Enzymes dans les Protéines Recombinantes

Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Amidase is a hydrolase acting on carbon-nitrogen bonds in linear amides, and can be used in hydrolysis of amides to acids. Amidase 01 is of bacterial origin (P. aeruginosa) and has been produced in E.coli.

Lipoxidase is an enzyme, which is typically sourced from various plant tissues, animals, and some microorganisms. It functions by catalyzing the oxidation of polyunsaturated fatty acids in the presence of oxygen. This enzymatic action results in the formation of lipid hydroperoxides, which are key intermediates in various biochemical pathways, including those involved in cell signaling and the modulation of gene expression. Lipoxidase plays a crucial role in a wide array of biological processes. In plants, it is involved in the metabolism of fatty acids during seed germination and development. In the food industry, its activity is more commonly associated with the development of off-flavors and rancidity in food products rich in unsaturated fats, such as soybeans and peanuts. However, its ability to generate specific lipid oxidation products is also exploited in synthetic chemistry and biotechnological applications, where it assists in the production of certain aldehydes and alcohols used in flavoring agents and fragrances. Additionally, its role in lipid metabolism studies makes it a valuable tool in academic research.

In the ileum, may be involved in defensin processing, including DEFA5.

Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (

NPR1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.

PARP9 Protein, Human, Recombinant (His) is expressed in E.

The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324

Trp A Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27 KDa and the accession number is P0A877.

HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family, and is widely expressed.

Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers, representing an attractive

Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli.

Chlorite dismutase (Cld) found in prokaryotic organisms, also known as Chlorite O2-lyase, is a b-type heme containing enzyme that catalyzes the reduction of

Efficient protease with alanine specificity but only little elastolytic activity.

Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.

PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.

TECR Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system with N-10xHis. The accession number is Q9NZ01.

Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for

Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family.

MTA/SAH nucleosidase Protein, E.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The CalB01 IA lipase has been immobilized on a hydrophobic carrier by adsorption. The immobilized CalB01 lipase has a temperature optimum in the 40 - 50 °C range and pH optimum between pH 5 and 8.

Alterations in GFER gene have been associated with progressive mitochondrial myopathy, congenital cataracts, hearing loss, developmental delay, lactic acidosis

The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription.

FDPS Protein, Mouse, Recombinant (His) is expressed in E.

Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family.

Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family.

Carbonic Anhydrase 9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

CS2 hydrolase (Carbon disulfide hydrolase; E.C. 3.13.1.5) is an enzyme that catalyzes the following reaction:  CS2 + 2 H2O → CO2 + 2 H2S  thus converting carbon disulfide into hydrogen sulfide and carbon dioxide.

Putative phospholipase.

Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.

DNA ligase (ATP) is an enzyme (EC 6.5.1.1) that ligates DNA strands, repairing nicks in double-standed DNA and coupling blunt-ended or cohesive DNA fragments. It requires 3′ hydroxyl and 5′ phosphate nucleoside ends for ligation and ATP as a cofactor.

Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia.

Catalyzes the de novo synthesis of acetyl-CoA in vitro.

Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His) is expressed in E.

GARS Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Carboxymethylenebutenolidase (CMBL), also known as 4-carboxymethylenebut-2-en-4-olide lactonohydrolase, maleylacetate enol- lactonase, dienelactone hydrolase,

CYP2C9 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3

LPAL2 (Lipoprotein(A) Like 2, Pseudogene) is a Pseudogene.

Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily,

Metalloprotease that cleaves substrates preferentially between Phe-Phe residues.

PIP4K2B Protein, Human, Recombinant (His) is expressed in E.

Major role in the synthesis of nucleoside triphosphates other than ATP.

Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.

BoNT/B Protein, Clostridium botulinum, Recombinant (His) is expressed in Yeast.

LacBuster®-L is a novel liquid and ready-to-use sterile beta-lactamase formulation with a broad substrate range against beta-lactam antibiotics including carbapenems, cephalosporins up to 5th generation and penicillins. LacBuster®-L is especially well suited for the direct innoculation method and membrane filtration tests according to US Pharmacopeia (USP <71>) and European Pharmacopeia (EP <2.6.1>). 1 Piece contains 10 vials.

