Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Produtos da "Receptor de Canabinóides"
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GFB-024
GFB-024 is a humanized antibody targeting CB1, which can be used to study obesity.Cor e Forma:LiquidPeso molecular:145.5yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Fórmula:C15H14O4Pureza:98.82% - 99.55%Cor e Forma:Pale Yellow PowderPeso molecular:258.27Ref: TM-T3S0738
1mg70,00€5mg135,00€10mg207,00€25mg349,00€50mg515,00€100mg735,00€1mL*10mM (DMSO)177,00€Cannabidivarinic acid
CAS:Cannabidivarinic acid (CBDVA), the carboxylic acid precursor to cannabidivarin (CBDV), is a non-psychoactive cannabinoid found in Cannabis and known for its anti-inflammatory properties.Fórmula:C20H26O4Cor e Forma:SolidPeso molecular:330.42Amauromine
CAS:Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a novel alkaloid with vasodilatory activity.Fórmula:C32H36N4O2Cor e Forma:SolidPeso molecular:508.651'-Naphthoyl-2-methylindole
CAS:1'-Naphthoyl-2-methylindole (Compound 88) acts as a cannabinoid mimic and an inhibitor of Win 55212-2, displaying a 34% inhibition of [3H]Win 55212-2 binding to cannabinoid receptors at a concentration of 3 μM.Fórmula:C20H15NOCor e Forma:SolidPeso molecular:285.34CB1/2 receptor-1
CAS:CB1/2 receptor-1 (compound 5.3) serves as an agonist for CB1/2 receptors and is utilized in angiogenesis research.Fórmula:C33H48O2Cor e Forma:SolidPeso molecular:476.73Bzo-poxizid
CAS:Bzo-poxizid is a synthetic cannabinoid and a psychoactive substance.Fórmula:C20H21N3O2Cor e Forma:SolidPeso molecular:335.40(±)-9-Nor-9α-hydroxy Hexahydrocannabinol
CAS:(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-structured compound that exhibits potent cannabinoid-like activity in both dogs and mice.Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.45Virodhamine
CAS:Virodhamine (O-arachidonoyl ethanolamine), an endocannabinoid, is an antagonist of CB1 receptor and an agonist of CB2 receptor.Fórmula:C22H37NO2Pureza:98%Cor e Forma:SoildPeso molecular:347.53Voacamine
CAS:Voacamine: an indole alkaloid, CB1 antagonist, inhibits P-gp, may affect rhythm.Fórmula:C43H52N4O5Pureza:98.54%Cor e Forma:SolidPeso molecular:704.9Palmitoyl serinol
CAS:Anticancer agent 110 is an anticancer compound with cytotoxic, antitumor and antileukemic activities.Fórmula:C19H39NO3Cor e Forma:SolidPeso molecular:329.52CB-25
CAS:CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cellsFórmula:C25H41NO3Pureza:98%Cor e Forma:SolidPeso molecular:403.6GW842166X
CAS:GW842166X: Potent CB2 agonist, EC50=63 nM, inactive at CB1, in Phase 2 trials.Fórmula:C18H17Cl2F3N4O2Pureza:99.47%Cor e Forma:SolidPeso molecular:449.25Ref: TM-T6527
1mg35,00€2mg50,00€5mg77,00€10mg123,00€25mg224,00€50mg330,00€100mg492,00€1mL*10mM (DMSO)74,00€Org 27569
CAS:Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity andFórmula:C24H28ClN3OPureza:100% - ≥95%Cor e Forma:SolidPeso molecular:409.95N-Oleoyl glycine
CAS:N-Oleoyl glycine, a lipoamino acid, was able to promote 3T3-L1 adipogenesis through the activation of CB1 receptor and the enhancement of insulin-mediated AktFórmula:C20H37NO3Pureza:99.92%Cor e Forma:SolidPeso molecular:339.512,3-Butanediol
CAS:2,3-Butanediol is a butanediol derived from the bioconversion of natural resources which has great potential for diverse industries, including chemical,Fórmula:C4H10O2Pureza:98.64%Cor e Forma:Nearly Colorless Crystalline Solid Or Liquid SolidPeso molecular:90.12O-1269
CAS:O-1269 acts as a partial agonist for the cannabinoid receptor 1 (CB1R), with a binding affinity (Ki) of 32 nM. Additionally, it exhibits analgesic properties.Fórmula:C22H22Cl3N3OCor e Forma:SolidPeso molecular:450.79AB-FUBINACA 3-fluorobenzyl isomer
CAS:AB-FUBINACA 3-fluorobenzyl isomer is a synthetic cannabinoid and an indazole derivative, exhibiting high affinity for central CB1 receptors (Ki= 0.9 nM) and possessing anticonvulsant activity.Fórmula:C20H21FN4O2Cor e Forma:SolidPeso molecular:368.41AM-1235
CAS:AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.Fórmula:C24H21FN2O3Pureza:99%Cor e Forma:SolidPeso molecular:404.43CB 65
CAS:CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.Fórmula:C22H28ClN3O3Pureza:98.39%Cor e Forma:SolidPeso molecular:417.93
