Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
Produits appartenant à la catégorie "Signalisation du cytosquelette"
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VER-49009
CAS :VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).Formule :C19H18ClN3O4Degré de pureté :99.36% - 99.99%Couleur et forme :SolidMasse moléculaire :387.82Ref: TM-T3454
2mg46,00€5mg64,00€10mg92,00€25mg164,00€50mg259,00€100mg354,00€200mg500,00€1mL*10mM (DMSO)52,00€GW406108X(Z/E)
CAS :GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .Formule :C20H11Cl2NO4Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :400.21Ref: TM-T9207L
1mg131,00€5mg286,00€10mg430,00€25mg647,00€50mg969,00€100mg1.301,00€1mL*10mM (DMSO)283,00€Valrubicin
CAS :Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Formule :C34H36F3NO13Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :723.64Tubulin inhibitor 8
CAS :Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.Formule :C21H14N2O3Degré de pureté :100% - 99.34%Couleur et forme :SolidMasse moléculaire :342.35TTBK1-IN-2
CAS :TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.Formule :C18H13ClN4ODegré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :336.77Ref: TM-T60086
1mg81,00€5mg168,00€10mg240,00€25mg399,00€50mg567,00€100mg758,00€200mg1.017,00€1mL*10mM (DMSO)170,00€Pimitespib
CAS :Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).Formule :C25H26N8ODegré de pureté :99.22% - 99.49%Couleur et forme :SolidMasse moléculaire :454.53P8RI acetate
P8RI acetate mimics CD31, activates CDP8RI, and suppresses the immune response by restoring CD31 pathway.Formule :C53H81N13O11Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :1076.29Paprotrain
CAS :Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formule :C16H11N3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :245.28Ref: TM-T12359
5mg48,00€10mg62,00€25mg97,00€50mg169,00€100mg250,00€200mg373,00€500mg612,00€1mL*10mM (DMSO)52,00€DDO-5936
CAS :DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.Formule :C25H29N5O4SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :495.59Ref: TM-T9202
1mg37,00€5mg80,00€10mg126,00€25mg264,00€50mg389,00€100mg553,00€200mg750,00€1mL*10mM (DMSO)88,00€22-(4′-py)-JA
CAS :22-(4′-py)-JA, a semisynthetic derivative of junamycin A isolated from the Thai blue sponge (Xestospongia sp.), exhibits antimetastatic properties by inhibitingFormule :C32H30N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :598.6Kif15-IN-1
CAS :Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Formule :C20H22N4O5SDegré de pureté :99.39% - 99.39%Couleur et forme :SolidMasse moléculaire :430.48TC-Mps1-12
CAS :TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .Formule :C17H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.38GSK215
CAS :GSK215: potent, selective PROTAC degrader of FAK (pDC50=8.4), combines FAK inhibitor VS-4718 and VHL E3 ligase binder, causes fast, lasting FAK degradation.Formule :C50H59F3N10O6SDegré de pureté :99.3%Couleur et forme :SoildMasse moléculaire :985.13Dioleyl phosphatidylserine
CAS :Dioleyl phosphatidylserine is a phospholipid that can activate PKC-γ (Protein Kinase C-gamma) when the Ca2+ concentration is below 0.5 μM, specifically at a concentration of 100 μM.Formule :C42H78NO10PCouleur et forme :SolidMasse moléculaire :788.04Flumatinib mesylate
CAS :Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.Formule :C30H33F3N8O4SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :658.69Ref: TM-T7861
1mg37,00€5mg88,00€10mg133,00€25mg250,00€50mg393,00€100mg628,00€500mg1.301,00€1mL*10mM (DMSO)139,00€NDNA4
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability.Formule :C31H35F3N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :604.68Akt-I-1,2
CAS :Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.Formule :C23H22ClN3Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :375.89Ref: TM-T23695
1mg137,00€2mg180,00€5mg269,00€10mg395,00€25mg615,00€50mg832,00€100mg1.121,00€200mg1.510,00€Hu7691
CAS :Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.Formule :C22H22ClF3N4ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :450.88Decursin
CAS :Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Formule :C19H20O5Degré de pureté :100% - 97.22%Couleur et forme :SolidMasse moléculaire :328.36Ref: TM-T3S1416
1mg43,00€5mg88,00€10mg119,00€25mg259,00€50mg462,00€100mg662,00€500mg1.359,00€1mL*10mM (DMSO)87,00€Daphnetin
CAS :Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14GSK3335103
CAS :GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.Formule :C27H36FN3O4Couleur et forme :SolidMasse moléculaire :485.59K34c hydrochloride
K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.Formule :C38H50ClN5O2Degré de pureté :100% - 99.95%Couleur et forme :SoildMasse moléculaire :644.29Ref: TM-T41151L
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€1mL*10mM (DMSO)887,00€ATN-161 acetate
CAS :ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Formule :C25H39N9O10SDegré de pureté :98.27%Couleur et forme :SoildMasse moléculaire :657.7Ref: TM-T10398L
1mg201,00€5mg497,00€10mg701,00€25mg1.094,00€50mg1.508,00€100mg1.931,00€200mg2.637,00€CZC-8004
CAS :CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.Formule :C17H16FN5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :309.34PF-562271 hydrochloride