Nitrile hydratase 14 recombinantly expressed in E. coli comes in a freeze-dried formulation. Nitrile hydratases can be utilized to convert nitriles into their corresponding amidese, e.g. to produce acrylamide from acrylonitrile. Additional applications include the removal of nitriles from industrial wastewater. Our nitrile hydratases have been tested for hydrolysis of the following substrates:cyclohexanecarbonitrile, cinnamonitrile, benzonitrile, methacrylonitrile, pivalonitrile.

Fumarate Hydratase (FH) is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate.

Clostridial collagenases are among the most efficient degraders of eukaryotic collagen known; saprophytes use collagen as a carbon source while pathogens

PDE9A Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

HK1 Protein, Human, Recombinant (His) is expressed in E. coli.

Lipase CalA, wildtype, freeze-dried, recombinant, from Candida antarctica is an enzymatic product, which is a highly purified form of lipase enzyme. It is derived from the yeast species Candida antarctica through recombinant DNA technology, ensuring consistency and purity by expressing the enzyme in a controlled microbial system. Lipase CalA functions through a serine hydrolase mechanism, where it catalyzes the hydrolysis of ester bonds in lipids, converting triglycerides into free fatty acids and glycerol. This catalytic activity is highly selective and efficient under mild conditions, making it suitable for various biochemical transformations. The enzyme is widely used in scientific research and industrial applications, including organic synthesis, bioconversion processes, and the production of optically pure compounds. Its stereoselectivity and substrate specificity make it a valuable tool in the synthesis of pharmaceuticals, fine chemicals, and biodiesel production. Additionally, the freeze-dried form ensures long-term stability and facilitates storage and transportation. Researchers often utilize Lipase CalA for applications that require precise enzymatic function and reproducibility in experimental settings.

BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO) is expressed in E.

LSD1 belongs to the flavin monoamine oxidase family.

Anionic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.

KRAS Protein, Human, Recombinant (G12S, GST) is expressed in E. coli expression system with GST tag. The accession number is P01116.

Key enzyme in folate metabolism.

CAMKI Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 41.5 kDa and the accession number is B0YIY3.

GPD2 Protein, Candida albicans, Recombinant (His) is expressed in yeast with C-6xHis tag.

SMARCA2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

IL-1R1 Protein, Rat, Recombinant (His & mFc) is expressed in HEK293 mammalian cells with His, mFc tag.

HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.

Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.

Hydrolytic enzyme; biocatalyst in production of beta-lactam antibiotics

DBT Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

May have a protective function during conditions of oxidative stress.

PRSS23 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli with N-6xHis-SUMO. The accession number is O95084.

CDK5 Protein, Human, Recombinant is expressed in E. coli.

Src Protein, Human, Recombinant (His) is expressed in E. coli.

Mitofusin-2 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system with N-10xHis. The accession number is O95140.

Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family.

Serine / threonine-protein kinase 1, also known as Lymphocyte-oriented kinase, STK1 and LOK, belongs to the protein kinase superfamily, STE Ser / Thr protein

PRKCH Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is P24723.

ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag.

May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.

The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron

cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family.

Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.

Protease enzymes break down proteins and are essential for many biological processes, including digestion, cellular regulation and blood clotting. They are also used in many industrial and biotechnological applications for example in food processing and in detergents.

Reelin Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.9 kDa and the accession number is P78509.

PLA2G10 Protein, Rat, Recombinant (His & Myc) is expressed in E.

