Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
Produits appartenant à la catégorie "Signalisation du cytosquelette"
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NU074381b
NU074381b (compound 5b) is an effective inhibitor of S100A4, disrupting the formation of the S100A4-NMII complex with an IC50 value of 0.48 µM. Additionally, it inhibits cell proliferation and migration.Formule :C23H25ClN2O2Couleur et forme :SolidMasse moléculaire :396.91NDNA3
NDNA3 (compound 14) selectively inhibits Hsp90α with an IC50 of 0.51 μM, demonstrating low membrane permeability and minimal toxicity to Ovcar-8 and MCF-10AFormule :C28H32N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.63CMPF
CAS :CMPF is a microtubule protein inhibitor that can be used to study tumors.Formule :C12H16O5Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :240.25HSF1A
CAS :HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.Formule :C21H19N3O2S2Degré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :409.52Ref: TM-T4125
1mg55,00€2mg88,00€5mg139,00€10mg207,00€25mg462,00€50mg677,00€100mg938,00€1mL*10mM (DMSO)130,00€Olverembatinib dimesylate
CAS :Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).Formule :C29H27F3N6O·2CH4O3SDegré de pureté :100% - 99.81%Couleur et forme :SolidMasse moléculaire :724.77Ref: TM-T2429
1mg39,00€2mg51,00€5mg84,00€10mg119,00€25mg229,00€50mg319,00€100mg474,00€1mL*10mM (DMSO)120,00€VnP-16
VnP-16 enhances bone formation by stimulating the differentiation and activity of osteoblasts via direct β1 integrin engagement, which subsequently activatesFormule :C82H112N20O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1649.89BCR-ABL-IN-7
CAS :BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.Formule :C19H16FN3O3SDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :385.41PKCε Inhibitor Peptide acetate
PKCε Inhibitor Peptide acetate is a selective PKCε inhibitor containing the site for its specific receptor for activated C kinase (RACK).Formule :C39H69N9O15Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :904.02Ref: TM-T35827L
1mg65,00€2mg94,00€5mg116,00€10mg187,00€25mg314,00€50mg452,00€100mg620,00€200mg835,00€OSIP-486823
CAS :OSIP-486823(CP248) is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.Formule :C29H28FNO4Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :473.54Valecobulin hydrochloride
CAS :Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.Formule :C26H29ClN6O5SDegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :573.06Ref: TM-T13278
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)207,00€Monastrol
CAS :Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formule :C14H16N2O3SDegré de pureté :98.59% - 99.19%Couleur et forme :SolidMasse moléculaire :292.35Ref: TM-T4048
1mg48,00€5mg78,00€10mg97,00€25mg188,00€50mg311,00€100mg502,00€500mg1.074,00€1mL*10mM (DMSO)87,00€HB-3-20
HB-3-20 induces the degradation of integrin αVβ5 on the cell surface. Transglutaminase 2 (TG2) specifically interacts with HB-3-20, exhibiting a catalytic efficiency (kcat/KM) of 0.16 μM^-1min^-1.Formule :C69H102N20O20Couleur et forme :SolidMasse moléculaire :1531.67Bosutinib
CAS :Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formule :C26H29Cl2N5O3Degré de pureté :98.98% - 99.9%Couleur et forme :Yellowish-Orange Or Pink To Brownish Solid Solid PowderMasse moléculaire :530.45AC 7739
CAS :AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.Formule :C18H22ClNO4Degré de pureté :100% - 99.38%Couleur et forme :SoildMasse moléculaire :351.83Decursinol angelate
CAS :Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.Formule :C19H20O5Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :328.36(S)-Monastrol
CAS :Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formule :C14H16N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.35Nocodazole
CAS :Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32Ref: TM-T2802
5mg37,00€10mg55,00€25mg99,00€50mg168,00€100mg283,00€200mg420,00€500mg682,00€1mL*10mM (DMSO)40,00€R59949
CAS :R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Formule :C28H25F2N3OSDegré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :489.58Ref: TM-T26019
1mg47,00€5mg92,00€10mg145,00€25mg298,00€50mg465,00€100mg702,00€200mg938,00€1mL*10mM (DMSO)96,00€BCR-ABL-IN-10
BCR-ABL-IN-10 (compound B4) is a covalent BCR-ABL inhibitor featuring an arylvinylsulfonate (AVS) moiety, demonstrating an IC50 of 43.1 nM against ABL kinase. It forms a covalent and stable adduct with ABL kinase, enabling the sustained inhibition of intrinsic BCR-ABL activity. This compound is utilized in the study of chronic myeloid leukemia (CML).Formule :C24H22N4O5SCouleur et forme :SolidMasse moléculaire :478.52PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.Formule :C78H132N30O18Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :1778.10