CAS :PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.Formule :C21H20F3N7O3SHClDegré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :543.95Vevorisertib
CAS :Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor with inhibitory effects on AKT1/AKT2/AKT3.Formule :C35H38N8ODegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :586.73Delcasertib acetate
Delcasertib acetate is a selective δ protein kinase C (δPKC) inhibitor for the study of acute myocardial infarction and pain.Formule :C122H203N45O36S2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :2940.33Go6976
CAS :Go6976 is a PKC inhibitor, widely used in research to probe PKC functions in health and disease.Formule :C24H18N4ODegré de pureté :95.89%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :378.43Defactinib
CAS :Defactinib (VS-6063) is a second-generation inhibitor of FAK. Defactinib has potential antitumor activity. Cost-effective and quality-assured.Formule :C20H21F3N8O3SDegré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :510.49Protein kinase inhibitor H-7
CAS :H-7: potent PKC inhibitor with 6 μM Ki, also blocks cyclic nucleotide-dependent kinases.Formule :C14H17N3O2SDegré de pureté :99.69%Couleur et forme :SoildMasse moléculaire :291.37Roxifiban acetate
CAS :Roxifiban acetate(DMP 754 acetate) is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used inFormule :C23H33N5O8Degré de pureté :99.33% - 99.56%Couleur et forme :SolidMasse moléculaire :507.54Cyclo(Ala-Arg-Gly-Asp-Mamb)
CAS :Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective antagonist of the RGD peptide with potential applications in pulmonary arterial hypertension research [1].Formule :C23H32N8O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.55Rebastinib
CAS :DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,Formule :C30H28FN7O3Degré de pureté :99.53% - 99.79%Couleur et forme :SolidMasse moléculaire :553.59N-myristoyl-RKRTLRRL
CAS :N-myristoyl-RKRTLRRL is a compound that impedes the binding of protein kinase C (PKC) substrates and inhibits calcium (Ca2+)- and phosphatidylserine (PS)-Formule :C60H117N21O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1308.71Abituzumab
CAS :Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Degré de pureté :>95%Couleur et forme :LiquidChloropyramine hydrochloride
CAS :Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.Formule :C16H20ClN3·HClDegré de pureté :99.45% - 99.8%Couleur et forme :SolidMasse moléculaire :326.26ZMF-23
ZMF-23, a PAK1/HDAC6 dual inhibitor, suppresses PAK1 and HDAC6-mediated aerobic glycolysis and cellular migration while inducing TNF-α-regulated necroptosis andFormule :C22H23Cl2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.36Rottlerin
CAS :Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.Formule :C30H28O8Degré de pureté :97.41% - 99.44%Couleur et forme :Orange To Brown PowderMasse moléculaire :516.54Parbendazole
CAS :Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine.Formule :C13H17N3O2Degré de pureté :99.60%Couleur et forme :Physical Description Crystals Or Fine White Powder (Ntp 1992)Masse moléculaire :247.29GMB-475
CAS :GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.Formule :C43H46F3N7O7SDegré de pureté :100% - 98.78%Couleur et forme :SolidMasse moléculaire :861.93Ref: TM-T8488
1mg96,00€5mg200,00€10mg350,00€25mg590,00€50mg840,00€100mg1.130,00€500mg2.308,00€1mL*10mM (DMSO)274,00€TAT-SAMβA
TAT-SAMβA, an RNAENFDRF (SAMβA) peptide conjugated to the TAT 47-57 protein-derived cell-penetrating peptide, acts as a selective antagonist of the Mfn1-βIIPKCFormule :C118H195N51O31Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2824.13Hexapeptide-10 Acetate
Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.Formule :C30H57N7O10Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :675.81Leukadherin-1
CAS :Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formule :C22H15NO4S2Degré de pureté :98% - 98.49%Couleur et forme :SolidMasse moléculaire :421.49PI3K-IN-48
PI3K-IN-48, a PI3K inhibitor, exhibits an IC50 of 1.55 ± 0.18 μM in A549 cells, demonstrating its potency in this context.Formule :C25H21FN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.44BAY1125976
CAS :BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)Formule :C23H21N5ODegré de pureté :98.87% - ≥98%Couleur et forme :SolidMasse moléculaire :383.45Ref: TM-T7315
1mg39,00€2mg51,00€5mg88,00€10mg137,00€25mg249,00€50mg439,00€100mg647,00€500mg1.359,00€1mL*10mM (DMSO)87,00€Paeoniflorin
CAS :Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.Formule :C23H28O11Degré de pureté :96.9% - 97.16%Couleur et forme :White Fine PowderMasse moléculaire :480.46CpCDPK1/TgCDPK1-IN-1
CAS :CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.Formule :C18H17N5Degré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :303.36Cevipabulin
CAS :Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cellFormule :C18H18ClF5N6ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :464.82S-trityl-L-Cysteine
CAS :S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Formule :C22H21NO2SDegré de pureté :97.02%Couleur et forme :Almost White To Light Yellow Granular PowderMasse moléculaire :363.47Litronesib
