Akt3.Cost-effective and quality-assured.Formule :C18H16Cl2F2N4O2Degré de pureté :95.62% - 99.54%Couleur et forme :SolidMasse moléculaire :429.25Ref: TM-T6849
1mg47,00€2mg59,00€5mg85,00€10mg124,00€25mg202,00€50mg324,00€100mg535,00€200mg752,00€1mL*10mM (DMSO)108,00€Xentuzumab
CAS :Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits AKT activation and can be used to study solid tumours.Degré de pureté :95% - > 95%Couleur et forme :LiquidMasse moléculaire :143.7 kDaEV206
CAS :EV206 is an effective inhibitor of Hsp70, exhibiting antiproliferative properties. This compound induces cell apoptosis (apoptosis) and enhances the protein expression of cleaved PARP and caspase-3. Additionally, EV206 demonstrates antitumor activity.Formule :C21H19N3OCouleur et forme :SolidMasse moléculaire :329.40ILK-IN-3
CAS :ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Formule :C10H12N6ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :232.24(±)-1,2-Diolein
CAS :(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Formule :C39H72O5Couleur et forme :SolidMasse moléculaire :620.99Alvespimycin
CAS :Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.Formule :C32H48N4O8Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :616.75IIQLPEIVVV TFA
IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.Formule :C54H95N11O14·xC2HF3O2Couleur et forme :SolidMasse moléculaire :1122.40 (free base)Tyrosine kinase-IN-9
CAS :Tyrosine kinase-IN-9 (Compound B) is an inhibitor of c-Abl. It is useful for studying neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.Formule :C20H14ClN3O3Couleur et forme :SolidMasse moléculaire :379.796PF-03814735
CAS :PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Formule :C23H25F3N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.48Tirofiban
CAS :Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Formule :C22H36N2O5SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :440.63-Hydroxyxanthone
CAS :3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical veinFormule :C13H8O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :212.2NPX800
CAS :NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.Formule :C32H32FN5O4Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :569.63Ref: TM-T9804
1mg96,00€5mg240,00€10mg375,00€25mg627,00€50mg893,00€100mg1.216,00€1mL*10mM (DMSO)300,00€AKT-IN-6
CAS :AKT-IN-6 (INCB-047775) inhibits Akt, a key signaling protein linked to type 2 diabetes and cancer.Formule :C22H20FN5ODegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :389.43Ref: TM-T36310
1mg35,00€5mg74,00€10mg111,00€25mg216,00€50mg354,00€100mg567,00€200mg805,00€1mL*10mM (DMSO)84,00€Radicicol
CAS :Radicicol is an antifungal antibiotic, a inhibitor of Hsp90 & FTO, Anti-malarial , inhibits iNOS gene expression by blocking the p38 kinase and NF-κB/Rel.Formule :C18H17ClO6Degré de pureté :98%Couleur et forme :White/Yellow PowderMasse moléculaire :364.78Phorbol 12-myristate 13-acetate
CAS :Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Formule :C36H56O8Degré de pureté :100% - 99.5%Couleur et forme :White To Off-White SolidMasse moléculaire :616.83Eg5 Inhibitor V, trans-24
CAS :Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Formule :C26H21N3O3Degré de pureté :97.45%Couleur et forme :SolidMasse moléculaire :423.46Ref: TM-T11155
1mg92,00€5mg205,00€10mg305,00€25mg495,00€50mg677,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)227,00€A-286982
CAS :A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.Formule :C24H27N3O4SDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :453.55Ref: TM-T21781
1mg35,00€2mg50,00€5mg74,00€10mg107,00€25mg210,00€50mg350,00€100mg522,00€1mL*10mM (DMSO)81,00€BX517
CAS :BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.Formule :C15H14N4O2Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :282.3DTHIB
CAS :DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.Formule :C13H9ClFN3O3Degré de pureté :98.86% - 99.29%Couleur et forme :SolidMasse moléculaire :309.68Ref: TM-T8858
1mg35,00€5mg70,00€10mg104,00€25mg210,00€50mg338,00€100mg540,00€500mg1.130,00€1mL*10mM (DMSO)78,00€AN-019
CAS :AN-019 (NRC-019) is a Bcr-Abl kinase inhibitor with antitumor activity for the study of chronic myelogenous leukemia (CML) and breast cancer.Formule :C25H17F6N5ODegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :517.43ZIP acetate(863987-12-6 free base)
ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an IC50 of 1-2.5 μM.Formule :C92H158N30O19Degré de pureté :94.68%Couleur et forme :SolidMasse moléculaire :1988.43Tilavonemab
