Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Produtos da "Sinalização Citoesquelética"
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Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
CAS:Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and a synthetic α5β1 integrin ligand.Fórmula:C22H35N9O9Pureza:98%Cor e Forma:SolidPeso molecular:569.57PF-06651481-00
CAS:PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.Fórmula:C26H29Cl2N5O3Pureza:97.57%Cor e Forma:SolidPeso molecular:530.45SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Fórmula:C15H14ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:319.81PLN-1474
CAS:PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.Fórmula:C24H37N3O4Pureza:99.25%Cor e Forma:SoildPeso molecular:431.57Ref: TM-T60101
1mg52,00€5mg111,00€10mg180,00€25mg305,00€50mg439,00€100mg612,00€1mL*10mM (DMSO)124,00€Cercosporin
CAS:Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).Fórmula:C29H26O10Pureza:98%Cor e Forma:SolidPeso molecular:534.51N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Fórmula:C28H29N7OPureza:98.60%Cor e Forma:Off-White To Pale-Yellow SolidPeso molecular:479.58Ref: TM-T11641
1mg92,00€5mg170,00€10mg319,00€25mg540,00€50mg777,00€100mg1.074,00€1mL*10mM (DMSO)178,00€Geldanamycin
CAS:Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.Fórmula:C29H40N2O9Pureza:98.83% - 99.27%Cor e Forma:Yellow To Orange PowderPeso molecular:560.64MAP4343
CAS:Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.Fórmula:C22H34O2Pureza:99.32%Cor e Forma:SolidPeso molecular:330.5E7820
CAS:E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Cor e Forma:SolidPeso molecular:336.37Ref: TM-T4435
1mg35,00€2mg52,00€5mg69,00€10mg88,00€25mg144,00€50mg210,00€100mg339,00€200mg502,00€1mL*10mM (DMSO)85,00€Iso-H7 dihydrochloride
CAS:Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Fórmula:C14H19Cl2N3O2SPureza:99.64%Cor e Forma:White Crystalline SolidPeso molecular:364.29Ref: TM-T7501
2mg40,00€5mg52,00€10mg90,00€25mg138,00€50mg197,00€100mg293,00€200mg408,00€1mL*10mM (DMSO)66,00€FAK-IN-21
CAS:FAK-IN-21 (compound 9) is a FAK inhibitor with an IC50 value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.Fórmula:C22H22F2N8O3SCor e Forma:SolidPeso molecular:516.52KIF18A-IN-2
CAS:KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.Fórmula:C25H34N4O5S2Pureza:99.05%Cor e Forma:SolidPeso molecular:534.69Ref: TM-T60026
1mg74,00€5mg172,00€10mg245,00€25mg383,00€50mg507,00€100mg672,00€200mg910,00€1mL*10mM (DMSO)202,00€HSP70-IN-1
CAS:HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).Fórmula:C24H28N6O2SPureza:100%Cor e Forma:SolidPeso molecular:464.58Ref: TM-T3487
1mg96,00€5mg227,00€10mg354,00€25mg620,00€50mg847,00€100mg1.169,00€1mL*10mM (DMSO)230,00€ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Fórmula:C18H17N3O4SPureza:98.84% - 99.50%Cor e Forma:SolidPeso molecular:371.41AKE-72
CAS:AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.Fórmula:C30H29F3N6OPureza:98.3%Cor e Forma:SoildPeso molecular:546.59Radotinib
CAS:Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notablyFórmula:C27H21F3N8OPureza:99.13% - 99.97%Cor e Forma:SolidPeso molecular:530.5Col003
CAS:Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Fórmula:C14H11NO4Pureza:98.67% - 99.03%Cor e Forma:SolidPeso molecular:257.24Ref: TM-T10860
2mg47,00€5mg70,00€10mg107,00€25mg216,00€50mg350,00€100mg542,00€200mg778,00€500mg1.169,00€1mL*10mM (DMSO)70,00€CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Fórmula:C18H18ClN5OPureza:99.81%Cor e Forma:SolidPeso molecular:355.82Ref: TM-T14943
1mg35,00€2mg48,00€5mg74,00€10mg97,00€25mg187,00€50mg331,00€100mg547,00€1mL*10mM (DMSO)82,00€D-64131
CAS:D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.Fórmula:C16H13NO2Pureza:99.48% - 99.67%Cor e Forma:SolidPeso molecular:251.28PKCε (85-92)
CAS:PKCε (85-92) is a biologically active peptide that functions as a specific activator of ε-PKC and induces MARCKS phosphorylation in wild-type cells, but doesFórmula:C39H54N10O14Pureza:98%Cor e Forma:SolidPeso molecular:886.9