CAS :Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.Formule :C23H37N5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.7Plinabulin
CAS :Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).Formule :C19H20N4O2Degré de pureté :100% - 98.69%Couleur et forme :SolidMasse moléculaire :336.39Staurosporine
CAS :Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFormule :C28H26N4O3Degré de pureté :99.24% - 99.98%Couleur et forme :Off-White PowderMasse moléculaire :466.53Ref: TM-T6680
1mg62,00€2mg87,00€5mg97,00€10mg145,00€25mg246,00€50mg401,00€100mg597,00€500mg1.283,00€1mL*10mM (DMSO)109,00€Carbenoxolone disodium
CAS :Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.Formule :C34H48Na2O7Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :614.72Tubulin inhibitor 1
CAS :Tubulin inhibitor 1 blocks tubulin polymerization, with strong anti-tumor effects, induces apoptosis and G2/M mitotic arrest.Formule :C21H24N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.43Eribulin
CAS :Eribulin binds microtubules, halts cancer cell growth, treating metastatic breast cancer.Formule :C40H59NO11Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :729.90Hypocrellin A
CAS :Hypocrellin A is a natural PKC inhibitor with light-induced antitumor, antifungal and antiviral activities.Cost-effective and quality-assured.Formule :C30H26O10Degré de pureté :98% - 99.81%Couleur et forme :SolidMasse moléculaire :546.52Conteltinib
CAS :Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.Formule :C32H45N9O3SDegré de pureté :98.12% - 99.54%Couleur et forme :SolidMasse moléculaire :635.82Ref: TM-T14997
1mg77,00€5mg167,00€10mg240,00€25mg409,00€50mg572,00€100mg800,00€1mL*10mM (DMSO)227,00€Hsp110-STAT3 interaction-IN-2
Hsp110-STAT3 interaction-IN-2 (compound 10b) is an inhibitor of the Hsp110-STAT3 interaction. It is utilized in research related to pulmonary arterial hypertension (PAH).Formule :C24H18F3N5O3Couleur et forme :SolidMasse moléculaire :481.43AKT-IN-25
CAS :AKT-IN-25 (Compound 14a) is an inhibitor of Akt that prevents the phosphorylation of Akt, thereby hindering the PI3K/Akt/mTOR signaling pathway. It arrests the cell cycle at the G1 phase, inhibits the migration of PANC-1 cells, and suppresses the proliferation of cancer cells PANC-1, PATU-T, and SUIT-2, with IC50 values of 3.05, 1.32, and 3.85 μM, respectively.Formule :C14H16N4OCouleur et forme :SolidMasse moléculaire :256.3Tasidotin hydrochloride
CAS :Tasidotin hydrochloride, a dolastatin 15 analog, inhibits microtubule assembly and dynamics.Formule :C32H59ClN6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :643.30CLT-28643
CAS :CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.Formule :C19H17N3O4Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :351.36Dasatinib
CAS :Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formule :C22H26ClN7O2SDegré de pureté :99.59% - 99.86%Couleur et forme :Pale-Yellow SolidMasse moléculaire :488.01DM1-SMe
CAS :DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in human cancer cells.Formule :C36H50ClN3O10S2Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :784.38JB062
CAS :JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiacFormule :C19H17NO4Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :323.34Ref: TM-T67952
1mg185,00€5mg465,00€10mg680,00€25mg1.035,00€50mg1.406,00€100mg1.882,00€500mg3.771,00€1mL*10mM (DMSO)457,00€Gap19
CAS :Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.Formule :C55H96N14O13Degré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :1161.44Verubulin hydrochloride
CAS :Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormule :C17H18ClN3ODegré de pureté :98.29% - 99.77%Couleur et forme :SolidMasse moléculaire :315.8Ref: TM-T13298
5mg50,00€10mg78,00€25mg145,00€50mg210,00€100mg300,00€200mg434,00€1mL*10mM (DMSO)56,00€SAMβA TFA
SAMβA TFA, a selective antagonist of Mfn1-βIIPKC association conjugated to the cell permeable peptide TAT47-57, is a rationally designed inhibitor that improvesFormule :C50H73N17O16·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1168.22 (free acid)Calyxin H
CAS :Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer.Formule :C35H34O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :566.64K-252c
CAS :K-252c is a staurosporine analog isolated from Nocardiopsis sp.Formule :C20H13N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :311.34Drp1 peptide inhibitor P110
CAS :Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused by MPTP. This compound is useful for Alzheimer's disease research. Additionally, Compound P110 reduces mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemia, and myocardial infarction.Formule :C100H179N45O25Couleur et forme :SolidMasse moléculaire :2411.78Albendazole sulfoxide
CAS :Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Formule :C12H15N3O3SDegré de pureté :98.04%Couleur et forme :White To Off-White PowderMasse moléculaire :281.33CCT251455
CAS :CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.Formule :C26H26ClN7O2Degré de pureté :99.1% - 99.1%Couleur et forme :SolidMasse moléculaire :503.98NSC668394
CAS :NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.Formule :C17H12Br2N2O3Degré de pureté :99.29% - 99.29%Couleur et forme :SolidMasse moléculaire :452.1SNX0723
