Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Produtos da "Sinalização Citoesquelética"
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Myoseverin
CAS:Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.Fórmula:C24H28N6O2Pureza:99.25%Cor e Forma:SolidPeso molecular:432.52Ref: TM-T21632
5mg35,00€10mg52,00€25mg101,00€50mg170,00€100mg255,00€200mg374,00€1mL*10mM (DMSO)38,00€Etaracizumab
CAS:Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.Pureza:>95% - >95%Cor e Forma:LiquidPeso molecular:144.3 (kDa)Carotegrast methyl
CAS:Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Fórmula:C28H26Cl2N4O5Pureza:99.40%Cor e Forma:SolidPeso molecular:569.44Ref: TM-T30751
10g9.508,00€1mg74,00€5mg160,00€10mg264,00€25mg528,00€50mg785,00€100mg1.130,00€200mg1.549,00€1mL*10mM (DMSO)170,00€AZ3146
CAS:AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.Fórmula:C24H32N6O3Pureza:100% - 97.84%Cor e Forma:SolidPeso molecular:452.55GNF-2
CAS:GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.Fórmula:C18H13F3N4O2Pureza:98.17% - ≥95%Cor e Forma:SolidPeso molecular:374.32αvβ6 integrin inhibitor 2
CAS:αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.Fórmula:C21H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:386.49Corosolic acid
CAS:Corosolic acid inhibits angiogenesis, suppresses FAK, fights various cancers, induces apoptosis, and degrades β-catenin.Fórmula:C30H48O4Pureza:99.46% - 99.88%Cor e Forma:Fine-Brown Yellow PowderPeso molecular:472.7Hsp90-IN-38
CAS:Hsp90-IN-38 (compound 20m) is an inhibitor of HSP90 (heat shock protein). It demonstrates a strong binding affinity to HSP90 with a Kd of 87 nM. The compound inhibits ATPase activity with an IC50 of 0.13 μM. Hsp90-IN-38 also shows inhibitory effects on HCT116, MCF-7, SKBr3, K562, and A549 cells with IC50 values of 0.187, 0.072, 0.105, 0.403, and 0.031 μM, respectively.Fórmula:C28H35N3O5Cor e Forma:SolidPeso molecular:493.595OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Fórmula:C30H30F3N5OPureza:98.03%Cor e Forma:SolidPeso molecular:533.59Ref: TM-T5485
1mg97,00€2mg144,00€5mg235,00€10mg378,00€25mg647,00€50mg920,00€100mg1.225,00€500mg2.498,00€1mL*10mM (DMSO)306,00€Aβ-IN-1 TFA
Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.Fórmula:C37H50F3NO2Pureza:100%Cor e Forma:SoildPeso molecular:597.79SNX2112
CAS:SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.Fórmula:C23H27F3N4O3Pureza:98.9% - 99.46%Cor e Forma:SolidPeso molecular:464.48Ref: TM-T6305
1mg40,00€5mg85,00€10mg127,00€25mg220,00€50mg334,00€100mg477,00€200mg662,00€1mL*10mM (DMSO)87,00€CCT251236
CAS:CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.Fórmula:C32H32N4O5Pureza:98.82% - 99.89%Cor e Forma:SolidPeso molecular:552.62Ref: TM-T14905
1mg39,00€5mg116,00€10mg221,00€25mg457,00€50mg733,00€100mg1.111,00€200mg1.501,00€1mL*10mM (DMSO)144,00€Protein kinase inhibitor H-7 dihydrochloride
CAS:Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Fórmula:C14H19Cl2N3O2SPureza:99.54%Cor e Forma:White Crystalline SolidPeso molecular:364.29Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Fórmula:C26H18ClN3O2Pureza:98.40%Cor e Forma:SolidPeso molecular:439.89Bisindolylmaleimide IV
CAS:Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)Fórmula:C20H13N3O2Pureza:98.83%Cor e Forma:Dark Red SolidPeso molecular:327.34Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Fórmula:C27H41N9O7Pureza:100% - 99.83%Cor e Forma:SolidPeso molecular:603.67Arg-Gly-Asp-Ser
CAS:Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Fórmula:C15H27N7O8Pureza:98.29%Cor e Forma:SolidPeso molecular:433.421,2-Dimyristoyl-sn-glycerol
CAS:1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..Fórmula:C31H60O5Pureza:99.49%Cor e Forma:White Powder With LumpsPeso molecular:512.81PD180970
CAS:PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Fórmula:C21H15Cl2FN4OPureza:98.47%Cor e Forma:SolidPeso molecular:429.27
