Hétérocycles azotés (N)

Propylpyridiniumbromide is a polymerization catalyst that has an exothermic reaction, increasing the viscosity of a polymer solution. It is used as a coating on paper, textiles, and metal to provide protection from water and chemical substances. Propylpyridiniumbromide binds to the phosphate group in polyphosphate esters and converts them to phosphoric acid. This reaction is thermodynamically favored by the addition of c1-6 alkyl groups, which are added during the polymerization process. The use of propylpyridiniumbromide reduces or eliminates the need for solvents in some reactions due to its ability to act as both a solvent and a catalyst. Reaction products include polypropylene glycols, polyethylene glycols, and polypropylene ethers.

2,5-Dibromopyrimidine (2,5-DBP) is a heterocyclic compound that can be used as an acceptor in cross-coupling reactions. The crystal structures of 2,5-DBP have been determined by X-ray diffraction methods. It also has photocatalytic activity and has been shown to react with 5-HT2C receptors in the brain. This compound is an organometallic compound that contains bromine and nitrogen atoms. 2,5-DBP is soluble in organic solvents such as trifluoroacetic acid and acetonitrile. 2,5-DBP decomposes at temperatures above 150°C to yield water and organic acids. This substance has a magnetic resonance spectroscopy signal at 3 ppm due to the presence of nitrogen atoms.

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2-Acetyl-6-methylpyridine is a compound that belongs to the group of nitrogenous heterocycles. It has been shown to be an inhibitor of protein kinase activity. The inhibition may be due to the steric effects of the acetyl group, which prevents access to the active site. 2-Acetyl-6-methylpyridine has been shown to have growth inhibitory activity in paecilomyces and cocl2 cells by binding with metal ions. This spin resonance study has revealed that 2-acetyl-6-methylpyridine interacts with anions such as chloride or bromide ions by means of hydrogen bonding.

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2-Chloro-3-cyanopyrazine is an efficient method for the synthesis of cholesterol acyltransferase. This molecule has been shown to have tuberculostatic activity, which may be due to its ability to inhibit cholesterol acyltransferase. 2-Chloro-3-cyanopyrazine also has serotonin agonist effects and can be used in the treatment of cancer.

Applications tert-butyl 6-chloropyridazine-3-carboxylate (cas# 1340506-55-9) is a useful research chemical.

Imidazo[1,2-a]pyrimidine is a heterocyclic compound that has been shown to be a potent antimicrobial agent. It has also been shown to have significant cytotoxicity against cervical cancer cells in vitro and can be used as a chemotherapeutic agent for the treatment of cancer. Imidazo[1,2-a]pyrimidine is structurally similar to coumarin derivatives, which are known to be effective against gram-positive bacteria and fungi. This molecule binds to the reactive site of bacterial DNA gyrase and topoisomerase IV and inhibits their function, causing DNA damage. The methylene group on the 2 position of imidazo[1,2-a]pyrimidine is an active methylene group that reacts with halides or alkylthio groups.