CAS :SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.Formule :C22H26FN3O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :399.46Ref: TM-T28824
1mg89,00€5mg188,00€10mg316,00€25mg512,00€50mg702,00€100mg940,00€500mgÀ demander1mL*10mM (DMSO)207,00€Vedolizumab
CAS :Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.Degré de pureté :SDS-PAGE:98.4%;SEC-HPLC:99.1%Couleur et forme :LiquidMasse moléculaire :146.80 kDa7-Aminocephalosporanic acid
CAS :7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Formule :C10H12N2O5SDegré de pureté :91.05% - 98.22%Couleur et forme :White Solid PowderMasse moléculaire :272.282-Chlorophenoxazine
CAS :2-Chlorophenoxazine is an Akt inhibitor that demonstrates an in vitro inhibitory concentration (IC50) of 2-5 μM and has the capacity to induce apoptosis.Formule :C12H8ClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :217.65PD173955
CAS :PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFormule :C21H16Cl2N4OSDegré de pureté :98.52% - 99.28%Couleur et forme :SolidMasse moléculaire :443.35Olverembatinib
CAS :Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).Formule :C29H27F3N6ODegré de pureté :100% - 99.29%Couleur et forme :SolidMasse moléculaire :532.56Ref: TM-T3071
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg210,00€50mg338,00€100mg535,00€1mL*10mM (DMSO)82,00€Thiocolchicine
CAS :Thiocolchicine inhibits tubulin polymerization (IC50: 2.5 µM, Ki: 0.7 µM), induces apoptosis, and serves as an ADC cytotoxin.Formule :C22H25NO5SDegré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :415.5Kanosamine hydrochloride
CAS :Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species.Formule :C6H14ClNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :215.63Imatinib Mesylate
CAS :Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Formule :C29H31N7O·CH4SO3Degré de pureté :100% - 99.97%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71KG-548
CAS :KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1α, inhibiting lactate production, and can be used in cancer research.Formule :C9H4F6N4Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :282.15Y15
CAS :Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity,Formule :C6H14Cl4N4Degré de pureté :98% - 98%Couleur et forme :Dark Brown CrystalsMasse moléculaire :284.01Ref: TM-T7119
10mg50,00€25mg69,00€50mg82,00€100mg137,00€200mg188,00€500mg331,00€1mL*10mM (DMSO)48,00€Tubulin polymerization-IN-55
CAS :Tubulin polymerisation-IN-55 is a Tubulin Polymerization inhibitor that displays antiproliferative effects on A549, K562, HepG2, MDA-MB-231 and HFL-1.Formule :C22H24N2O4Degré de pureté :98.68%Couleur et forme :SoildMasse moléculaire :380.44T807
CAS :T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).Formule :C16H10FN3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :263.27Ref: TM-T19573
2mg47,00€5mg70,00€10mg107,00€25mg187,00€50mg323,00€100mg550,00€200mg758,00€500mg1.159,00€BCR-ABL-IN-1
CAS :BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.Formule :C23H21F4N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.44MK-2206 free base
CAS :MK-2206 free base is an allosteric Akt inhibitor that is both potent and selective, administered orally, exhibiting IC50 values of 8, 12, and 65 nM for Akt1,Formule :C25H21N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.47ARQ 621
CAS :ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Formule :C28H24Cl2FN5O2Degré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :552.43PKC-θ inhibitor hcl
CAS :PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).Formule :C20H26ClF3N6O3Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :490.91Ref: TM-T5817
1mg93,00€2mg120,00€5mg233,00€10mg376,00€25mg628,00€50mg895,00€100mg1.216,00€500mg2.432,00€KT D606
CAS :KT D606 is a PAK kinase family inhibitor with an IC50 of 4 μM. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.Formule :C59H50N6O10Couleur et forme :SolidMasse moléculaire :1003.06Cyclo(RGDyK)
CAS :Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Formule :C27H41N9O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :619.68Cyclo(-RGDfK) TFA
CAS :Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).Formule :C29H42F3N9O9Degré de pureté :98.99% - 99.54%Couleur et forme :SolidMasse moléculaire :717.69HSP90-IN-23
HSP90-IN-23 (Comp 12-1), a heat shock protein 90 (HSP90) inhibitor, exhibits potent activity with an IC50 of 9nM.Formule :C22H24N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.5FAK activator 1
CAS :ZINC40099027 is a FAK activator that induces gastric mucosal repair in persistent aspirin-associated gastric injury.Formule :C23H26F3N3O3Degré de pureté :98.85%Couleur et forme :SoildMasse moléculaire :449.47Ref: TM-T77665
1mg99,00€5mg229,00€10mg383,00€25mg627,00€50mg1.005,00€100mg1.589,00€200mg2.078,00€1mL*10mM (DMSO)296,00€DN401
CAS :DN401 is a potent TRAP1 and Hsp90 Inhibitor( IC50 = 79 nM for TRAP1, IC50 = 698 nM for Hsp90) with potent anticancer activity.Formule :C13H9BrClN5O2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :382.6Ref: TM-T27193
1mg185,00€5mg409,00€10mg605,00€25mg938,00€50mg1.293,00€100mg1.738,00€500mg3.496,00€1mL*10mM (DMSO)406,00€TRAP1-IN-2