CAS :Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Degré de pureté :95% - 95%Couleur et forme :LiquidSuprafenacine
CAS :Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that inducesFormule :C16H18N4ODegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :282.34GRGDSP acetate(91037-75-1 free base)
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.Formule :C24H41N9O12Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :647.64Auristatin E
CAS :Auristatin E, MMAE analog, blocks tubulin polymerisation, has cytotoxic and potent antitumor effects, used in ADCs.Formule :C40H69N5O7Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :732.01SB-216
CAS :SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.Formule :C17H18N4O2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :310.35Ref: TM-T60757
1mg54,00€5mg116,00€10mg188,00€25mg331,00€50mg475,00€100mg655,00€1mL*10mM (DMSO)133,00€Dynamin inhibitory peptide, myristoylated acetate
Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.Formule :C63H111N19O16Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :1390.67SC-10
CAS :SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.Formule :C17H22ClNO2SDegré de pureté :99.24% - 99.58%Couleur et forme :SolidMasse moléculaire :339.88GRP78-IN-3
CAS :GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Formule :C17H18N4O2SDegré de pureté :99.11%Couleur et forme :SoildMasse moléculaire :342.42ALK inhibitor 1
CAS :ALK inhibitor 1 is a selective ALK kinase inhibitor.Formule :C23H28BrN7O3SDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :562.48Ref: TM-T10285
1mg52,00€5mg116,00€10mg170,00€25mg340,00€50mg472,00€100mg645,00€1mL*10mM (DMSO)143,00€KIF18A-IN-3
CAS :KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Formule :C28H38N4O5S2Degré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :574.76Combretastatin A-1
CAS :Combretastatin A-1 is a microtubule inhibitor with anti-tumour and can be used to study liver cancer.Formule :C18H20O6Degré de pureté :97.49% - 97.49%Couleur et forme :SolidMasse moléculaire :332.35Lifitegrast
CAS :Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.Formule :C29H24Cl2N2O7SDegré de pureté :99.39% - 99.66%Couleur et forme :SolidMasse moléculaire :615.48CGP 53353
CAS :CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.Formule :C20H13F2N3O2Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :365.33PKC-θ inhibitor
CAS :PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.Formule :C20H25F3N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.45Ref: TM-T5423
1mg106,00€5mg250,00€10mg329,00€25mg467,00€50mg612,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)274,00€Borussertib
CAS :Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)Formule :C36H32N6O3Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :596.68Ref: TM-T8427
1mg133,00€5mg274,00€10mg432,00€25mg715,00€50mg1.008,00€100mg1.359,00€1mL*10mM (DMSO)360,00€FAK-IN-11
FAK-IN-11 (Compound 4l), a FAK inhibitor, specifically targets the ATP binding pocket of FAK to prevent its phosphorylation.Formule :C25H41NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :403.6Tirbanibulin Mesylate
CAS :Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formule :C27H33N3O6SDegré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :527.63Ref: TM-T15675
2mg38,00€5mg56,00€10mg70,00€25mg126,00€50mg243,00€100mg416,00€200mg562,00€1mL*10mM (DMSO)65,00€IPI-493
CAS :IPI-493 is a bioactive chemical.Formule :C28H39N3O8Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :545.62WAY-118959-A
CAS :WAY-118959-A is a potential microtubule acetylation inhibitor.Formule :C16H14N4OS2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :342.44Ref: TM-T60065
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)261,00€Sangivamycin
CAS :Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.Formule :C12H15N5O5Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :309.28Ref: TM-T9605
1mg126,00€5mg274,00€10mg416,00€25mg677,00€50mg944,00€100mg1.264,00€1mL*10mM (DMSO)360,00€AKT-IN-2
CAS :AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).Formule :C25H34F3N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.583CAI
CAS :3CAI inhibits AKT1/2, reduces mTOR/GSK3β, and triggers apoptosis in colon cancer cells.Formule :C10H8ClNODegré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :193.63Ref: TM-T14034
5mg55,00€10mg77,00€25mg125,00€50mg220,00€100mg330,00€200mg485,00€500mg787,00€1mL*10mM (DMSO)64,00€
