Enzymes dans les Protéines Recombinantes

Nitrile hydratase 21 recombinantly expressed in E. coli comes in a freeze-dried formulation. Nitrile hydratases can be utilized to convert nitriles into their corresponding amides, e.g. to produce acrylamide from acrylonitrile. Additional applications include the removal of nitriles from industrial wastewater. Our nitrile hydratases have been tested for hydrolysis of the following substrates:cyclohexanecarbonitrile, cinnamonitrile, benzonitrile, methacrylonitrile, pivalonitrile.

Cysteine protease that plays an important role in the inhibition of host innate immune response.

In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during

MBTPS1 Protein, Human, Recombinant (His & SUMO) is expressed in E.

Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between

CKB(Creatine kinase B type) contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain.

Cyclophilin A Protein, Mouse, Recombinant (His) is expressed in E.

N/A.

KRAS Protein, Human, Recombinant (G12D, His) is expressed in E.

Tubulin-folding cofactor B, also known as TBCB, belongs to the TBCB family.

E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

PDK3 Protein, Mouse, Recombinant (His) is expressed in E.

Involved in the maturation of Asn-linked oligosaccharides.

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway.

Ras-related C3 botulinum toxin substrate 2 (Rac2) is a small G-protein belonging to the Ras subfamily of the GTPase family.

Cathepsin C Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is P97821.

Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase.

Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

CSNK2A2 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.4 kDa and the accession number is P19784.

Key enzyme in the cholesterol biosynthesis pathway.

Intercellular signal essential for a variety of patterning events during development.

Protein phosphatase 2C is a key enzyme, which is a serine/threonine-specific phosphatase, derived from various organisms including humans, plants, and bacteria. This enzyme plays a pivotal role in cellular signaling by removing phosphate groups from serine and threonine residues on target proteins, a process known as dephosphorylation. This action is crucial for the regulation of diverse cellular functions, including stress responses, cell division, and apoptosis. Protein phosphatase 2C is widely studied for its involvement in modulating cellular responses to environmental stresses and its role in various signaling pathways. By maintaining the balance between phosphorylation and dephosphorylation, the enzyme ensures proper signal transduction and cellular homeostasis. Researchers extensively investigate its function to understand cellular processes better and to explore therapeutic targets for diseases where signaling pathways are disrupted. Its applications extend to fields such as cancer research, neurobiology, and the study of metabolic disorders, among others. Understanding the intricacies of this enzyme opens doors to potential advancements in therapeutic strategies and the broader comprehension of cellular biology.

PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated

Carbonic Anhydrase 9 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.6 kDa.

PADI2 Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells with C-10xHis. The accession number is Q08642.

Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves.

Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity

YciK Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli.

β-Lactamase-like Protein 2 (LACTB2) is a number of the metallo-beta-lactamase superfamily.LACTB2 also belongs to the Glyoxalase II family.

PML Protein, Human, Recombinant (His) is expressed in E.

GSTM1 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli with N-6xHis. The accession number is P10649.

Urate Oxidase, also known as uricase, catalizes the following reaction: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2.

ST8SIA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

HSD17B13 Protein, Human, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag.

DCP2 Protein, Human, Recombinant (His) is expressed in E.

Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate.

Essential virulence determinant.

Tryptases are Trypsin-like Serine Proteases.

Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions.

Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates.

BACE1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 49 kDa and the accession number is A0A024R3D7.

VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.

Endothelin-converting enzyme 1, also known as ECE-1, is a single-pass type II membrane protein which belongs to thepeptidase M13 family.

Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

DNASE1L3 Protein, Mouse, Recombinant (His) is expressed in E. coli with N-10xHis. The accession number is O55070.

May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition.

Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair.

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the

Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.

P4HB Protein, Cricetulus griseus, Recombinant (His) is expressed in Yeast.

Cathepsin L Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

N/A.

PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E.

tPA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

E3 SUMO protein ligase involved in regulation processes.

