Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Produtos da "Sinalização Citoesquelética"
Ordenar por
Meclofenamic acid
CAS:Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.Fórmula:C14H11Cl2NO2Pureza:98%Cor e Forma:SolidPeso molecular:296.15Tubulin polymerization-IN-47
CAS:Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancerFórmula:C22H21N3O3Pureza:99.69%Cor e Forma:SoildPeso molecular:375.42Adhibin
Adhibin is an allosteric inhibitor of RhoGAP class IX myosin (RhoGAP class IXmyosin), effectively inhibiting Myo9 ATPase in both mammals and invertebrates with an IC50 of 2.5 µM and 2.6 µM, respectively. It binds to ATPase, disrupting myosin's motor functions, blocking RhoGTPase-related signaling pathways, and affecting cellular migration, adhesion, and division. Adhibin is applicable for research in cancer metastasis.Fórmula:C13H9Br2NOCor e Forma:SolidPeso molecular:355.02Terflavoxate
CAS:Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine.Fórmula:C26H29NO4Pureza:98.07%Cor e Forma:SolidPeso molecular:419.51Meclofenamic acid sodium
CAS:Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.Fórmula:C14H10Cl2NNaO2Pureza:98% - 98.96%Cor e Forma:SolidPeso molecular:318.14PKCα (C2-4) inhibitor peptide
PKCα (C2-4) inhibitor peptide is a specific antagonist to PKCα that impedes the α1A-adrenoreceptor agonist A-61603 [1] from inhibiting I_Kr.Fórmula:C47H74N14O17Pureza:98%Cor e Forma:SolidPeso molecular:1107.17TAT-Gap19 acetate
TAT-Gap19 acetate, a Cx43 HC inhibitor, crosses blood-brain barrier, reduces liver fibrosis in mice, and spares Cx43 GJCs.Fórmula:C119H212N46O26Pureza:99.74%Cor e Forma:SolidPeso molecular:2703.25Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Fórmula:C16H18N2O2SPureza:98.07%Cor e Forma:SolidPeso molecular:302.39Ref: TM-T3118
1mg35,00€2mg48,00€5mg62,00€10mg87,00€25mg156,00€50mg235,00€100mg354,00€1mL*10mM (DMSO)67,00€MKLP2-IN-1
CAS:MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.Fórmula:C23H19BrFN3O2Cor e Forma:SolidPeso molecular:468.318M2698
CAS:M2698 (MSC2363318A) is an inhibitor of p70S6K, Akt1 and Akt3 with IC50s of 1 nM. M2698 shows anti-cancer activity.Fórmula:C21H19ClF3N5OPureza:99.36%Cor e Forma:SolidPeso molecular:449.86Ref: TM-T11928
1mg50,00€5mg105,00€10mg170,00€25mg329,00€50mg475,00€100mg655,00€200mg883,00€1mL*10mM (DMSO)123,00€JB061
JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscleFórmula:C19H17NO4Pureza:98.76%Cor e Forma:SoildPeso molecular:323.34Ref: TM-T67951
1mg39,00€5mg84,00€10mg114,00€25mg202,00€50mg304,00€100mg452,00€500mg938,00€1mL*10mM (DMSO)92,00€KTC1101
CAS:KTC1101 is a pan-PI3K inhibitor with antiproliferative and anticancer activities, reducing phosphorylation of downstream AKT and mTOR.Fórmula:C21H26F2N8O3Pureza:98.75%Cor e Forma:SoildPeso molecular:476.48Ref: TM-T89831
1mg80,00€5mg158,00€10mg248,00€25mg495,00€50mg800,00€100mg1.283,00€1mL*10mM (DMSO)158,00€BJE6-106
CAS:BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM).Fórmula:C26H23NO2Cor e Forma:SolidPeso molecular:381.47RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Fórmula:C24H19Cl3N2O4Pureza:98.55%Cor e Forma:SolidPeso molecular:505.78Danegaptide Hydrochloride
CAS:Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) (GAP-134 Hydrochloride) is a selective modifier of the gap junction protein.Fórmula:C14H18ClN3O4Pureza:99.55%Cor e Forma:SolidPeso molecular:327.76Rifabutin
CAS:Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.Fórmula:C46H62N4O11Pureza:99.27% - 99.8%Cor e Forma:Red-Violet Crystalline PowderPeso molecular:847GNF-5
CAS:GNF-5, non-ATP Bcr-Abl inhibitor (IC50: 0.22±0.1 uM, wild-type), improves upon GNF-2 with better pharmacokinetics.Fórmula:C20H17F3N4O3Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:418.37CK-636
CAS:CK-636 (CK-0944636), an Arp2/3 complex inhibitor, can inhibit actin polymerization induced by the human, fission yeast and bovine Arp2/3 complex.Fórmula:C16H16N2OSPureza:98.10% - 98.88%Cor e Forma:SolidPeso molecular:284.38Gap 27
CAS:Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.Fórmula:C60H101N15O17Pureza:100%Cor e Forma:SolidPeso molecular:1304.53
