Enzymes dans les Protéines Recombinantes

MMP-8 Protein, Mouse, Recombinant (His) is expressed in CHO mammalian cells with His tag.

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers.

N/A.

CORIN Protein, Human, Recombinant (His) is expressed in E.

Peroxidase 013 belongs to the class of the heme-family peroxidases and can be utilized for catalyzing oxidation/epoxidation of unsaturated C-C bonds, N- or S-oxidation, ether cleavage and alcohol/aldehyde oxidation reactions. The Peroxidase 12 has a temperature optimum in the 20 - 40 °C range and pH optimum between pH 5 and 8.

Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2,

GSTM1 Protein, Mouse, Recombinant (His) is expressed in P. pastoris (Yeast) with N-6xHis. The accession number is P10649.

USP7 Protein, Human, Recombinant (aa 208-560, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

HPN Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.

Degrades casein, gelatins of types I, III, IV, and V, and fibronectin.

ST6GAL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Plays an important role in regulating cell division and growth by reversible phosphorylation signaling.

Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.

Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases.

Flap endonuclease 1/FEN-1 Protein, Human, Recombinant (His & Myc) is expressed in E.

KPC-1 (β-Lactamase) is an enzyme that breaks down β-lactam antibiotics, rendering them ineffective. It originates from strains of bacteria, particularly Klebsiella pneumoniae, which are significant sources of hospital-acquired infections. The mode of action involves hydrolyzing the β-lactam ring found in antibiotics such as penicillins and cephalosporins, neutralizing their antibacterial effects. KPC-1 is primarily used in research settings to study bacterial resistance mechanisms and the development of new antimicrobial strategies. Understanding its structure and function is vital for scientists working to combat antibiotic resistance, a major public health threat. Research involving KPC-1 aids in developing novel inhibitors that can restore the efficacy of β-lactam antibiotics against resistant strains. This enzyme is a critical tool for microbiologists and biochemists investigating the intricate dynamics of drug-resistance.

Luciferase enzyme from Photinus pyralis (firefly), which catalyzes the oxidation of firefly luciferin. This reaction depends on the presence of oxygen and ATP and causes the bioluminescence seen in fireflies

PDXP Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 33.5 kDa and the accession number is P60487.

DLST Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

WalK Protein, S.

TrkA Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

HDAC6 Protein, Human, Recombinant (His) is expressed in E. coli.

MATCAP1 Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is Q68EN5.

KRAS Protein, Human, Recombinant (G12V, His) is expressed in E.

Inositol Polyphosphate 1-Phosphatase (INPP1) is a member of the inositol monophosphatase family.

SOD1 Protein, Danio rerio, Recombinant (His & Myc & SUMO) is expressed in E. coli.

Enolase (phosphopyruvate hydratase, EC 4.2.1.11) is an enzyme that catalyses the following reaction:  2-phospho-D-glycerate ⇌ phosphoenolpyruvate + H2O  One unit of enolase will convert 1.0 μmole of 2-phosphoglycerate to phosphoenolpyruvate per minute.

PA28A, also known as PSME1, is a subunit of proteasome.

gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-

Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene.

HER3/ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

PKM2 Protein, Mouse, Recombinant (E.

TPP1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Porphobilinogen Deaminase (HMBS) is a member of the HMBS family.

ENTPD5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Supplied as lyophilisate containing 1% w/w X-Shining™ Luciferase. The improved, thermostable X-Shining™ Luciferase is suitable for any luciferin-luciferase-based assay using D-luciferin (dLuc) or synthetic pro-luciferins (caged luciferins). Examples of its typical applications include ATP tests in hygiene monitoring, ATP tests in drug screenings and bacteria identification in microbial assays. The termostable luciferase X-Shining™ has been optimised by genetic engineering for strongly increased thermostability and storage stability. In temperature stress tests, the enzyme survives temperatures of 60°C for over an hour, whereas a wild type luciferase from firefly is inactivated after only a few minutes. The extraordinary stability makes it user-friendly and eliminates some of the main disadvantages and limitations of the commonly used wild type luciferase. X-Shining™ Luciferase is supplied as a lyophilisate (1% w/w X-Shining™ Luciferase) or as aqueous solution with glycerol (L-8093), and it may be stored for months at room temperature without significant loss of function. Find out more about our innovative X-Shining range here X-Shining | Innovation | Cymit Quimica Carbosynth.

PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1.

MMP19, also known as RASI-1, is a member of the peptidase M1A family.

A helicase with DNA-dependent ATPase activity.

TDRD12 Protein, Human, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is Q587J7.

Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing

Phosphoenolpyruvate carboxylase is an enzyme, often found naturally in the cytosol of plant cells, which is derived primarily from various plant species. It plays a crucial role in the photosynthetic process, particularly in C4 and CAM plants. By catalyzing the irreversible carboxylation of phosphoenolpyruvate (PEP) to oxaloacetate, this enzyme facilitates the fixation of carbon dioxide, a vital step in the conversion of carbon dioxide into organic compounds during photosynthesis. The enzyme's mode of action involves the catalytic addition of bicarbonate to PEP, resulting in the formation of oxaloacetate and inorganic phosphate. This biochemical transformation is essential for efficient carbon assimilation, supporting the growth and metabolic functions of plants adapted to arid and high-temperature environments. Applications of phosphoenolpyruvate carboxylase are primarily within the realm of plant biology and agricultural research. Studies utilize this enzyme to understand plant responses to environmental stresses and to develop crops with improved photosynthesis efficiency and resilience. Moreover, its role in carbon metabolism provides insights into optimizing crop yield and enhancing carbon sequestration in the context of environmental sustainability.

Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis

Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.

PTPRT Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells with C-hFc. The accession number is O14522.

IVD (Isovaleryl-CoA Dehydrogenase) is a Protein Coding gene.

IAP Protein, Mouse, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is P24822.

ALPK1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.

CBR1 Protein, Human, Recombinant (E.

ACE2/ACEH Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement

Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-

SQLE Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is Q14534.

Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.

N/A.

Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily.

Fructose-1,6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family.

CK2 alpha/CSNK2A1 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family.

Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response.

Human Biliverdin reductase A (BLVRA) is belonged to the Gfo/Idh/MocA family and Biliverdin reductase subfamily.

Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline.

PARP10 Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is Q53GL7.

Granzyme B Protein, Human, Recombinant (E.

Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene.

Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains.

SHH Protein, Human, Recombinant (aa 1-197, His) is expressed in HEK293 mammalian cells with His tag.

75u/mg - Glyceraldehyde 3-phosphate dehydrogenase (GAPDH; EC 1.2.1.12) is an enzyme that catalyzes the following reaction:  glyceraldehyde 3-phosphate + NAD+ + Pi ⇌ glycerate 1,3-bisphosphate + NADH + H+  One unit of GAPDH will convert 1.0 μmole of glyceraldehyde 3-phosphate into glycerate 1,3-bisphosphate per minute at pH 8.5 and 37 °C in the presence of NAD+ and phosphate. NAD+ is available here.

PTPN9 Protein, Mouse, Recombinant is expressed in E. coli with Tag Free. The accession number is O35239.

Peroxidase Protein, Lentinula edodes, Recombinant (His & Myc) is expressed in E. coli.

MMP26 (Matrix Metallopeptidase 26) is a Protein Coding gene.

TrkA Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Asparaginase (EC 3.5.1.1) is an enzyme that catalyzes the following reaction: Asparagine + H2O → Aspartate + NH4+   Industrially, asparaginase is used to reduce the formation of acrylamide in starch-containing food ingredients and products during production processes. Asparaginase has a temperature optimum in the 30 - 50 °C range and pH optimum between pH 8 and 9. One unit will yield 1.0 μmole of ammonia from asparagine per min.

Seems to play an essential role in plague transmission by mediating flea blockage in a temperature-dependent fashion.

CYP26B1 Protein, Human, Recombinant (His) is expressed in E.

CDK7 Protein, Human, Recombinant is expressed in E. coli.

CTRB1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa.

Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family.

Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface.

Mitogen-activated protein kinase kinase kinase kinase 5, also known as Kinase homologous to SPS1/STE2, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, and

Kallikrein 7/KLK7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Transglutaminases (TGase) are a family of calcium-dependent acyl-transfer enzymes ubiquitously expressed in mammalian cells and responsible for catalyzing

Cathepsin E Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine

GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus

Catalyzes an NADPH-dependent reduction of FMN, but is also able to reduce FAD or riboflavin.

Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA.

CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic

ST3GAL4 gene expression is altered in different cancer types, including cervical cancer.

Serine palmitoyltransferase (SPT).

DNase I (Deoxyribonuclease I, EC 3.1.21.1) is an endonuclease that cleaves DNA, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3'. On average it produces tetranucleotides. One unit of the DNase I will increase the absorbance of 260nm light at a rate of 0.001/minute in 1 ml reaction volume at 25°C.

May be involved in cell growth.

BMP-1 Protein, Human, Recombinant (His) is expressed in E.

Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor.

LPL Protein, Mouse, Recombinant (His & Myc) is expressed in E.

Adenosine kinase(ADK) belongs to the family of transferases.

Lipase 13 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 6-8 and temp. optimum at 35-45°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 13 was shown to hydrolyze p-Nitrophenyl esters of butyrate (87 % activity compared to octanoate), octanoate (100 %), palmitate (44 %), stearate (21 %) and arachidate (2 %).

PLA2G1B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.

CRELD2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK).

CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Responsible for the biosynthesis of pyroglutamyl peptides.

PARP6 Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q2NL67.

CECR1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral.

UBA6 (Ubiquitin Like Modifier Activating Enzyme 6) is a Protein Coding gene.

Appears to have a function in striated muscle development and regeneration.

N/A.

PLA2G2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Mer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 54 kDa and the accession number is Q12866.

N/A.