Acyl-CoA dehydrogenase Protein, Clostridium acetobutylicum, Recombinant (His & Myc) is expressed in E. coli.

Peroxidases can be utilized as enzymes catalyzing e.g. aromatic ring hydroxylation, epoxidation, halogenation, N- or S-oxidation, ether cleavage and alcohol/aldehyde oxidation reactions. The Peroxidase Kit contains 8 recombinant peroxidases of bacterial and fungal origin with a temperature optimum in the 20-40 °C range and pH optimum between pH 5 and 8.

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Plays a central role as a glucosyl donor in cellular metabolic pathways.

Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins.

CDK7 & CCNH & MNAT1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Beta-amylase activity.

tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that

SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0.

PARP8 Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is Q8N3A8.

Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.

72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs

Phospholipase C Protein, Clostridium perfringens, Recombinant (His) is expressed in E. coli.

CSK Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family.

Serine hydrolase whose substrates have not been identified yet.

Cysteine proteinase with a strong preference for substrates with Lys in the P1 position.

Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate

Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent

Possesses thioredoxin activity.

Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity).

PTPMT1 (PTP localized to the Mitochondrion 1) is a member of the protein tyrosine phosphatase superfamily that is localized exclusively to the mitochondrion.

Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A).

Lipase 08 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 6-8 and temp. optimum at 20-60°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 08 was shown to hydrolyze p-Nitrophenyl esters of butyrate (100 % activity), octanoate (60 %), laurate (7 %), palmitate (0.5 %), stearate (0.2 %), arachidate (0.1 %) and behenate (0.1 %).

Trypsin (EC 3.4.21.4) is a protease that hydrolyses proteins by cleaving the peptide bond at the carboxyl side of the positively charged amino acid (Lysine or Arginine). Trypsin belongs to a family of serine proteases, as it has a serine in its active site. Trypsin can be inhibited by using trypsin inhibitor Alpha 1 Antitrypsin.

Ubiquitin-Conjugating Enzyme E2 J2 (UBE2J2) belongs to the ubiquitin-conjugating enzyme family.

HDAC9 Protein, Human, Recombinant (His) is expressed in E. coli.

IRAK3 Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli.

Renilla-type luciferase Protein, Renilla reniformis, Recombinant (His & Myc & SUMO) is expressed in E.

GAD65 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, is a potent activator of phosphofructokinase, which is a rate-limiting

Flavonol 3-O-rhamnosyltransferase that catalyzes the transfer of rhamnose from UDP-rhamnose to the 3-OH position of kaempferol and quercetin.

Carboxypeptidase E Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

DDX19A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

Presents phospholipase and nuclease activities, depending on the different physiological conditions.

Escherichia coli contains two major aconitases (Acns), AcnA and AcnB.

RRAS2 Protein, Human, Recombinant (GST) is expressed in E. coli.

May activate the peptidyl carrier protein (PCP) domains of fengycin synthase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine

Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, also known as Cam-PDE 1B and PDE1B, is a cytoplasm protein that belongs to the cyclic

Adenylate kinase 1 (EC 2.7.4.3) catalyzes interconversion between ATP, ADP and AMP by catalyzing the following reaction:  ATP + AMP ⇔ 2 ADP  One unit of Adenylate kinase 1 will convert 1.0 µmol ATP and 1.0 µmol AMP to 2.0 µmol ADP per min at optimum conditions.

ART1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

GLA/alpha-Galactosidase A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.

Ag85B Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in yeast with N-6xHis tag.

Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

Protease enzymes break down proteins and are essential for many biological processes, including digestion, cellular regulation and blood clotting. They are also used in many industrial and biotechnological applications for example in food processing and in detergents.

Carbonic Anhydrase 4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family.

Carbonic Anhydrase 10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress.

SAE1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

PLA2G1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

BACE1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

KATNA1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is O75449.

Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone.

Carboxypeptidase M Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Carboxypeptidase A2 (CPA) is a secreted pancreatic procarboxy-peptidase that cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal

D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT