Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Produtos da "Sinalização Citoesquelética"
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Pivanex
CAS:Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.Fórmula:C10H18O4Pureza:≥98%Cor e Forma:SolidPeso molecular:202.25MMAD
CAS:MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).Fórmula:C41H66N6O6SPureza:99.25% - 99.91%Cor e Forma:SolidPeso molecular:771.06Tasiamide B
CAS:Tasiamide B is a linear peptide and Cathepsin D inhibitor discovered in the marine cyanobacterium Symploca sp. This compound serves as an excellent template for the development of aspartic protease inhibitors. Tasiamide B effectively targets skin cancer through its strong interaction with the protein HSP90.Fórmula:C50H74N8O12Cor e Forma:SolidPeso molecular:979.17Crolibulin
CAS:Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.Fórmula:C18H17BrN4O3Pureza:98.19%Cor e Forma:SolidPeso molecular:417.26Ref: TM-T15012
1mg64,00€2mg92,00€5mg137,00€10mg216,00€25mg376,00€50mg562,00€100mg753,00€1mL*10mM (DMSO)150,00€LXW7 TFA (1313004-77-1 free base)
LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an anti-inflammatory effect.Fórmula:C31H49F3N12O14S2Pureza:98%Cor e Forma:SolidPeso molecular:934.92GSK 3008348 hydrochloride
CAS:GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.Fórmula:C29H37N5O2xHClPureza:99.54%Cor e Forma:SolidPeso molecular:0Cyclo(RGDyK) trifluoroacetate
CAS:Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Fórmula:C31H43F6N9O12Pureza:≥95%Cor e Forma:SolidPeso molecular:847.72SS28
CAS:SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.Fórmula:C18H20O3Pureza:98%Cor e Forma:SolidPeso molecular:284.35AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Fórmula:C26H30F3N7O2Pureza:98.17% - 99.56%Cor e Forma:SolidPeso molecular:529.56Ref: TM-T4053
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg187,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)92,00€Eg5-IN-1
Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an IC50 value of 1.97 µM for Eg5.Eg5-IN-1 can be used in cancer research.Fórmula:C23H16ClFN4OPureza:98.21%Cor e Forma:SolidPeso molecular:418.85PKCTheta-IN-2
CAS:PKCTheta-IN-2 (compound 14) is a potent and selective inhibitor of PKCθ, with an IC50 value of 0.25 nM. It demonstrates good selectivity across a broad range of kinases, including the PKC subfamily (30 kinases). Additionally, PKCTheta-IN-2 effectively inhibits the production of IL-2 in mice, where it exhibits an IC50 of 682 nM.Fórmula:C24H23N5O2Cor e Forma:SolidPeso molecular:413.47Sabeluzole
CAS:Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.Fórmula:C22H26FN3O2SPureza:99.91%Cor e Forma:SolidPeso molecular:415.52Zagotenemab
CAS:Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Pureza:95% - > 95%Cor e Forma:LiquidPeso molecular:145.3 kDaNilotinib
CAS:Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.Fórmula:C28H22F3N7OPureza:99.61% - 99.83%Cor e Forma:Off-White SolidPeso molecular:529.52PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Fórmula:C21H22N6OPureza:98.82%Cor e Forma:SolidPeso molecular:374.44Ref: TM-T8764
1mg113,00€2mg160,00€5mg230,00€10mg369,00€25mg615,00€50mg879,00€100mg1.198,00€500mg2.395,00€1mL*10mM (DMSO)240,00€gp96-II
Gp96-II is a gp96-blocking peptide that antagonizes cytokine production induced by gp96-mediated LPS. This compound is useful for research into inflammatory diseases.Fórmula:C200H353N59O53SCor e Forma:SolidPeso molecular:4464.37ZINC00640089
CAS:ZINC00640089: Selective LCN2 inhibitor; curbs SUM149 cell growth and AKT activity; useful for IBC research.Fórmula:C20H13F3N2O2Pureza:98.13% - 99.27%Cor e Forma:SolidPeso molecular:370.32AMP-PCP
CAS:AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.Fórmula:C11H18N5O12P3Pureza:98%Cor e Forma:SolidPeso molecular:505.21Aurothiomalate tetramer sodium
Aurothiomalate tetramer sodium, a tetrameric form of Aurothiomalate sodium, functions as an anti-arthritis gold agent. It also acts as a potent and selective inhibitor of the oncogenic PKCι signaling pathway.Cor e Forma:Odour Solid2-Methoxyhydroquinone
CAS:2-Methoxyhydroquinone is a phenolic compound that reduces the production of TNF-α-induced chemokine (C-C motif) ligand 2 (CCL2) with an IC50 value of 64.3 µM. It also serves as a synthetic precursor to the Hsp90 inhibitor Geldanamycin.Fórmula:C7H8O3Cor e Forma:SolidPeso molecular:140.14
