Hétérocycles azotés (N)

Please enquire for more information about 3-Methoxy-4-[(3-nitropyridin-2-yl)oxy]benzaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Amino-2-bromopyridine is a synthetic compound that has been found to be a potential antitumor agent. It undergoes a palladium-catalyzed coupling reaction with 3-phenylpropene, forming an amide. The reaction yield is dependent on the temperature of the reaction, which must be low enough for the desired product to form. 3-Amino-2-bromopyridine has been shown to possess pharmacokinetic properties and can be transported by amide, hydroxyl, and carboxyl groups. This compound also undergoes acid formation reactions at elevated temperatures.

Please enquire for more information about 6-Chloro-N~4~-cyclopropylpyrimidine-2,4-diamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-{[4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl]thio}propanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2-Benzylbenzimidazole Hydrochloride is an inhibitor of nuclear factor kB activity. References Boggu, P., et al.: Bioorg.Med.Chem, 24, 1872-1878 (2016)

Ropivacaine is a local anaesthetic of the amino ester group that is used to provide relief from pain caused by surgery or other medical procedures. It is a potent inhibitor of the enzyme activity of cholinesterases, which are enzymes responsible for the degradation of acetylcholine. Ropivacaine also inhibits the activity of cardiac Na+/K+ ATPase and Na+-Ca2+ exchanger, thereby reducing the excitability and contractility of heart muscle. This drug has shown pharmacokinetic properties in maternal blood that are similar to those observed in plasma, indicating that it can cross the placenta. Ropivacaine has been shown to have bactericidal effects against bacterial strains such as Escherichia coli and Staphylococcus aureus. In addition, ropivacaine has been shown to inhibit colorectal adenocarcinoma cells in vitro and in vivo. Levobupivacaine

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Phenazopyridine hydrochloride is a drug that is used for the treatment of bladder disorders. It is a chemical compound with a molecular weight of 275. It has been shown to have intramolecular hydrogen bonds and synchronous fluorescence, which are indicative of its chemical stability. The regression analysis data demonstrates that phenazopyridine hydrochloride has anti-infective properties. This drug also has a linear calibration curve in the concentration range of 0.01-1 mg/mL and is used as an anti-inflammatory agent in the treatment of bladder disorders. Phenazopyridine hydrochloride is believed to inhibit bacterial growth by affecting the synthesis of DNA and protein, which are essential for maintaining cellular function.

Please enquire for more information about 2,4-Dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about 1-(2-Thiazolyl)piperazineHydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (S)-Piperidin-3-ylmethanol hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2,4,6-Trimethylpyridine-d11 (CAS# 1219805-54-5) is a useful isotopically labeled research compound.

Please enquire for more information about 7-Piperazin-1-yl-1,3-benzoxazol-2(3H)-one hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Amino-2-chloropyrimidine is a chemical compound that contains the pyrimidine ring. It is a weak base with a conjugative nature, and has substituents on the amino group, which is attached to the 2-position of the pyrimidine ring. The 5-amino group is substituted by chloro and 2-chloro groups. The chemical shift for this molecule ranges from 0 to -5 ppm in dimethyl sulfoxide (DMSO) and benzene. The NH proton appears at 3.2 ppm in DMSO and 4.8 ppm in benzene, while the HN proton appears at 1.8 ppm in DMSO and 2.9 ppm in benzene.

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Applications 2,5-Dimethyl-piperidine is a useful synthetic intermediate in synthesizing chromen-2-ones and chromen-4-ones derivatives. These compounds are inhibitors that act against DNA-PK. References Griffin, R.J., et al.: J. Med. Chem., 48, 569 (2005)

Methyl 4-(2,3,4-trimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylate hydrochloride (MTIC) is a polypeptide that has been shown to have an inhibitory effect on cancer cells. MTIC is a potent inhibitor of the enzyme protein kinase C and can also be used as an adjuvant for immunotherapy. MTIC's mechanism of action is not well understood; however it has been hypothesized that it may act by tethering to the target cell or by binding to endogenous moieties such as proteins and nucleic acids. MTIC has also been shown to inhibit immune cells such as macrophages and T cells.

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Please enquire for more information about tert-Butyl 4-(2,2,2-trifluoroethyl)piperazine-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (3R,4R)-4-Amino-1-oxyl-2,2,6,6-tetramethylpiperidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Imidazo[1,2-a]pyridin-7-amine is a halogen that has been used in the imaging of alpha-synuclein and tritium. It has also been shown to have potential as a drug for Parkinson's disease.

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1-(2-Methoxybenzyl)piperazine (1-MBP) is a multitarget drug that has been shown to have medicinal properties. It inhibits the cholinergic system, which is involved in memory and cognition, as well as pathways such as the inflammatory response and amyloid production. 1-MBP has been shown to inhibit acetylcholinesterase, an enzyme that breaks down acetylcholine, thus increasing the amount of acetylcholine available for signaling. 1-MBP also inhibits cholinesterase, which increases the amount of acetylcholine in the brain. This drug may have synergistic effects with other drugs for Alzheimer's disease, such as donepezil and tacrine. 1-MBP has been used in optimization studies to find new potential treatments for Alzheimer's disease by targeting different aspects of its pathogenesis.

Please enquire for more information about 6-Chloro-N,N'-bis(4-isopropylphenyl)-1,3,5-triazine-2,4-diamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

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