Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Produtos da "Sinalização Citoesquelética"
Ordenar por
NU074381b
NU074381b (compound 5b) is an effective inhibitor of S100A4, disrupting the formation of the S100A4-NMII complex with an IC50 value of 0.48 µM. Additionally, it inhibits cell proliferation and migration.Fórmula:C23H25ClN2O2Cor e Forma:SolidPeso molecular:396.91NDNA3
NDNA3 (compound 14) selectively inhibits Hsp90α with an IC50 of 0.51 μM, demonstrating low membrane permeability and minimal toxicity to Ovcar-8 and MCF-10AFórmula:C28H32N2O3SPureza:98%Cor e Forma:SolidPeso molecular:476.63CMPF
CAS:CMPF is a microtubule protein inhibitor that can be used to study tumors.Fórmula:C12H16O5Pureza:99.5%Cor e Forma:SolidPeso molecular:240.25HSF1A
CAS:HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.Fórmula:C21H19N3O2S2Pureza:98.89%Cor e Forma:SolidPeso molecular:409.52Ref: TM-T4125
1mg55,00€2mg88,00€5mg139,00€10mg207,00€25mg462,00€50mg677,00€100mg938,00€1mL*10mM (DMSO)130,00€Olverembatinib dimesylate
CAS:Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).Fórmula:C29H27F3N6O·2CH4O3SPureza:100% - 99.81%Cor e Forma:SolidPeso molecular:724.77Ref: TM-T2429
1mg39,00€2mg51,00€5mg84,00€10mg119,00€25mg229,00€50mg319,00€100mg474,00€1mL*10mM (DMSO)120,00€VnP-16
VnP-16 enhances bone formation by stimulating the differentiation and activity of osteoblasts via direct β1 integrin engagement, which subsequently activatesFórmula:C82H112N20O17Pureza:98%Cor e Forma:SolidPeso molecular:1649.89BCR-ABL-IN-7
CAS:BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.Fórmula:C19H16FN3O3SPureza:98.28%Cor e Forma:SolidPeso molecular:385.41PKCε Inhibitor Peptide acetate
PKCε Inhibitor Peptide acetate is a selective PKCε inhibitor containing the site for its specific receptor for activated C kinase (RACK).Fórmula:C39H69N9O15Pureza:98.93%Cor e Forma:SolidPeso molecular:904.02Ref: TM-T35827L
1mg65,00€2mg94,00€5mg116,00€10mg187,00€25mg314,00€50mg452,00€100mg620,00€200mg835,00€OSIP-486823
CAS:OSIP-486823(CP248) is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.Fórmula:C29H28FNO4Pureza:98.59%Cor e Forma:SolidPeso molecular:473.54Valecobulin hydrochloride
CAS:Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.Fórmula:C26H29ClN6O5SPureza:98.63%Cor e Forma:SolidPeso molecular:573.06Ref: TM-T13278
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)207,00€Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Fórmula:C14H16N2O3SPureza:98.59% - 99.19%Cor e Forma:SolidPeso molecular:292.35Ref: TM-T4048
1mg48,00€5mg78,00€10mg97,00€25mg188,00€50mg311,00€100mg502,00€500mg1.074,00€1mL*10mM (DMSO)87,00€HB-3-20
HB-3-20 induces the degradation of integrin αVβ5 on the cell surface. Transglutaminase 2 (TG2) specifically interacts with HB-3-20, exhibiting a catalytic efficiency (kcat/KM) of 0.16 μM^-1min^-1.Fórmula:C69H102N20O20Cor e Forma:SolidPeso molecular:1531.67Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Fórmula:C26H29Cl2N5O3Pureza:98.98% - 99.9%Cor e Forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecular:530.45AC 7739
CAS:AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.Fórmula:C18H22ClNO4Pureza:100% - 99.38%Cor e Forma:SoildPeso molecular:351.83Decursinol angelate
CAS:Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.Fórmula:C19H20O5Pureza:99.93%Cor e Forma:SolidPeso molecular:328.36(S)-Monastrol
CAS:Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Fórmula:C14H16N2O3SPureza:98%Cor e Forma:SolidPeso molecular:292.35Nocodazole
CAS:Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Fórmula:C14H11N3O3SPureza:98% - 99.91%Cor e Forma:Physical Description White Powder (Ntp 1992)Peso molecular:301.32Ref: TM-T2802
5mg37,00€10mg55,00€25mg99,00€50mg168,00€100mg283,00€200mg420,00€500mg682,00€1mL*10mM (DMSO)40,00€R59949
CAS:R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Fórmula:C28H25F2N3OSPureza:97.04%Cor e Forma:SolidPeso molecular:489.58Ref: TM-T26019
1mg47,00€5mg92,00€10mg145,00€25mg298,00€50mg465,00€100mg702,00€200mg938,00€1mL*10mM (DMSO)96,00€BCR-ABL-IN-10
BCR-ABL-IN-10 (compound B4) is a covalent BCR-ABL inhibitor featuring an arylvinylsulfonate (AVS) moiety, demonstrating an IC50 of 43.1 nM against ABL kinase. It forms a covalent and stable adduct with ABL kinase, enabling the sustained inhibition of intrinsic BCR-ABL activity. This compound is utilized in the study of chronic myeloid leukemia (CML).Fórmula:C24H22N4O5SCor e Forma:SolidPeso molecular:478.52PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.Fórmula:C78H132N30O18Pureza:98.78%Cor e Forma:SolidPeso molecular:1778.10