CAS :TRAP1-IN-2, also known as compound 36, is a selective degrader of the TRAP1 client protein that does not affect Hsp90-cytosolic clients.Formule :C46H42F6N2O5P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :878.77Ethoxyquin
CAS :Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.Formule :C14H19NODegré de pureté :95.94%Couleur et forme :Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Masse moléculaire :217.31CWHM-12
CAS :CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).Formule :C26H32BrN5O6Degré de pureté :98.05% - 98.5%Couleur et forme :SolidMasse moléculaire :590.47Ref: TM-TQ0250
1mg40,00€2mg52,00€5mg88,00€10mg126,00€25mg221,00€50mg369,00€100mg550,00€1mL*10mM (DMSO)96,00€Protein Kinase C 19-31 acetate
PKC 19-31 acetate, a serine-altered PKCa-derived PKC inhibitor, tests PKC activity.Formule :C69H122N26O18Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :1603.9NVS-PAK1-1
CAS :NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Formule :C23H25ClF3N5ODegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :479.93Volociximab
CAS :Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.Degré de pureté :95%Couleur et forme :Liquid2119738-71-3
CAS :Compound 2119738-71-3 interacts with the FAK receptor.Formule :C25H29ClFN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.99AD57
CAS :AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.Formule :C22H20F3N7ODegré de pureté :98.23%Couleur et forme :SoildMasse moléculaire :455.44Ref: TM-T22552L
1mg34,00€2mg52,00€5mg116,00€10mg212,00€25mg359,00€50mg512,00€100mg695,00€200mg939,00€1mL*10mM (DMSO)134,00€Fasudil
CAS :Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formule :C14H17N3O2SDegré de pureté :99.79% - 99.84%Couleur et forme :SolidMasse moléculaire :291.37PKCη pseudosubstrate inhibitor,myristoylated
CAS :Myristoylated PKCη pseudosubstrate inhibitor is a cell-permeable compound utilized to investigate the mechanism of action of PKCη [1].Formule :C101H185N41O23SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2373.88Dynamin IN-2
CAS :Dynamin IN-2 (compound 43) is a Wiskostatin analogue.Formule :C22H21ClN2ODegré de pureté :98.81% - 98.83%Couleur et forme :SoildMasse moléculaire :364.87Ref: TM-T64369
1mg140,00€5mg331,00€10mg439,00€25mg667,00€50mg894,00€100mg1.198,00€200mg1.596,00€1mL*10mM (DMSO)341,00€Ifebemtinib hydrochloride
Ifebemtinib (BI-853520) hydrochloride is a potent FAK (focal adhesion kinase) inhibitor with oral bioavailability, exhibiting an IC50 of 1 nM for recombinant FAK. Ifebemtinib hydrochloride demonstrates antiproliferative activity against cancer cells.Formule :C28H29ClF4N6O4Couleur et forme :SolidMasse moléculaire :625.01Ponatinib
CAS :Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56Compound 1T-0219 (SC)
CAS :Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620Formule :C20H19N3O7Degré de pureté :90%Couleur et forme :SolidMasse moléculaire :413.38PF-AKT400
CAS :PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.Formule :C20H22F2N6ODegré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :400.43Ref: TM-T5508
1mg95,00€5mg227,00€10mg325,00€25mg550,00€50mg787,00€100mg1.093,00€1mL*10mM (DMSO)250,00€BIO-1211
CAS :BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).Formule :C36H48N6O9Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :708.8D-ERYTHRO-SPHINGOSINE
CAS :D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activatorFormule :C18H37NO2Degré de pureté :98% - ≥98%Couleur et forme :SolidMasse moléculaire :299.49Arimoclomol
CAS :Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (Formule :C14H20ClN3O3Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :313.78Ref: TM-T13553
1mg115,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)249,00€Taurolithocholic acid sodium salt
CAS :Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFormule :C26H44NNaO5SDegré de pureté :99.79% - 99.93%Couleur et forme :SolidMasse moléculaire :505.69Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Couleur et forme :LiquidMasse moléculaire :145.5 kDaBalamapimod
CAS :Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.Formule :C30H32ClN7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :574.14AG1024
CAS :AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).Formule :C14H13BrN2ODegré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :305.17Tirbanibulin
CAS :Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formule :C26H29N3O3Degré de pureté :99.43% - 99.67%Couleur et forme :SolidMasse moléculaire :431.53Ref: TM-T6345
1mg35,00€5mg66,00€10mg81,00€25mg159,00€50mg280,00€100mg470,00€500mg1.035,00€1mL*10mM (DMSO)70,00€BMS-688521
CAS :BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Formule :C26H19Cl2N5O4Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :536.37Ref: TM-T14676
1mg183,00€5mg464,00€10mg655,00€25mg1.169,00€50mg1.539,00€100mg1.882,00€1mL*10mM (DMSO)547,00€AT-533
CAS :AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and HUVEC activities.Formule :C23H30N4O3Degré de pureté :99.54%Couleur et forme :SoildMasse moléculaire :410.51Ref: TM-T67836
1mg51,00€5mg111,00€10mg170,00€25mg313,00€50mg467,00€100mg672,00€200mg905,00€1mL*10mM (DMSO)117,00€Azelaoyl PAF
CAS :Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.Formule :C33H66NO9PCouleur et forme :SolidMasse moléculaire :651.85BAY1217389
