Src
Os inibidores de Src são compostos que têm como alvo as quinases da família Src, que estão envolvidas em vários processos celulares, incluindo crescimento, diferenciação e angiogênese. As quinases Src desempenham um papel crucial nas vias de sinalização que promovem a formação de novos vasos sanguíneos em tumores. Ao inibir Src, é possível interromper essas vias, reduzindo assim a angiogênese e o crescimento tumoral. Os inibidores de Src são amplamente utilizados na pesquisa do câncer e no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de Src de alta qualidade para apoiar sua pesquisa em oncologia, sinalização celular e angiogênese.
Produtos da "Src"
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PP 1
CAS:Fórmula:C16H19N5Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:281.36Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Cor e Forma:Pale-Yellow SolidPeso molecular:488.01TL02-59
CAS:TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.Fórmula:C32H34F3N5O4Pureza:95.63%Cor e Forma:SolidPeso molecular:609.64Ref: TM-T13186
1mg71,00€5mg135,00€10mg212,00€25mg359,00€50mg512,00€100mg695,00€200mg937,00€1mL*10mM (DMSO)170,00€Bosutinib
CAS:Fórmula:C26H29Cl2N5O3Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:530.45Dasatinib
CAS:Fórmula:C22H26ClN7O2SPureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:488.01PD173955
CAS:PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFórmula:C21H16Cl2N4OSPureza:98.52% - 99.28%Cor e Forma:SolidPeso molecular:443.35RK-24466
CAS:RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.Fórmula:C23H22N4OPureza:98.07%Cor e Forma:SolidPeso molecular:370.45Ref: TM-T16760
1mg66,00€5mg144,00€10mg227,00€25mg393,00€50mg588,00€100mg905,00€1mL*10mM (DMSO)159,00€Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C27H33N3O6SPureza:99.42%Cor e Forma:SolidPeso molecular:527.63Ref: TM-T15675
2mg38,00€5mg56,00€10mg70,00€25mg126,00€50mg243,00€100mg416,00€200mg562,00€1mL*10mM (DMSO)65,00€Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Fórmula:C28H30N6OSPureza:100% - 99.55%Cor e Forma:SolidPeso molecular:498.64Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFórmula:C29H27F3N6OPureza:98% - 99.60%Cor e Forma:SolidPeso molecular:532.56Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Fórmula:C26H29N3O3Pureza:99.43% - 99.67%Cor e Forma:SolidPeso molecular:431.53Ref: TM-T6345
1mg35,00€5mg66,00€10mg81,00€25mg159,00€50mg280,00€100mg470,00€500mg1.035,00€1mL*10mM (DMSO)70,00€Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Fórmula:C24H23ClFN5O2Pureza:98.37% - 99.86%Cor e Forma:Off-White SolidPeso molecular:467.92Hck-IN-1
CAS:Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.Fórmula:C16H11ClN6O3SPureza:99.07%Cor e Forma:SolidPeso molecular:402.81Ref: TM-T11538
1mg97,00€5mg216,00€10mg344,00€25mg567,00€50mg825,00€100mg1.121,00€200mg1.510,00€1mL*10mM (DMSO)240,00€squarunkinA
CAS:squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-Fórmula:C25H32F3N5O4Pureza:99.29%Cor e Forma:SolidPeso molecular:523.55Anti-Src Antibody (1E789)
Anti-Src Antibody (1E789) is an antibody targeting Src. Anti-Src Antibody (1E789) can be used in ELISA, WB, IF, FCM.Cor e Forma:Odour LiquidAP23846
CAS:AP23846 is an Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines.Fórmula:C24H34N5OPPureza:100%Cor e Forma:SolidPeso molecular:439.53eCF506
CAS:eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)Fórmula:C26H38N8O3Pureza:97.85% - 98.16%Cor e Forma:SolidPeso molecular:510.63β-Hydroxyisovalerylshikonin
CAS:Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumorFórmula:C21H24O7Pureza:98.16%Cor e Forma:SolidPeso molecular:388.41CGP062464
CAS:CGP062464 is an inhibitor of the tyrosine kinase c-Src, with an IC50 of less than 50 nM. It is utilized in research related to osteoporosis and tumor-induced hypercalcemia.Fórmula:C18H14N4Cor e Forma:SolidPeso molecular:286.331Spebrutinib
CAS:Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplasticFórmula:C22H22FN5O3Pureza:100% - 97.02%Cor e Forma:SolidPeso molecular:423.44
