Canal TRP/TRPV
Os canais TRP (Potencial do Receptor Transitório), incluindo a subfamília TRPV, são um grupo de canais iônicos envolvidos em vários processos sensoriais, como sensação de temperatura, percepção da dor e osmorregulação. Os canais TRP são amplamente expressos em diferentes tecidos e desempenham um papel nas respostas fisiológicas aos estímulos ambientais. Os canais TRPV, em particular, estão envolvidos na detecção de mudanças de temperatura e estão implicados em condições como dor crônica, inflamação e câncer. Na CymitQuimica, oferecemos uma gama abrangente de moduladores de canais TRP/TRPV para apoiar sua pesquisa em biologia sensorial, manejo da dor e transdução de sinais.
Produtos da "Canal TRP/TRPV"
Ordenar por
ML204
CAS:ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.Fórmula:C15H18N2Pureza:98.1% - 99.72%Cor e Forma:SolidPeso molecular:226.32Ref: TM-T2298
2mg35,00€5mg50,00€10mg74,00€25mg111,00€50mg145,00€100mg220,00€200mg284,00€500mg467,00€1mL*10mM (DMSO)52,00€ASP7663
CAS:ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.Fórmula:C14H14FNO3Pureza:98.61%Cor e Forma:SolidPeso molecular:263.26GSK3395879
CAS:GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).Fórmula:C20H15F4N3O5SPureza:98%Cor e Forma:SolidPeso molecular:485.41Mesendogen
CAS:Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7Fórmula:C18H16ClF3N2OSPureza:98.90%Cor e Forma:SolidPeso molecular:400.85Apcin A HCL
CAS:Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].Fórmula:C10H15Cl4N5O2Pureza:99.30%Cor e Forma:SolidPeso molecular:379.07Ref: TM-T001
1mgA consultar2mg63,00€5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar200mgA consultar500mg2.792,00€Vanilloid receptor antagonist 1
CAS:Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.Fórmula:C18H15N3O2Pureza:98.14%Cor e Forma:SolidPeso molecular:305.33Ref: TM-T9247
1mg99,00€5mg235,00€10mg354,00€25mg602,00€50mg847,00€100mg1.206,00€1mL*10mM (DMSO)47,00€TRPA1-IN-2
CAS:TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.Fórmula:C24H25F3N4OPureza:98.05%Cor e Forma:SoildPeso molecular:442.48Ref: TM-T77511
1mg85,00€5mg187,00€10mg284,00€25mg482,00€50mg672,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)207,00€FEMA-4809
CAS:FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling agent.Fórmula:C17H17N3O2SPureza:99.19%Cor e Forma:SolidPeso molecular:327.4Ref: TM-T27308
1mg35,00€5mg78,00€10mg116,00€25mg190,00€50mg269,00€100mg383,00€200mg525,00€1mL*10mM (DMSO)88,00€TC-I 2014
CAS:TC-I 2014 shows antiallodynic properties in pain models.Fórmula:C23H19F6N3OPureza:98.75%Cor e Forma:SolidPeso molecular:467.41Ref: TM-T17006
1mg60,00€5mg127,00€10mg202,00€25mg406,00€50mg655,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)133,00€AMG9810
CAS:AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.Fórmula:C21H23NO3Pureza:99.79% - 99.83%Cor e Forma:SolidPeso molecular:337.41JYL 1421
CAS:JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).Fórmula:C20H26FN3O2S2Pureza:98.83%Cor e Forma:SolidPeso molecular:423.57Ref: TM-T15634
1mg70,00€5mg187,00€10mg305,00€25mg612,00€50mg938,00€100mg1.491,00€200mg1.985,00€1mL*10mM (DMSO)173,00€RN-1747
CAS:RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).Fórmula:C17H18ClN3O4SPureza:99.29%Cor e Forma:SolidPeso molecular:395.86Ref: TM-T16763
5mg44,00€10mg74,00€25mg126,00€50mg188,00€100mg316,00€200mg452,00€1mL*10mM (DMSO)47,00€HC067047 Hydrochloride(883031-03-6 free base)
CAS:HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.Fórmula:C26H29ClF3N3O2Pureza:99.95%Cor e Forma:SolidPeso molecular:507.98Ref: TM-T4680L
1mg88,00€5mg172,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)217,00€RN9893
CAS:RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.Fórmula:C21H23F3N4O5SPureza:99.89%Cor e Forma:SolidPeso molecular:500.49D-3263 hydrochloride
CAS:D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.Fórmula:C21H32ClN3O3Pureza:99.85%Cor e Forma:SolidPeso molecular:409.95PF-4840154
CAS:PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception in mice.Fórmula:C26H38N6O2Pureza:98.48%Cor e Forma:SolidPeso molecular:466.62A 425619
CAS:A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonistFórmula:C18H14F3N3OPureza:99.35%Cor e Forma:SolidPeso molecular:345.32Ref: TM-T8562
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)177,00€HC-070
CAS:HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).Fórmula:C22H20Cl2N4O4Pureza:97.06%Cor e Forma:SolidPeso molecular:475.32Ref: TM-T15465
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)168,00€A-967079
CAS:A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectivelyFórmula:C12H14FNOPureza:98.34% - 99.75%Cor e Forma:SolidPeso molecular:207.24Ononetin
CAS:Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).Fórmula:C15H14O4Pureza:98.15%Cor e Forma:SolidPeso molecular:258.27