CAS :BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Formule :C27H24F5N5O3Degré de pureté :95.71% - 98.78%Couleur et forme :SolidMasse moléculaire :561.5CIB-L43
CAS :CIB-L43 is an orally active TRBP inhibitor (KD = 4.78 nM) that disrupts the TRBP-dicer interaction (IC50 = 2.34 μM). It suppresses the biosynthesis of oncogenic miR-21, elevates PTEN and Smad7 expression, and inhibits AKT and TGF-β signaling, thereby reducing the proliferation and migration of HCC cells.Formule :C15H16N2O3SCouleur et forme :SolidMasse moléculaire :304.364BCR-ABL-IN-8
CAS :BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].Formule :C30H33N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :571.63Abciximab
CAS :Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:95.9%Couleur et forme :LiquidMasse moléculaire :95.18 kDaVerbascoside
CAS :Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Formule :C29H36O15Degré de pureté :97.46% - 99.55%Couleur et forme :SolidMasse moléculaire :624.59ML-B01
ML-B01 is an orally active inhibitor targeting Akt and PKA, with IC50 values of 2 nM and 136 nM, respectively. It demonstrates good blood-brain barrier (BBB) permeability in mice.Formule :C24H31Cl2N5OCouleur et forme :SolidMasse moléculaire :476.44MSN-125
CAS :MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.Formule :C36H38BrN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :688.61Dihydrocytochalasin B
CAS :Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.Formule :C29H39NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :481.62Ipatasertib
CAS :Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.Formule :C24H32ClN5O2Degré de pureté :98.28% - 99.21%Couleur et forme :SolidMasse moléculaire :458αVβ8-IN-1
CAS :αVβ8-IN-1 is an inhibitor of the αVβ8 integrin. It exhibits growth-suppressive activity against tumors such as EMT6, CT26, KPC, and TKCC-10. αVβ8-IN-1 is suitable for research related to idiopathic pulmonary fibrosis (IPF), nonspecific interstitial pneumonia (NSIP), and various cancers.Formule :C25H32ClN5O4Couleur et forme :SolidMasse moléculaire :502.01FRAX486 HCL(1232030-35-1 free base)
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.Formule :C25H24Cl3FN6ODegré de pureté :98.85% - 99.82%Couleur et forme :SolidMasse moléculaire :549.86Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Couleur et forme :Odour LiquidPF-04929113 Mesylate
CAS :PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Formule :C26H34F3N5O7SDegré de pureté :99% - 99.46%Couleur et forme :SolidMasse moléculaire :617.63Ref: TM-T4342
1mg78,00€2mg100,00€5mg159,00€10mg288,00€25mg419,00€50mg615,00€100mg878,00€500mg1.776,00€1mL*10mM (DMSO)233,00€TCS 21311
CAS :TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.Formule :C27H25F3N4O4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :526.51Bimosiamose
CAS :Bimosiamose has anti-inflammatory effects[1].Formule :C46H54O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :862.91αvβ1 integrin-IN-1
CAS :αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Formule :C26H34N6O6SDegré de pureté :100% - 99.74%Couleur et forme :SolidMasse moléculaire :558.65Ref: TM-T13473
1mg115,00€5mg274,00€10mg432,00€25mg697,00€50mg938,00€100mg1.293,00€200mg1.738,00€1mL*10mM (DMSO)349,00€Cilengitide TFA
CAS :Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formule :C29H41F3N8O9Couleur et forme :SolidMasse moléculaire :702.68DB07107
CAS :DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).Formule :C23H22N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.45Estramustine
CAS :Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.Formule :C23H31Cl2NO3Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :440.4Ref: TM-T20681
5mg47,00€10mg70,00€25mg126,00€50mg202,00€100mg329,00€200mg487,00€1mL*10mM (DMSO)50,00€Lifitegrast sodium
CAS :Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Formule :C29H23Cl2N2NaO7SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :637.46Ro 31-8220 Mesylate
CAS :Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.Formule :C25H23N5O2S·CH4O3SDegré de pureté :98.79% - 99.02%Couleur et forme :SolidMasse moléculaire :553.65Ref: TM-T6643
1mg52,00€2mg67,00€5mg97,00€10mg159,00€25mg244,00€50mg338,00€100mg500,00€1mL*10mM (DMSO)140,00€Blinatumomab
CAS :Blinatumomab (AMG-10,MT-103) is a CD19/CD3 bispecific B-cell and T-cell binding antibody that in acute lymphoblastic leukemia and non-Hodgkin's lymphoma.Couleur et forme :LiquidPironetin
CAS :Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Formule :C19H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.45ALK inhibitor 2
CAS :ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.Formule :C23H28ClN7O3SDegré de pureté :99% - 99.77%Couleur et forme :SolidMasse moléculaire :518.03HS-27
CAS :HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.Formule :C52H60N6O12SDegré de pureté :97.09%Couleur et forme :SolidMasse moléculaire :993.13Ref: TM-T18018
1mg90,00€5mg215,00€10mg344,00€25mg612,00€50mg848,00€100mg1.159,00€1mL*10mM (DMSO)378,00€Chelerythrine chloride
CAS :Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormule :C21H18ClNO4Degré de pureté :95% - 99.19%Couleur et forme :Yellow To Orange SolidMasse moléculaire :383.83Bosutinib hydrate