Pyruvate kinase (from Rabbit muscle), ammonium sulfate suspension is an enzyme product, which is a purified protein extracted from the muscle tissue of rabbits. This enzyme plays a crucial role in glycolysis, specifically catalyzing the transphosphorylation of phosphoenolpyruvate (PEP) to pyruvate, generating ATP from ADP in the process. This step is a key regulatory point in the glycolytic pathway, which is essential for cellular energy production. The primary mode of action of pyruvate kinase is to facilitate the conversion of PEP to pyruvate by transferring a phosphate group to ADP, yielding ATP. This reaction is crucial for maintaining the flow of carbon intermediates through glycolysis, which ultimately contributes to the cellular ATP pool critical for various physiological processes. Pyruvate kinase from rabbit muscle is widely used in biochemical research to study metabolic pathways and enzyme kinetics. Its applications extend to exploring the regulation of glycolysis, elucidating energy metabolism, and examining allosteric effects and enzyme structure-function relationships. Additionally, this enzyme serves as a model for studying similar enzymes in other organisms, contributing to a broader understanding of metabolic control and energy balance in cells.

HER3/ERBB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

PDE9A Protein, Mouse, Recombinant (His) is expressed in E. coli.

Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation.

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes,

ADAR Protein, Mouse, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q99MU3.

AK3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

o-Glycosidase (O-Glycanase, endo-a-acetylgalactosaminidase, endo-a-N-acetylgalactosaminidase; EC 3.2.1.97) is an enzyme that specifically removes N-acetylgalactosamine disaccharides, that were attached to serine's or threonine's side-chain oxygen (hence o-Glycosidase). One unit of o-Glycosidase will hydrolyze 1.0 mmole of of substrate per minute at 37 °C and pH 5.0.

GSTM5 Protein, Human, Recombinant (His) is expressed in E.

DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of

UDP galactose-4'-epimerase, also known as GALE, enables the body to process a simple sugar called galactose, which is present in small amounts in many foods.

Peptidyl-prolyl cis-trans isomerase E, also known as Cyclophilin E, Cyclophilin-33, Rotamase E, CYP33, PPIE, is an enzyme which belongs to the cyclophilin-type

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-

MPK5 Protein, Japonica rice, Recombinant (His & Myc) is expressed in E.

Coagulation Factor II Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Polymerizes silica around the axial filament during spicule formation.

DXO Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is O77932.

The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324

Sucrose phosphorylase (sucrose glucosyltransferase, disaccharide glucosyltransferase, systemic name Sucrose:orthophosphate α-D-glucosytransferase; EC 2.4.1.7) is an enzyme that catalyzes the following reaction:  sucrose + Pi ⇌ D-fructose + α-D-glucose-1-phosphate  One unit of Sucrose phosphorylase will produce 1.0 μmole of D-fructose per minute in the presence of sucrose and phosphate at pH 7.6 and 25 °C.

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

MMP-13 Protein, Human, Recombinant (His & SUMO) is expressed in E.

Alpha Amylase (Amylase, α-Amylase, 1,4-α-D-glucan glucanohydrolase, glycogenase, PPA; systematic name 4-α-D-glucan glucanohydrolase; EC 3.2.1.1, CAS Number [9000-90-2]) is an enzyme that catalyzes hydrolysis of large polysaccharides into smaller fragments. Alpha amylase targets alpha bonds of 1→4 glycosidic linkages of poly- and oligosaccharides with three or more D-glucose units. One unit of Alpha Amylase will catalyze the hydrolysis of 1.0 μmol of 2-chloro-4-nitrophenyl-α-D-maltotrioside to yield 2-chloro-4-nitrophenol per minute at 37°C. Porcine pancreatic Alpha Amylase is supplied as lyophilized, off-white to white powder, lyophilized from tris chloride and mannitol, pH 7.2. Activity is ≥70U/mL, specific activity ≥100 U/mg protein. Store at -20°C on arrival.

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Lck Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P06239-1.

Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP.

Candidapepsin-2 Protein, Candida albicans (strain WO-1), Recombinant (His) is expressed in E.

GNAQ Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is P50148.

VNN1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

MACROD1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.

Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).

TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway.

Degradation of inorganic polyphosphates (polyP).

Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family.

A proteolytic enzyme synthesized by the HIV cell as part of the GagPol polyprotein

Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-