Hétérocycles azotés (N)

Please enquire for more information about 4-Amino-2-bromopyrimidine-5-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

The drug, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride (CGP 46660), is a competitive antagonist at the human histamine H3 receptor. It has been shown to bind to the histamine H3 receptor in the range of 0.001 to 1 μM and is selective for this receptor over other receptors. CGP 46660 is an optical sensor that can be used in titration calorimetry experiments to measure changes in heat production when it binds to histamine H3 receptors. The drug also has been shown to inhibit guanine nucleotide-binding protein (G protein) signaling pathways and brain functions such as memory formation, learning, and attention span. These effects were demonstrated in humans by measuring EEG activity. The optimum concentration of CGP 46660 for these effects was found to be between 0.01 and 10 μM.

Please enquire for more information about 2-Methyl-3-oxo-3,5,6,7-tetrahydro-2H-cyclopenta[c]pyridine-4-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Chloro-5-ethynylpyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Methyl-2-pyridin-4-yl-ethylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Intermediate for heterocyclic compounds as tyrosine kinase inhibitors and anticancer agents. References McLean, A., et al.: J. Chem. Phys., 72, 5639 (1980), Watts, J., et al.: J. Biol. Chem., 276, 43197 (2001),

a-Tripiperideine is an enolate that can be used as a catalyst to catalyze the formation of carbinols and cyclic compounds. It is also used in the synthesis of trimeric products, such as platelets and erythrocytes. The reaction product of a-tripiperideine with magnesium yields trimerizing agents, which are used in the production of vinylene.

5-Bromo-2-iodopyrimidine is a nitrogen heterocycle that has been found to have potential for use in the treatment of cancer. It is an asymmetric synthesis product of the photophysical reaction, which can be achieved by using an in vivo model. The compound's structure was determined by X-ray crystallography and nuclear magnetic resonance spectroscopy, and it has been shown to have a formyl group with a palladium-catalyzed cross-coupling reaction. 5-Bromo-2-iodopyrimidine can also be used as an acceptor molecule for the potential therapy of cancer. The optical properties of this compound are also noteworthy, with absorption maxima at 330 nm and emission maxima at 385 nm.

Please enquire for more information about (S)-1-Benzyl-2-methylpiperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Phenoxypyrimidin-2-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (2S,5R)-2,5-Dihydro-3,6-dimethoxy-2-[(2S)-2-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-3-methylbutyl]-5-(1-methylethyl)pyrazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Chloro-3,5-difluoropyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page