CAS :Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.Formule :C26H31Cl2N5O4Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :548.46Synstatin (92-119)
CAS :Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 andFormule :C133H207N35O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3032.27GLPG0187
CAS :GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Formule :C29H37N7O5SDegré de pureté :100% - 99.70%Couleur et forme :SolidMasse moléculaire :595.71PAK4-IN-3
PAK4-IN-3 (compound 27e) is a PAK4 inhibitor exhibiting an IC50 of 10 nM and demonstrates antiproliferative effects on A549 cells with an IC50 of 0.61μM.Degré de pureté :98%Couleur et forme :Odour SolidAurothiomalate sodium
CAS :Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.Formule :C4H3AuNa2O4SDegré de pureté :99.66%Couleur et forme :SoildMasse moléculaire :390.07Capivasertib
CAS :Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.Formule :C21H25ClN6O2Degré de pureté :97.59% - 99.6%Couleur et forme :SolidMasse moléculaire :428.92Ref: TM-T1920
1mg40,00€2mg52,00€5mg70,00€10mg99,00€25mg168,00€50mg246,00€100mg378,00€200mg610,00€1mL*10mM (DMSO)89,00€Onalespib
CAS :Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Formule :C24H31N3O3Degré de pureté :98.05% - 99.82%Couleur et forme :SolidMasse moléculaire :409.52Norathyriol
CAS :Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.Formule :C13H8O6Degré de pureté :98.90% - 98.93%Couleur et forme :SolidMasse moléculaire :260.2Ref: TM-TN1990
1mg149,00€5mg354,00€10mg528,00€25mg852,00€50mg1.159,00€100mg1.568,00€1mL*10mM (DMSO)522,00€α7β1 integrin modulator-1
CAS :α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].Formule :C23H29N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :475.56AS2521780
CAS :AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).Formule :C30H41N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.76Dasatinib hydrochloride
CAS :Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).Formule :C22H27Cl2N7O2SDegré de pureté :99.88% - 99.98%Couleur et forme :SolidMasse moléculaire :524.47Pep2m, myristoylated acetate
Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.Formule :C65H122N18O16SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :1443.96PKC 20-28,myristoylated
Myristoylated protein kinase C inhibitor 20-28 (PKC 20-28,myristoylated) is a cell-permeable inhibitor of protein kinase C, utilized in cancer research [1].Formule :C60H106N18O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1255.6CMPD101
CAS :CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formule :C24H21F3N6ODegré de pureté :98.34% - 99.01%Couleur et forme :SolidMasse moléculaire :466.46TPPB
CAS :TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).Formule :C27H30F3N3O3Degré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :501.54DCP-LA
CAS :DCP-LA (FR236924), linoleic acid derivatives, selective and direct activation of PKCε.Formule :C20H36O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.5Abrilumab
CAS :Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Couleur et forme :LiquidEgaptivon pegol
CAS :Egaptivon pegol (ARC1779) is an aptamer that inhibits the interaction of von Willebrand Factor (VWF) with platelet GPIb receptors, exhibiting anti-thromboticDegré de pureté :98%Couleur et forme :LiquidKinesore
CAS :Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Formule :C20H16Br2N4O4Degré de pureté :97.24%Couleur et forme :SolidMasse moléculaire :536.17Ref: TM-T15663
2mg43,00€5mg66,00€10mg94,00€25mg159,00€50mg230,00€100mg346,00€200mg520,00€1mL*10mM (DMSO)74,00€Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.Formule :C19H34N8O11Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :550.52(R)-Fangchinoline
CAS :(R)-Fangchinoline ((+)-Thalrugosine) is extracted from Stephania tetrandra S. Moore.Formule :C37H40N2O6Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :608.72Protein Kinase C (19-31)
CAS :Protein Kinase C (19-31), a PKC inhibitor derived from PKCa, has a serine at position 25 and tests PKC activity.Formule :C67H118N26O16Degré de pureté :98%Couleur et forme :Lyophilized PowderMasse moléculaire :1543.82Mps1-IN-3
CAS :Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formule :C26H31N7O4SDegré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :537.63Ref: TM-T16130
2mg42,00€5mg64,00€10mg92,00€25mg170,00€50mg311,00€100mg449,00€200mg630,00€1mL*10mM (DMSO)74,00€Antitumor agent-86
CAS :Antitumor agent-86 targets MCF-7 cells with 2.62 µM IC50, induces apoptosis, and disrupts RAS/PI3K/Akt/JNK pathways.Formule :C29H31N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.65[Ala107]-MBP (104-118) acetate
[Ala107]-MBP (104-118) acetate ([Ala107]-MBP ) is synthetic peptide analog of bovine myelin basic protein (MBP).Formule :C59H108N20O21Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :1553.72Myosin V-IN-1
CAS :Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.Formule :C29H26N6O3SDegré de pureté :97.31% - 97.31%Couleur et forme :SolidMasse moléculaire :538.62Ref: TM-T72060
1mg314,00€5mg663,00€10mg944,00€25mg1.396,00€50mg1.890,00€100mg2.547,00€1mL*10mM (DMSO)677,00€DPH
