Src
Os inibidores de Src são compostos que têm como alvo as quinases da família Src, que estão envolvidas em vários processos celulares, incluindo crescimento, diferenciação e angiogênese. As quinases Src desempenham um papel crucial nas vias de sinalização que promovem a formação de novos vasos sanguíneos em tumores. Ao inibir Src, é possível interromper essas vias, reduzindo assim a angiogênese e o crescimento tumoral. Os inibidores de Src são amplamente utilizados na pesquisa do câncer e no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de Src de alta qualidade para apoiar sua pesquisa em oncologia, sinalização celular e angiogênese.
Produtos da "Src"
Ordenar por
Hck-IN-2
Hck-IN-2 (Compound 8e) acts as an HCK inhibitor with demonstrated cytotoxic effects on tumor cells. It exhibits an IC50 of 19.58 μM for MDA-MB231 cells and 1.42 μM for MCF-7 cells. Additionally, Hck-IN-2 possesses antitumor activity.Fórmula:C36H35FN6O10Cor e Forma:SolidPeso molecular:730.696KB SRC 4
CAS:KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.CAS 번호13460-73-83-4Fórmula:C32H23ClN8Pureza:99.66% - 99.66%Cor e Forma:SolidPeso molecular:555.03TG 100572 Hydrochloride
CAS:TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.Fórmula:C26H27Cl2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:512.43Saracatinib
CAS:Fórmula:C27H32ClN5O5Pureza:>95.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:542.03Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Fórmula:C36H56O13Pureza:99.37% - 99.66%Cor e Forma:SolidPeso molecular:696.82Ref: TM-T5S1982
1mg35,00€5mg77,00€10mg106,00€25mg170,00€50mg253,00€100mg375,00€500mg892,00€1mL*10mM (DMSO)107,00€MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Cor e Forma:Yellow PowderPeso molecular:193.16XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Fórmula:C22H31N9OPureza:99.07%Cor e Forma:SolidPeso molecular:437.54Ref: TM-T17267
1mg56,00€2mg78,00€5mg99,00€10mg149,00€25mg258,00€50mg393,00€100mg582,00€1mL*10mM (DMSO)110,00€Saracatinib
CAS:Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Fórmula:C27H32ClN5O5Pureza:98% - 99.63%Cor e Forma:SolidPeso molecular:542.03Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Cor e Forma:SolidPeso molecular:938.71ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Fórmula:C21H25N7Pureza:97.63% - ≥95%Cor e Forma:SolidPeso molecular:375.47Ref: TM-T2358
1mg51,00€2mg72,00€5mg105,00€10mg159,00€25mg279,00€50mg462,00€100mg648,00€1mL*10mM (DMSO)116,00€PD-089828
CAS:PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).Fórmula:C18H18Cl2N6OPureza:96.78%Cor e Forma:SolidPeso molecular:405.28Src Inhibitor 3
CAS:Src Inhibitor 3 blocks c-Src kinase (IC50 <3 nM CSK HTRF, <4 nM Caliper), boosting T cell growth from receptor signals.Fórmula:C34H32ClFN8O4Pureza:98.74%Cor e Forma:SolidPeso molecular:671.12Ref: TM-T13000
1mg92,00€5mg187,00€10mg320,00€25mg507,00€50mg702,00€100mgA consultar1mL*10mM (DMSO)279,00€PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Fórmula:C17H17N7Pureza:99.19% - 99.67%Cor e Forma:SolidPeso molecular:319.36Tirbanibulin dihydrochloride
CAS:Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C26H31Cl2N3O3Pureza:98%Cor e Forma:SolidPeso molecular:504.45Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Fórmula:C29H34N6O4S2Pureza:100% - 97.67%Cor e Forma:SolidPeso molecular:594.75Ref: TM-T8544
5mg35,00€10mg51,00€25mg77,00€50mg95,00€100mg144,00€200mg225,00€500mg373,00€1mL*10mM (DMSO)49,00€PI3K-IN-1
CAS:PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.Fórmula:C31H29N5O6SPureza:97.03% - 98%Cor e Forma:SolidPeso molecular:599.667-Hydroxy-4H-chromen-4-one
CAS:7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).Fórmula:C9H6O3Pureza:97.65%Cor e Forma:SolidPeso molecular:162.14AD80
CAS:AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.Fórmula:C22H19F4N7OPureza:100% - 99.49%Cor e Forma:SolidPeso molecular:473.43Ref: TM-T4301
1mg47,00€5mg92,00€10mg145,00€25mg283,00€50mg464,00€100mg680,00€500mg1.406,00€1mL*10mM (DMSO)96,00€PP1
CAS:PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Fórmula:C16H19N5Pureza:99% - 99.97%Cor e Forma:Off-White To Grey SolidPeso molecular:281.36Ref: TM-T6196
1mg40,00€2mg52,00€5mg88,00€10mg118,00€25mg202,00€50mg283,00€100mg444,00€500mg998,00€1mL*10mM (DMSO)94,00€1-Naphthyl PP1
CAS:Fórmula:C19H19N5Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:317.40