CAS :DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.Formule :C18H13FN4O2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :336.32BOS-172722
CAS :BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Formule :C24H30N8ODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :446.55AKT Kinase Inhibitor
CAS :AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.Cost-effective and quality-assured.Formule :C16H19N7O3Degré de pureté :98.53% - 99.86%Couleur et forme :SolidMasse moléculaire :357.37Ref: TM-T10276
1mg136,00€5mg329,00€10mg567,00€25mg887,00€50mg1.188,00€100mg1.605,00€1mL*10mM (DMSO)360,00€CCB02
CAS :CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Formule :C14H9N3ODegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :235.24Ref: TM-T10704
1mg115,00€5mg274,00€10mg432,00€25mg845,00€50mg1.293,00€100mg1.768,00€1mL*10mM (DMSO)303,00€p5 Ligand for Dnak and DnaJ acetate
p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40).Formule :C46H85N15O13SDegré de pureté :96.33%Couleur et forme :SolidMasse moléculaire :1088.32DOTA-cyclo(RGDfK)
CAS :DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.Formule :C43H67N13O14Couleur et forme :SoildMasse moléculaire :990.07Psychosine
CAS :Psychosine (Galactosylsphingosine) is a PKC inhibitor, and is highly cytotoxic, inducing cell death in a variety of cells.Formule :C24H47NO7Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :461.63BI-1950
CAS :BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.Formule :C32H26Cl2FN7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.5KU-177
CAS :KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.Formule :C27H23NO8Degré de pureté :97.34% - 98.54%Couleur et forme :SolidMasse moléculaire :489.47KIF18A-IN-16
CAS :KIF18A-IN-16 (Compound 15) is a polycyclic KIF18A inhibitor. It is applicable in research related to tumors, including colon cancer, breast cancer, and lung cancer.Formule :C30H37N5O4SCouleur et forme :SolidMasse moléculaire :563.71N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS :N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nMFormule :C24H18ClN3ODegré de pureté :98.65%Couleur et forme :SoildMasse moléculaire :399.87Ref: TM-T60041
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)279,00€GNF-7
CAS :GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.Formule :C28H24F3N7O2Degré de pureté :97.05% - 99.47%Couleur et forme :SolidMasse moléculaire :547.53(-)-Indolactam V
CAS :(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.Formule :C17H23N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :301.38ZINC194100678
CAS :ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM.Formule :C10H13N5ODegré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :219.24Tau-aggregation and neuroinflammation-IN-1
CAS :Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.Formule :C25H20N2O7Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :460.44VER49009
CAS :VER49009 (CCT0129397) is an effective HSP90 inhibitor(IC50 =25 nM, Kd=78 nM).Formule :C19H18ClN3O4Degré de pureté :100% - 99.17%Couleur et forme :SolidMasse moléculaire :387.82Ref: TM-T2268
1mg60,00€2mg85,00€5mg111,00€10mg167,00€25mg283,00€50mg472,00€100mg643,00€1mL*10mM (DMSO)96,00€HSDVHK-NH2 acetate
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).Formule :C32H52N12O11Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :780.39Gantofiban
CAS :Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formule :C21H29N5O6Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :447.48FAK inhibitor 7
CAS :FAK inhibitor7, a potent FAK inhibitor, demonstrates an IC50 of 3.58 nM. This compound effectively inhibits downstream signaling cascades of FAK (such as Src and AKT), which leads to cell cycle arrest at the G0/G1 phase and induces cytotoxic autophagy in ovarian cancer cells. Additionally, FAK inhibitor7 has been shown to suppress tumor metastasis and growth in ovarian cancer mouse models.Formule :C32H37N7O3Couleur et forme :SolidMasse moléculaire :567.68ALK-IN-29
ALK-IN-29 (compound 4c) exhibits inhibitory effects on tyrosine protein kinases such as ALK, CDK2/CyclinE1, and FAK, with the strongest inhibition observed against ALK kinase, displaying a 40.63% inhibition rate at a concentration of 10 μM. ALK-IN-29 is applicable in cancer research.Formule :C29H32FN3OCouleur et forme :SolidMasse moléculaire :457.58MPT0B014
CAS :MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.Formule :C19H17NO4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :323.34PF-04691502
CAS :PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formule :C22H27N5O4Degré de pureté :96.27% - ≥95%Couleur et forme :SolidMasse moléculaire :425.48KU-32
CAS :KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.Formule :C20H25NO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.41iRGD peptide
CAS :iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formule :C35H57N13O14S2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :948.04S-methyl DM1
CAS :S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.Formule :C36H50ClN3O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :752.31HSP90-IN-22
CAS :HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM inFormule :C25H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.53
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